Daniel Blankenberg1,2, Gregory Von Kuster1,2, Nathaniel Coraor1,2, Guruprasad Ananda1,2, Ross Lazarus3,1, Mary Mangan4, Anton Nekrutenko1,2, James Taylor5,1
1The Galaxy Team, Pennsylvania State University, University Park, Pennsylvania
2The Huck Institutes for the Life Sciences, Pennsylvania State University, University Park, Pennsylvania
3Channing Laboratory, Harvard Medical School, Boston, Massachusetts
4OpenHelix LLC, Bellevue, Washington
5Emory University, Atlanta, Georgia
Tóm tắt
AbstractHigh‐throughput data production has revolutionized molecular biology. However, massive increases in data generation capacity require analysis approaches that are more sophisticated, and often very computationally intensive. Thus, making sense of high‐throughput data requires informatics support. Galaxy (http://galaxyproject.org) is a software system that provides this support through a framework that gives experimentalists simple interfaces to powerful tools, while automatically managing the computational details. Galaxy is distributed both as a publicly available Web service, which provides tools for the analysis of genomic, comparative genomic, and functional genomic data, or a downloadable package that can be deployed in individual laboratories. Either way, it allows experimentalists without informatics or programming expertise to perform complex large‐scale analysis with just a Web browser. Curr. Protoc. Mol. Biol. 89:19.10.1‐19.10.21. © 2010 by John Wiley & Sons, Inc.
