Friction and Lubrication of Eye/Lens/Lid Interface: The Effect of Lubricant and Contact Lens Material

Tribology Letters - Tập 71 - Trang 1-18 - 2023
David Nečas1, Vlastimil Kulíšek1, Petr Štěpán2, František Ondreáš2,3, Pavel Čípek1, Gloria Huerta-Angeles2, Martin Vrbka1
1Faculty of Mechanical Engineering, Brno University of Technology, Brno, Czech Republic
2Contipro a.s, Dolní Dobrouč, Czech Republic
3Central European Institute of Technology, Brno University of Technology, Brno, Czech Republic

Tóm tắt

Irritation of the eye in the case of contact lens users may imply dry eye syndrome (DES), commonly treated by eye drops. The paper focuses on measuring the friction coefficient with the simultaneous observation of lubricating film formation of the simulated eye/lens/lid interface. The experiments are performed in a pin-on-plate setup under the linear reciprocal motion. The contact is lubricated by twelve different solutions as the potential ingredients for eye drops, focusing on the role of mucin, buffer type, and molecular weight (MW) of hyaluronic acid (HA). Two commercially available contact lenses are studied, while overall lens performance is evaluated, among others. The results showed that the lens material, the presence of mucin, and the type of buffer have a decisive influence on the contact behavior. Specifically, it is concluded that the selection of eye drops should reflect the type of lens the wearers use and the conditions of their tear film. The appropriate ingredient for Acuvue Oasys and Biofinity contact lenses is suggested based on the score of the biotribological performance of the lubricant, taking both friction and lubrication into account.

Tài liệu tham khảo

Lim, C.H.L., Stapleton, F., Mehta, J.S.: Review of contact lens-related complications. Eye Contact Lens: Sci. Clin. Pract. 44, S1–S10 (2018) Craig, J.P., Nichols, K.K., Akpek, E.K., Caffery, B., Dua, H.S., Joo, C.-K., Liu, Z., Nelson, J.D., Nichols, J.J., Tsubota, K., et al.: TFOS DEWS II definition and classification report. Ocul. Surf. 15, 276–283 (2017) Černohlávek, M., Brandejsová, M., Štěpán, P., Vagnerová, H., Hermannová, M., Kopecká, K., Kulhánek, J., Nečas, D., Vrbka, M., Velebný, V., et al.: Insight into the lubrication and adhesion properties of hyaluronan for ocular drug delivery. Biomolecules 11(10), 1431 (2021) Rebenda, D., Vrbka, M., Čípek, P., Toropitsyn, E., Nečas, D., Pravda, M., Hartl, M.: On the dependence of rheology of hyaluronic acid solutions and frictional behavior of articular cartilage. Materials 13(11), 2659 (2020) Furmann, D., Nečas, D., Rebenda, D., Čípek, P., Vrbka, M., Křupka, I., Hartl, M.: The effect of synovial fluid composition, speed and load on frictional behaviour of articular cartilage. Materials 13(6), 1334 (2020) Streďanská, A., Nečas, D., Vrbka, M., Křupka, I., Hartl, M., Toropitsyn, E., Husby, J.: Development of tribological model of human fascia: the influence of material hardness and motion speed. Biotribology 30, 100209 (2022) Lo, J., Lange, D., Chew, B.: Ureteral stents and foley catheters-associated urinary tract infections: the role of coatings and materials in infection prevention. Antibiotics 3, 87–97 (2014) Lin, C., Wan, H., Kaper, H.J., Sharma, P.K.: A hyaluronic acid based lubricious coating for cardiovascular catheters. Tribol. Int. 151, 106495 (2020) Nečas, D., Vrbka, M., Gallo, J., Křupka, I., Hartl, M.: On the observation of lubrication mechanisms within hip joint replacements. Part II: hard-on-hard bearing pairs. J. Mech. Behav. Biomed. Mater. 