Generation of a novel factor IX with augmented clotting activities in vitro and in vivo

Journal of Thrombosis and Haemostasis - Tập 8 - Trang 1773-1783 - 2010
C.N. LIN1, C.Y. KAO1, C.H. MIAO2,3, N. HAMAGUCHI4, H.L. WU5,6, G.Y. SHI5,6, Y.L. LIU7, K.A. HIGH7,8,9, S.W. LIN1,10
1Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei, Taiwan
2Seattle Children’s Hospital Research Institute
3Department of Pediatrics, University of Washington, Seattle, WA
4Department of Biochemistry, Brandeis University, Waltham, MA, USA
5Department of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University
6Cardiovascular Research Center, National Cheng Kung University, Tainan, Taiwan
7Division of Hematology and Center for Cellular and Molecular Therapeutics, The Children’s Hospital of Philadelphia
8Howard Hughes Medical Institute
9Department of Pediatrics, School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
10Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan

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