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Chi phí liên quan đến hội chứng fibromyalgia và sự mất mát năng suất: một gánh nặng xã hội đáng kể
Tóm tắt
Nghiên cứu này nhằm mô tả việc sử dụng tài nguyên chăm sóc sức khỏe liên quan đến cơn đau, chi phí trực tiếp và sự mất mát năng suất ở những bệnh nhân mắc hội chứng fibromyalgia (FMS). Một nghiên cứu chi phí bệnh tật đã được thực hiện với mẫu 57 người lớn được chẩn đoán mắc FMS tại tỉnh Quebec (Canada). Dữ liệu về chi phí trực tiếp liên quan đến FMS và sự mất mát năng suất từ công việc trả lương và không trả lương trong vòng ba tháng đã được thu thập bằng cách sử dụng một giao thức phỏng vấn điện thoại có cấu trúc tiêu chuẩn hóa. Chi phí trực tiếp được định giá bằng đô la Canada năm 2009 theo góc nhìn của xã hội. Kết quả cho thấy chi phí trực tiếp trung bình trong ba tháng lên tới 951 đô la mỗi bệnh nhân (SD: 710), tương đương với chi phí hàng năm trung bình là 3804 đô la. Việc mua thuốc theo chỉ định của bác sĩ dẫn đến chi phí cao nhất (trung bình: 329 đô la, SD: 321), tiếp theo là tư vấn của các chuyên gia chăm sóc sức khỏe ngoài bác sĩ (trung bình: 129 đô la, SD: 222) và tư vấn của bác sĩ (trung bình: 98 đô la, SD: 116). Kết quả cũng cho thấy gánh nặng kinh tế cao cho chính bệnh nhân, bên cạnh các chi phí được bảo hiểm công hoặc tư chi trả. Trong số những người tham gia có công việc trả lương (45.6%), trung bình có 5.6 ngày (SD: 13.2) bị mất do cơn đau trong 3 tháng qua. Trong số những người không có việc làm (54.4%), trung bình có 25.1 ngày trong năng suất gia đình (SD: 24.8) bị mất. FMS liên quan đến một gánh nặng kinh tế xã hội đáng kể. Cần có thêm nghiên cứu rõ ràng để cải thiện việc quản lý loại rối loạn này và đưa ra quyết định tốt hơn về phân bổ nguồn lực.
Từ khóa
#hội chứng fibromyalgia #chi phí y tế #năng suất lao động #gánh nặng kinh tế xã hộiTài liệu tham khảo
Wolfe F, Clauw DJ, Fitzcharles MA, Goldenberg DL, Katz RS, Mease P, Russell AS, Russell IJ, Winfield JB, Yunus MB. The American College of Rheumatology preliminary diagnostic criteria for fibromyalgia and measurement of symptom severity. Arthritis Care Res. 2010;62(5):600–10.
Gran JT. The epidemiology of chronic generalized musculoskeletal pain. Best Pract Res Clin Rheumatol. 2003;17(4):547–61.
Branco JC, Bannwarth B, Failde I, Abello Carbonell J, Blotman F, Spaeth M, Saraiva F, Nacci F, Thomas E, Caubere JP. Prevalence of fibromyalgia: a survey in five European countries. Semin Arthritis Rheum. 2010;39(6):448–53.
McGillion MH, Watt-Watson J, Stevens B, Lefort SM, Coyte P, Graham A. Randomized controlled trial of a psychoeducation program for the self-management of chronic cardiac pain. J Pain Symptom Manage. 2008;36(2):126–40.
White KP, Speechley M, Harth M, Ostbye T. The London Fibromyalgia Epidemiology Study: the prevalence of fibromyalgia syndrome in London, Ontario. J Rheumatol. 1999;26(7):1570–6.
Da Costa D, Dobkin PL, Fitzcharles M, Fortin PR, Beaulieu A, Zummer M, Senecal J, Goulet JR, Rich E, Choquette D. Determinants of health status in fibromyalgia: a comparative study with systemic lupus erythematosus. J Rheumatol. 2000;27(2):365–72.
