Ganciclovir and the treatment of Epstein‐Barr virus hepatitis

Journal of Gastroenterology and Hepatology (Australia) - Tập 21 Số 11 - Trang 1758-1760 - 2006
Leon A. Adams1, Bastiaan DeBoer2, Gary P. Jeffrey3, Richard Marley1, George Garas1
1Department of Gastroenterology and Hepatology, Sir Charles Gardiner Hospital,
2Department of Pathology, Pathwest, Queen Elizabeth II Medical Center, and
3Department of Medicine, University of Western Australia, Perth, Western Australia Australia

Tóm tắt

Abstract

Epstein‐Barr virus (EBV) is part of the herpesvirus family that infects up to 90% of the population. Initial infection is often subclincal in children but will generally result in symptomatic infectious mononucleosis in adolescents and adults. Ganciclovir has been utilized in immunocompromised patients with EBV encephalitis and post‐liver transplant for EBV fulminant hepatitis. Herein, the successful use of ganciclovir in two immunocompetent patients with severe EBV hepatitis is reported.

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