Ganciclovir and the treatment of Epstein‐Barr virus hepatitis
Tóm tắt
Epstein‐Barr virus (EBV) is part of the herpesvirus family that infects up to 90% of the population. Initial infection is often subclincal in children but will generally result in symptomatic infectious mononucleosis in adolescents and adults. Ganciclovir has been utilized in immunocompromised patients with EBV encephalitis and post‐liver transplant for EBV fulminant hepatitis. Herein, the successful use of ganciclovir in two immunocompetent patients with severe EBV hepatitis is reported.
Từ khóa
Tài liệu tham khảo
Horwitz CA, 1980, Hepatic function in mononucleosis induced by Epstein‐Barr virus and cytomegalovirus, Clin. Chem., 26, 243, 10.1093/clinchem/26.2.243
Chang WY, 1975, Fatal infectious mononucleosis. Association with liver necrosis and herpes‐like virus particles, Arch. Pathol., 99, 185
Pelletier LL, 1976, Disseminated intravascular coagulation and hepatic necrosis: complications of infectious mononucleosis, JAMA, 235, 1144, 10.1001/jama.1976.03260370052037