Bennett RM, Schein J, Kosinski MR, Hewitt DJ, Jordan DM, Rosenthal NR. Impact of fibromyalgia pain on health‐related quality of life before and after treatment with tramadol/acetaminophen. Arthritis Care Res. 2005;53(4):519–27.
Oliveira PJ, Costa ME. Relationships Among Affect, Emotional Distress, and Physical Health Status in Fibromyalgia. J Autoimmun Dis Rheumatol. 2013;1(1):11–8.
Bigatti SM, Cronan TA. An examination of the physical health, health care use, and psychological well-being of spouses of people with fibromyalgia syndrome. Health Psychol. 2002;21(2):157–66.
Hoffman D, Dukes E. The health status burden of people with fibromyalgia: a review of studies that assessed health status with the SF‐36 or the SF‐12. Int J Clin Pract. 2008;62(1):115–26.
Berger ML, Bingefors K, Heldblom EC, Pashos CL, Torrance GW, Dix SM. Health care cost, quality, and outcomes: ISPOR Book of terms. Lawrenceville: International Society for Pharmacoeconomics and Outcomes Research; 2010.
Larg A, Moss J. Cost-of-illness studies: a guide to critical evaluation. Pharmacoeconomics. 2011;29(8):653–71.
Tarricone R. Cost-of-illness analysis. What room in health economics? Health Policy. 2006;77(1):51–63.
Neumann PJ. Costing and perspective in published cost-effectiveness analysis. Med Care. 2009;47(7 Suppl 1):S28–32.
Berger A, Dukes E, Martin S, Edelsberg J, Oster G. Characteristics and healthcare costs of patients with fibromyalgia syndrome. Int J Clin Pract. 2007;61(9):1498–508.
Berger A, Sadosky A, Dukes EM, Edelsberg J, Zlateva G, Oster G. Patterns of healthcare utilization and cost in patients with newly diagnosed fibromyalgia. Am J Manag Care. 2010;16(5 Suppl):S126–37.
Boonen A, van den Heuvel R, van Tubergen A, Goossens M, Severens J, van der Heijde D, van der Linden S. Large differences in cost of illness and wellbeing between patients with fibromyalgia, chronic low back pain, or ankylosing spondylitis. Ann Rheum Dis. 2005;64(3):396–402.
Doron Y, Peleg R, Peleg A, Neumann L, Buskila D. The clinical and economic burden of fibromyalgia compared with diabetes mellitus and hypertension among Bedouin women in the Negev. Fam Pract. 2004;21(4):415–9.
Kleinman N, Harnett J, Melkonian A, Lynch W, Kaplan-Machlis B, Silverman SL. Burden of fibromyalgia and comparisons with osteoarthritis in the workforce. J Occup Environ Med. 2009;51(12):1384–93.
Lachaine J, Beauchemin C, Landry P-A. Clinical and economic characteristics of patients with fibromyalgia syndrome. Clin J Pain. 2010;26(4):284–90.
Lind BK, Lafferty WE, Tyree PT, Diehr PK, Grembowski DE. Use of complementary and alternative medicine providers by fibromyalgia patients under insurance coverage. Arthritis Care Res. 2007;57(1):71–6.
Sanchez R, Uribe C, Li H, Alvir J, Deminski M, Chandran A, Palacio A. Longitudinal evaluation of health care utilization and costs during the first three years after a new diagnosis of fibromyalgia. Curr Med Res Opin. 2011;27(3):663–71.
Palacio A, Uribe CL, Li H, Hanna J, Deminski M, Alvir J, Chandran A, Sanchez R. Financial and clinical characteristics of fibromyalgia: a case–control comparison. Am J Manag Care. 2010;16(5 Suppl):S118–25.
Penrod JR, Bernatsky S, Adam V, Baron M, Dayan N, Dobkin PL. Health services costs and their determinants in women with fibromyalgia. J Rheumatol. 2004;31(7):1391–8.