89, 249–259 (2019) Nečas, D., Vrbka, M., Marian, M., Rothammer, B., Tremmel, S., Wartzack, S., Galandáková, A., Gallo, J., Wimmer, M.A., Křupka, I., et al.: Towards the understanding of lubrication mechanisms in total knee replacements – part I: experimental investigations. Tribol. Int. 156, 106874 (2021) Nairn, J.A., Jiang, T.B.: Measurement of the friction and lubricity properties of contact lenses. Proceedings of ANTEC 95, Boston, MA, May 7–11 (1995) Ngai, V., Medley, J.B., Jones, L., Forrest, J., Teiehroeb, J.: Friction of contact lenses: silicone hydrogel versus conventional hydrogel. In: Life Cycle Tribology Tribology and Interface Engineering Series, pp. 371–379. Elsevier (2005) . (ISBN 9780444516879) Rennie, A.C., Dickrell, P.L., Sawyer, W.G.: Friction coefficient of soft contact lenses: measurements and modeling. Tribol. Lett. 18, 499–504 (2005) Dunn, A.C., Tichy, J.A., Urueña, J.M., Sawyer, W.G.: Lubrication regimes in contact lens wear during a blink. Tribol. Int. 63, 45–50 (2013) Roba, M., Duncan, E.G., Hill, G.A., Spencer, N.D., Tosatti, S.G.P.: Friction measurements on contact lenses in their operating environment. Tribol. Lett. 44, 387–397 (2011) Sterner, O., Aeschlimann, R., Zürcher, S., Scales, C., Riederer, D., Spencer, N.D., Tosatti, S.G.P.: Tribological classification of contact lenses: from coefficient of friction to sliding work. Tribol. Lett. 63, 1–3 (2016) An, J., Dėdinaitė, A., Nilsson, A., Holgersson, J., Claesson, P.M.: Comparison of a brush-with-anchor and a train-of-brushes mucin on poly(methyl methacrylate) surfaces: adsorption, surface forces, and friction. Biomacromol 15, 1515–1525 (2014) Sterner, O., Karageorgaki, C., Zürcher, M., Zürcher, S., Scales, C.W., Fadli, Z., Spencer, N.D., Tosatti, S.G.P.: Reducing friction in the eye: a comparative study of lubrication by surface-anchored synthetic and natural ocular mucin analogues. ACS Appl. Mater. Interfaces 9, 20150–20160 (2017) Urueña, J.M., Dunn, A.C., Sawyer, W.G.: Contact lens boundary lubrication and friction reduction with hyaluronic acid. Tribol. Lubr. Technol. 67, 14–15 (2011) Kaya, S., Schmidl, D., Schmetterer, L., Witkowska, K.J., Unterhuber, A., dos Santos, V.A., Baar, C., Garhöfer, G., Werkmeister, R.M.: Effect of hyaluronic acid on tear film thickness as assessed with ultra-high resolution optical coherence tomography. Acta Ophthalmol. 93, 439–443 (2015) Mabuchi, K., Iwashita, H., Sakai, R., Ujihira, M., Hori, Y.: Development of a pendulum machine for measuring contact lens friction. Biosurf. Biotribol. 7, 154–161 (2021) Iwashita, H., Mabuchi, K., Itokawa, T., Okajima, Y., Suzuki, T., Hori, Y.: Evaluation of the lubricating effect of hyaluronic acid on contact lenses using a pendulum-type friction tester under mimicking physiological conditions. Eye Contact Lens Sci. Clin. Pract. 48, 83–87 (2022) Contipro a.s. Speciality hyaluronan chemicals. https://www.contipro.com/images/documents/Speciality-hyaluronan-chemicals.pdf Salzillo, R., Schiraldi, C., Corsuto, L., D’Agostino, A., Filosa, R., De Rosa, M., et al.: Optimization of hyaluronan-based eye drop formulations. Carbohyd. Polym. 