Genome-wide association study identifies HLA-A*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population

Human Molecular Genetics - Tập 20 Số 5 - Trang 1034-1041 - 2011
Takeshi Ozeki1, Taisei Mushiroda1, Amara Yowang1, Atsushi Takahashi2, Michiaki Kubo3, Yuji Shirakata4, Zenrō Ikezawa5, Masafumi Iijima6, Tetsuo Shiohara7, Koji Hashimoto4, Naoyuki Kamatani2, Yusuke Nakamura8,1
1Research Group for Pharmacogenomics,
2Research Group for Medical Informatics and
3Research Group for Genotyping, RIKEN Center for Genomic Medicine, Yokohama 230-0045, Japan,
4Department of Dermatology, Ehime University Graduate School of Medicine, Ehime 791-0295, Japan
5Department of Dermatology, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan,
6Department of Dermatology, Showa University School of Medicine, Tokyo 142-8555, Japan,
7Department of Dermatology, Kyorin University School of Medicine, Tokyo 181-8611, Japan and
8Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan

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