Rivera J, Rejas J, Esteve-Vives J, Vallejo MA. Resource utilisation and health care costs in patients diagnosed with fibromyalgia in Spain. Clin Exp Rheumatol. 2009;27(5 Suppl 56):S39–45.
Robinson RL, Birnbaum HG, Morley MA, Sisitsky T, Greenberg PE, Claxton AJ. Economic cost and epidemiological characteristics of patients with fibromyalgia claims. J Rheumatol. 2003;30(6):1318–25.
Robinson RL, Birnbaum HG, Morley MA, Sisitsky T, Greenberg PE, Wolfe F. Depression and fibromyalgia: treatment and cost when diagnosed separately or concurrently. J Rheumatol. 2004;31(8):1621–9.
Sicras-Mainar A, Rejas J, Navarro R, Blanca M, Morcillo Á, Larios R, Velasco S, Villaroya C. Treating patients with fibromyalgia in primary care settings under routine medical practice: a claim database cost and burden of illness study. Arthritis Res Ther. 2009;11(2):R54.
Thompson JM, Luedtke CA, Oh TH, Shah ND, Long KH, King S, Branda M, Swanson R. Direct medical costs in patients with fibromyalgia: cost of illness and impact of a brief multidisciplinary treatment program. Am J Phys Med Rehabil. 2011;90(1):40–6.
Wassem R, Hendrix TJ. Direct and indirect costs of fibromyalgia to patients and their families. J Orthop Nurs. 2003;7(1):26–32.
White LA, Birnbaum HG, Kaltenboeck A, Tang J, Mallett D, Robinson RL. Employees with fibromyalgia: medical comorbidity, healthcare costs, and work loss. J Occup Environ Med. 2008;50(1):13–24.
Wolfe F, Anderson J, Harkness D, Bennett RM, Caro XJ, Goldenberg DL, Russell IJ, Yunus MB. A prospective, longitudinal, multicenter study of service utilization and costs in fibromyalgia. Arthritis Rheum. 1997;40(9):1560–70.
Santoro MS, Cronan TA. Depression, self-efficacy, health status, and health care costs: A comparison of men with fibromyalgia or osteoarthritis. J Musculoskelet Pain. 2013;21(2):126–34.
Jeffery DD, Bulathsinhala L, Kroc M, Dorris J. Prevalence, Health Care Utilization, and Costs of Fibromyalgia, Irritable Bowel, and Chronic Fatigue Syndromes in the Military Health System, 2006–2010. Mil Med. 2014;179(9):1021–9.
White KP, Speechley M, Harth M, Ostbye T. The London fibromyalgia epidemiology study: Direct health care costs of fibromyalgia syndrome in London, Canada. J Rheumatol. 1999;26(4):885–9.
Silverman S, Dukes EM, Johnston SS, Brandenburg NA, Sadosky A, Huse DM. The economic burden of fibromyalgia: Comparative analysis with rheumatoid arthritis. Curr Med Res Opin. 2009;25(4):829–40.
Clabaugh G, Ward MM. Cost‐of‐Illness Studies in the United States: A Systematic Review of Methodologies Used for Direct Cost. Value Health. 2008;11(1):13–21.
Health Canada. Canada’s Health Care System. http://www.hc-sc.gc.ca/hcs-sss/pubs/system-regime/2011-hcs-sss/index-eng.php. Accessed 26 March 2015
Régie de l’assurance maladie du Québec. Rapport annuel de gestion 2011–2012. Québec: Gouvernement du Québec; 2012.
Bourgault P, Lacasse A, Marchand S, Courtemanche-Harel R, Charest J, Gaumond I, BarcellosdeSouza J, Choiniere M. Multicomponent interdisciplinary group intervention for self-management of fibromyalgia: a mixed-methods randomized controlled trial. PLoS ONE. 2015;10(5):e0126324.
