Fragrance contact dermatitis – a worldwide multicenter investigation (Part III)

Contact Dermatitis - Tập 46 Số 3 - Trang 141-144 - 2002
Walter G. Larsen1, Hideo Nakayama2, Torkil Fischer3, Peter Elsner4, Peter J. Frosch5, Desmond Burrows6, William P. Jordan7, S. Shaw8, John Wilkinson8, James G. Marks9, Makoto Sugawara10, Marc Nethercott11, James R. Nethercott11
1Portland, Oregon, USA
2Tokyo, Japan
3Solna, Sweden
4Zurich, Switzerland
5Dortmund, Germany
6Belfast, Northern Ireland
7Richmond, Virginia
8Amersham, England
9Hershey, Pennsylvania
10Yokohama, Japan
11Baltimore, Maryland (deceased)

Tóm tắt

The purpose of this study was to determine the frequency of responses to selected fragrance materials in patients who were fragrance sensitive. 218 fragrance sensitive subjects were evaluated in eight centres worldwide with a fragrance mixture (FM) and 17 less well‐studied fragrance materials. Reaction to the fragrance mixture (FM) occurred in 76% of the subjects. The (FM) detected all reactions to nerol and hydroxycitronellol and 93% of the reactions to clove bud oil. Ten fragrance materials were not detected by the FM and deserve further study: benzenepropanol, beta, beta, 3‐trimethyl, hexyl‐salicylate, dl‐citronellol, synthetic ylang ylang oil, benzyl mixture, cyclohexyl‐acetate, eugenyl methyl ether, isoeugenyl methyl ether, 3‐phenyl‐1‐propanol, and 3, 7‐dimethyl‐7‐methoxyoctan‐2‐ol.

Từ khóa


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Contact Dermatitis

Tập 46 Số 3

141-144

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