HAFNI-enabled largescale platform for neuroimaging informatics (HELPNI)

Brain Informatics - Tập 2 - Trang 225-238 - 2015
Milad Makkie1, Shijie Zhao2,1, Xi Jiang1, Jinglei Lv2,1, Yu Zhao1, Bao Ge3,1, Xiang Li1, Junwei Han2, Tianming Liu1
1Cortical Architecture Imaging and Discovery Lab, Department of Computer Science and Bioimaging Research Center, The University of Georgia, Athens, USA
2School of Automation, Northwestern Polytechnical University, Xi’an, China
3School of Physics & Information Technology, Shaanxi Normal University, Xi’an, China

Tóm tắt

Tremendous efforts have thus been devoted on the establishment of functional MRI informatics systems that recruit a comprehensive collection of statistical/computational approaches for fMRI data analysis. However, the state-of-the-art fMRI informatics systems are especially designed for specific fMRI sessions or studies of which the data size is not really big, and thus has difficulty in handling fMRI ‘big data.’ Given the size of fMRI data are growing explosively recently due to the advancement of neuroimaging technologies, an effective and efficient fMRI informatics system which can process and analyze fMRI big data is much needed. To address this challenge, in this work, we introduce our newly developed informatics platform, namely, ‘HAFNI-enabled largescale platform for neuroimaging informatics (HELPNI).’ HELPNI implements our recently developed computational framework of sparse representation of whole-brain fMRI signals which is called holistic atlases of functional networks and interactions (HAFNI) for fMRI data analysis. HELPNI provides integrated solutions to archive and process large-scale fMRI data automatically and structurally, to extract and visualize meaningful results information from raw fMRI data, and to share open-access processed and raw data with other collaborators through web. We tested the proposed HELPNI platform using publicly available 1000 Functional Connectomes dataset including over 1200 subjects. We identified consistent and meaningful functional brain networks across individuals and populations based on resting state fMRI (rsfMRI) big data. Using efficient sampling module, the experimental results demonstrate that our HELPNI system has superior performance than other systems for large-scale fMRI data in terms of processing and storing the data and associated results much faster.

Tài liệu tham khảo

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