153, 275–283 (2016) Čípek, P., Vrbka, M., Rebenda, D., Nečas, D., Křupka, I.: Biotribology of synovial cartilage: role of albumin in adsorbed film formation. Eng. Sci. Technol. Int. J. 34, 101090 (2022) Čípek, P., Vrbka, M., Rebenda, D., Nečas, D., Křupka, I.: Biotribology of synovial cartilage: a new method for visualization of lubricating film and simultaneous measurement of the friction coefficient. Materials 13(9), 2075 (2020) Čípek, P., Rebenda, D., Nečas, D., Vrbka, M., Křupka, I., Hartl, M.: Visualization of lubrication film in model of synovial joint. Tribol. Ind. 41, 387–393 (2019) Azushima, A.: In situ 3D measurement of lubrication behavior at interface between tool and workpiece by direct fluorescence observation technique. Wear 260, 243–248 (2006) Nečas, D., Vrbka, M., Galandáková, A., Křupka, I., Hartl, M.: On the observation of lubrication mechanisms within hip joint replacements. Part I: hard-on-soft bearing pairs. J. Mech. Behav. Biomed. Mater. 89, 237–248 (2019) Sindt, C.W., Longmuir, R.A.: Contact lens strategies for the patient with dry eye. Ocul. Surf. 5, 294–307 (2007) Read, M.L., Morgan, P.B., Kelly, J.M., Maldonado-Codina, C.: Dynamic contact angle analysis of silicone hydrogel contact lenses. J. Biomater. Appl. 26, 85–99 (2011) Chaudhri, M.M., Yoffe, E.H.: The area of contact between a small sphere and a flat surface. Philos. Mag. A 44, 667–675 (2006) Rebenda, D., Vrbka, M., Nečas, D., Toropitsyn, E., Yarimitsu, S., Čípek, P., et al.: Rheological and frictional analysis of viscosupplements towards improved lubrication of human joints. Tribol. Int. 160, 107030 (2021) Nečas, D., Yarimitsu, S., Rebenda, D., Shinmori, H., Vrbka, M., Sawae, Y., et al.: On the replacement of articular cartilage: the friction of PVA hydrogel layer in hip simulator test. Tribol. Int. 178, 108100 (2023) Švecová, E., Ostatná, V., Fojt, L., Hermannová, M., Velebný, V., Ondreáš, F.: Adsorption/desorption behavior of hyaluronic acid fragments at charged hydrophobic surface. Carbohydr. Polym. 277, 118831 (2022) Cleland, R.L., Wang, J.L., Detweiler, D.M.: Polyelectrolyte properties of sodium hyaluronate. 2. Potentiometric titration of hyaluronic acid. Macromolecules 15, 386–395 (1982) Ondreas, F., Dusankova, M., Sita, J., Cepa, M., Stepan, J., Belsky, P., et al.: Self-assembly of hydrophobically modified hyaluronic acid. Appl. Surf. Sci. 546, 149161 (2021) Buhler, E., Boué, F.: Chain persistence length and structure in hyaluronan solutions: ionic strength dependence for a model semirigid polyelectrolyte. Macromolecules 37, 1600–1610 (2004) Chang, D.P., Abu-Lail, N.I., Coles, J.M., Guilak, F., Jay, G.D., Zauscher, S.: Friction force microscopy of lubricin and hyaluronic acid between hydrophobic and hydrophilic surfaces. Soft Matter 5(18), 3438 (2009) Yamasaki, K., Drolle, E., Nakagawa, H., Hisamura, R., Ngo, W., Jones, L.: Impact of a low molecular weight hyaluronic acid derivative on contact lens wettability. Contact Lens Anterior Eye 44(3), 101334 (2021) Lee, S.: Characterization of lubricity of mucins at polymeric surfaces for biomedical applications. J. Biomed. Biol. Eng. 75(3), 145–150 (2013) Yakubov, G.E., McColl, J., Bongaerts, J.H.H., Ramsden, J.J.: Viscous boundary lubrication of hydrophobic surfaces by mucin. Langmuir 25, 2313–2321 (2009) Wang, X., Du, M., Han, H., Song, Y., Zheng, Q.: Boundary lubrication by associative mucin. Langmuir 31, 4733–4740 (2015) Feiler, A.A., Sahlholm, A., Sandberg, T., Caldwell, K.D.: Adsorption and viscoelastic properties of fractionated mucin (BSM) and bovine serum albumin (BSA) studied with quartz crystal microbalance (QCM-D). J. Colloid Interface Sci. 315, 475–481 (2007) Yakubov, G.E., Papagiannopoulos, A., Rat, E., Easton, R.L., Waigh, T.A.: Molecular structure and rheological properties of short-side-chain heavily glycosylated porcine stomach mucin. Biomacromol 8, 3467–3477 (2007) Khutoryanskiy, V.V.: Advances in mucoadhesion and mucoadhesive polymers. Macromol. Biosci. 11, 748–764 (2011) Bayer, I.S.: Recent advances in mucoadhesive interface materials, mucoadhesion characterization, and technologies. Adv. Mater. Interfaces 9(18), 2200211 (2022) Lewandowska, K., Szulc, M.: Characterisation of hyaluronic acid blends modified by poly(N-Vinylpyrrolidone). Molecules 26(17), 5233 (2021) Jahn, S., Klein, J.: Hydration Lubrication: the macromolecular domain. Macromolecules 48, 5059–5075 (2015) Lee, S., Müller, M., Rezwan, K., Spencer, N.D.: Porcine gastric mucin (PGM) at the water/poly(dimethylsiloxane) (PDMS) interface: influence of pH and ionic strength on its conformation, adsorption, and aqueous lubrication properties. Langmuir 21, 8344–8353 (2005) Hall, B., Jones, L., Forrest, J.A.: Measuring the kinetics and activity of adsorbed proteins: in vitro lysozyme deposited onto hydrogel contact lenses over short time periods. J. Biomed. Mater. Res., Part A 101A, 755–764 (2013) Giraldez, M.J., Resua, C.G., Lira, M., Real Oliveira, M.E.C.D., Magariños, B., Toranzo, A.E., et al.: Contact lens hydrophobicity and roughness effects on bacterial adhesion. Optom. Vis. Sci. 87, E426–E431 (2010) Sterner, O., Aeschlimann, R., Zürcher, S., Osborn Lorenz, K., Kakkassery, J., Spencer, N.D., et al.: Friction measurements on contact lenses in a physiologically relevant environment: effect of testing conditions on friction. Investig. Opthalmol. Vis. Sci. 57(13), 5383–5392 (2016) Lee, S., Müller, M., Ratoi-Salagean, M., Vörös, J., Pasche, S., De Paul, S.M., et al.: Tribol. Lett. 15, 231–239 (2003) Müller, M., Lee, S., Spikes, H.A., Spencer, N.D.: The influence of molecular architecture on the macroscopic lubrication properties of the brush-like co-polyelectrolyte poly(L-lysine)- g -poly(ethylene glycol) (PLL- g -PEG) adsorbed on oxide surfaces. Tribol. Lett. 15, 395–405 (2003) Klein, J., Kumacheva, E., Mahalu, D., Perahia, D., Fetters, L.J.: Reduction of frictional forces between solid surfaces bearing polymer brushes. Nature 370, 634–636 (1994) Baszkin, A.: Surface phenomena in biocomponent—polymer systems: a case study of mucin adsorption on polymers with different hydrophilicities. In: Biologically Modified Polymeric Biomaterial Surfaces, pp. 119–123. Springer, Netherlands, Dordrecht (1993) Senaratne, W., Andruzzi, L., Ober, C.K.: Self-assembled monolayers and polymer brushes in biotechnology: current applications and future perspectives. Biomacromol 6, 2427–2448 (2005) Seo, J., Byun, W.Y., Alisafaei, F., Georgescu, A., Yi, Y.-S., Massaro-Giordano, M., et al.: Multiscale reverse engineering of the human ocular surface. Nat. Med. 25, 1310–1318 (2019) Kwon, K.-A., Shipley, R.J., Edirisinghe, M., Ezra, D.G., Rose, G., Best, S.M., et al.: High-speed camera characterization of voluntary eye blinking kinematics. J. R. Soc. Interface 10(85), 20130227 (2013)