Fluorescence imaging in optical diffusion tomography

Proceedings IEEE International Symposium on Biomedical Imaging - Trang 58-61
A.B. Milstein1, Q. Zhang2,3, S. Oh1, K.J. Webb4, C.A. Bouman4, R.R. Millane5, D.A. Boas3
1School of Electrical and Computer Engineering, Purdue University, West Lafayette, IN, USA
2NMR Center, Harvard Medical School and Massachusetts General Hospital, Charlestown, MA, USA
3Massachusetts General Hospital, Harvard Medical School, Charlestown, MA
4School of Electrical and Computer Engineering, Purdue University, West Lafayette, IN
5Dept. of Electrical and Computer Engineering, University of Canterbury, Christchurch, New Zealand

Tóm tắt

A Bayesian optimization scheme is presented for reconstructing fluorescent yield and lifetime, the absorption coefficient, and the scattering coefficient in turbid media, such as biological tissue. The proposed method utilizes measurements at both the excitation and emission wavelengths for reconstructing all unknown parameters. A tissue phantom experiment uses the inversion strategy to reconstruct a spherical heterogeneity containing indocyanine green.

Từ khóa

#Fluorescence #Optical imaging #Tomography #Image reconstruction #Optical scattering #Biomedical optical imaging #Stimulated emission #Bayesian methods #Absorption #Biological tissues

Tài liệu tham khảo

10.1117/12.434493 10.1364/AO.38.004930 10.1364/AO.30.004507 10.1364/AO.12.000555 10.1364/OL.27.000095 10.1111/j.1751-1097.1997.tb03138.x 10.1364/OL.21.000158 10.1364/AO.40.002206 10.1364/OL.26.000893 10.1364/JOSAA.14.000288 10.1111/j.1751-1097.1997.tb08648.x 10.1111/j.1751-1097.1999.tb01953.x 10.1364/JOSAA.16.002400
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Proceedings IEEE International Symposium on Biomedical Imaging

58-61

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