Future risk of diabetes in mother and child after gestational diabetes mellitus

International Journal of Gynecology & Obstetrics - Tập 104 - Trang S25-S26 - 2009
Peter Damm1
1Center for Pregnant Women with Diabetes, Department of Obstetrics and Endocrinology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

Tóm tắt

AbstractGestational diabetes mellitus (GDM) is a common pregnancy complication with increased maternal and perinatal morbidity. However, significant long‐term morbidity also exists for the mother and offspring. Women with previous GDM have a very high risk of developing overt diabetes, primarily type 2 diabetes, later in life. Moreover, the risk of the metabolic syndrome is increased 3‐fold in these women. Their offspring have an 8‐fold risk of diabetes/prediabetes at 19–27 years of age. Thus, GDM is part of a vicious circle which increases the development of diabetes in the coming generations.

Tài liệu tham khảo

King H., 1998, Epidemiology of glucose intolerance and gestational diabetes in women of childbearing age, Diabetes Care, 21, B9 10.1056/NEJMoa042973 10.1007/978-1-4471-1680-6_26 10.3109/9781439802007.050 10.2337/diacare.25.10.1862 10.1016/S0002-9378(11)91559-2 10.2337/diacare.27.5.1194 10.1038/oby.2004.183 Verrma A., 2002, Insulin resistance syndrome in women with prior history of gestational diabetes mellitus, J Clin Endocrinol Metab, 87, 3227, 10.1210/jcem.87.7.8684 10.1210/jc.2004-1713 10.2337/diacare.26.7.2005 10.1056/NEJM200105033441801 Knowler W.C., 2002, Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin, N Engl J Med, 346, 393, 10.1056/NEJMoa012512 10.2337/diabetes.51.9.2796 10.1016/j.diabres.2003.08.009 10.1016/j.biocel.2005.07.006 10.2337/diab.40.2.S126 10.2337/dc07-s211 10.2337/dc07-1596 Seshiah V., 2008, Prevalence of gestational diabetes mellitus in South India (Tamil Nadu)–a community based study, J Assoc Phys India, 56, 329
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Thông tin xuất bản

International Journal of Gynecology & Obstetrics

Tập 104

S25-S26

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