Gichttophi in Heberden-Knoten bei Hyperurikämie

Der Hautarzt - Tập 45 - Trang 799-802 - 1994
Ursula Peterseim1, Bettina von Gizycki-Nienhaus1, Manfred Schattenkirchner2, Michael Meurer1
1Dermatologische Klinik und Poliklinik (Direktor: Prof. Dr. G. Plewig) der Ludwig-Maximilians-Universität München, , DE
2Medizinische Poliklinik (Direktor: Prof. Dr. D. Schlöndorff) der Ludwig-Maximilians-Universität, München, Rheumaeinheit, , DE

Tóm tắt

The tophus is a characteristic and pathognomonic sign of chronic gout. Before effective drugs were available for the treatment of hyperuricaemia about 50 – 60% of patients with gout developed clinically and radiologically apparent urate crystal deposits. Clinical cutaneous manifestations of chronic gout are now rarely observed. However, the presence of degenerative tissues, as in idiopathic osteoarthritis of the fingers, may predispose to the deposition of urate crystals. We report on a patient with secondary – probably diuretic-induced – hyperuricaemia and gout tophi in Heberden's nodes.