Gender differences in the long‐term outcome of alcohol dependence treatments: An analysis of twenty‐year prospective follow up

Drug and Alcohol Review - Tập 32 Số 4 - Trang 381-388 - 2013
Fabián Bravo1, Antoni Gual2, Anna Lligoña2, Joan Colom3
1Pontificia Universidad Javeriana Cali Department of Social Science Cali Colombia
2Alcohol Unit Psychiatry Department Clinical Institute of Neurosciences Hospital Clínic IDIBAPS Barcelona Spain
3Program on Substance Abuse General Directorate of Public Health Department of Health Generalitat de Catalunya Barcelona Spain

Tóm tắt

AbstractIntroduction and AimsWomen are underrepresented in long‐term studies of alcohol dependence. While gender differences in drinking behaviour have been observed when starting treatment, very few studies have investigated gender differences in long‐term drinking outcomes. This paper evaluates gender differences in the long‐term outcome of patients treated for alcohol dependence.Design and MethodsA cohort of 850 outpatients (19% women, age 39 ± 9 years) treated for alcohol dependence in specialist centres of Catalonia (Spain) were followed up prospectively for 20 years. Covariance analysis was used to assess gender differences at 1, 5, 10 and 20 years in drinking behaviour, psychosocial stress and social functioning (Axes 4 and 5 of Diagnostic and Statistical Manual of Mental Disorders, Third Edition, Revised). We evaluated gender differences in drinking trajectories using a multilevel model controlling for basal differences.ResultsWomen started treatment earlier in their drinking career, with more symptoms of dependence. In the first year they remained in treatment longer and had more clinic visits. Women presented lower alcohol consumption than men at baseline, 5 and 10 years, and similar levels of stress and psychosocial functioning. When basal alcohol consumption, length of treatment and employment were controlled, female gender predicted less drinking at year 1 and a drinking trajectory closer to abstinence between 1 and 20 years.Discussion and ConclusionsIncreased severity of alcohol dependence in women starting treatment was not associated with a worse prognosis. Women did better while under treatment and achieved a better long‐term drinking outcome. Gender differences were not relevant concerning psychosocial stress and social functioning. [Fabián Bravo, Antoni Gual, Anna Lligoña, Joan Colom. Gender differences in the long‐term outcome of alcohol dependence treatments: An analysis of twenty‐year prospective follow up. Drug Alcohol Rev 2013;32:381–388]

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Tài liệu tham khảo

10.3121/cmr.4.3.163

10.1016/j.drugalcdep.2007.08.013

Vaillant G, 1983, The natural history of alcoholism

10.15288/jsa.1995.56.218

10.15288/jsa.1999.60.252

10.1016/j.drugalcdep.2004.02.001

10.1056/NEJM199001113220205

10.1097/00005053-199304000-00001

10.1016/0306-4603(94)00037-Y

10.15288/jsa.2004.65.638

10.1081/JA-200042281

10.1007/s00406-007-0737-z

10.1016/j.drugalcdep.2007.08.017

10.1016/S0010-440X(95)90251-1

10.1016/S0741-8329(00)00102-6

10.1016/0740-5472(93)90099-N

10.1111/j.1360-0443.1991.tb01842.x

10.15288/jsa.1997.58.7

American Psychiatric Association, 1987, Diagnostic and statistical manual of mental disorders

Monras M, 2010, Differential features of female alcoholism, Adicciones, 22, 339

10.1093/alcalc/34.2.183

10.1157/13066382

10.1093/alcalc/agp032

10.1007/978-94-009-5644-5_5

10.1093/alcalc/34.2.153

10.1097/00005053-197308000-00002

Singer JD, 2003, Applied longitudinal data analysis: modeling change events occurrence, 10.1093/acprof:oso/9780195152968.001.0001

10.1046/j.1360-0443.2002.00142.x

10.1016/j.drugalcdep.2004.02.004

10.1176/appi.ajp.2009.09081161

Markez I, 2004, Women and psychotropics: the researching in the field of primary care, Rev Asoc Esp Neuropsiq, 91, 3302

10.1016/0899-3289(92)90020-X

10.1093/oxfordjournals.alcalc.a008298

10.1016/j.jsat.2004.12.010