Wolfe F, Smythe HA, Yunus MB, Bennett RM, Bombardier C, Goldenberg DL, Tugwell P, Campbell SM, Abeles M, Clark P. The American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia. Report of the Multicenter Criteria Committee. Arthritis Rheum. 1990;33(2):160–72.
Bhandari A, Wagner T. Self-reported utilization of health care services: improving measurement and accuracy. Med Care Res Rev. 2006;63(2):217–35.
Lensberg BR, Drummond MF, Danchenko N, Despiegel N, Francois C. Challenges in measuring and valuing productivity costs, and their relevance in mood disorders. Clinicoecon Outcomes Res. 2013;5:565–73.
Guerriere DN, Choiniere M, Dion D, Peng P, Stafford-Coyte E, Zagorski B, Banner R, Barton PM, Boulanger A, Clark AJ. The Canadian STOP-PAIN project - Part 2: What is the cost of pain for patients on waitlists of multidisciplinary pain treatment facilities? Can J Anaesth. 2010;57(6):549–58.
Fitzcharles M-A, Ste-Marie PA, Goldenberg DL, Pereira JX, Abbey S, Choiniere M, Ko G, Moulin DE, Panopalis P, Proulx J. 2012 Canadian Guidelines for the diagnosis and management of fibromyalgia syndrome: Executive summary. Pain Res Manag. 2012;18(3):119–26.
Fitzcharles MA, Ste-Marie PA, Goldenberg DL, Pereira JX, Abbey S, Choiniere M, Ko G, Moulin DE, Panopalis P, Proulx J. Canadian Pain Society and Canadian Rheumatology Association recommendations for rational care of persons with fibromyalgia. A summary report. J Rheumatol. 2013;40(8):1388–93.
Han C, Lee SJ, Lee SY, Seo HJ, Wang SM, Park MH, Patkar AA, Koh J, Masand PS, Pae CU. Available therapies and current management of fibromyalgia: focusing on pharmacological agents. Drugs Today (Barcelona, Spain: 1998). 2011;47(7):539–57.
Sim J, Adams N. Systematic review of randomized controlled trials of nonpharmacological interventions for fibromyalgia. Clin J Pain. 2002;18(5):324–36.
Rossy LA, Buckelew SP, Dorr N, Hagglund KJ, Thayer JF, McIntosh MJ, Hewett JE, Johnson JC. A meta-analysis of fibromyalgia treatment interventions. Ann Behav Med. 1999;21(2):180–91.
Argoff CE, Albrecht P, Irving G, Rice F. Multimodal analgesia for chronic pain: rationale and future directions. Pain Med. 2009;10 Suppl 2:S53–66.
American Society of Anesthesiologists Task Force on Chronic Pain Management & American Society of Regional Anesthesia and Pain Medicine. Practice guidelines for chronic pain management: An updated report by the American Society of Anesthesiologists Task Force on Chronic Pain Management and the American Society of Regional Anesthesia and Pain Medicine. Anesthesiology. 2010;112(4):810–33.
Sommer C. Fibromyalgia: A Clinical Update. Pain. 2010;XVIII(4):1-4.
Turk DC, Swanson KS, Tunks ER. Psychological approaches in the treatment of chronic pain patients--when pills, scalpels, and needles are not enough. Can J Psychiatry. 2008;53(4):213–23.
Vij B, Whipple MO, Tepper SJ, Mohabbat AB, Stillman M, Vincent A. Frequency of Migraine Headaches in Patients With Fibromyalgia. Headache. 2015;55(6):860–5.
Zuccaro SM, Vellucci R, Sarzi-Puttini P, Cherubino P, Labianca R, Fornasari D. Barriers to pain management: focus on opioid therapy. Clin Drug Investig. 2012;32 Suppl 1:11–9.
MacDonald NE, Flegel K, Hebert PC, Stanbrook MB. Better management of chronic pain care for all. CMAJ. 2011;183(16):1815.
AETMIS. Prise en charge de la douleur chronique (non cancéreuse): Organisation des services de santé. Montréal: Agence d’évaluation des technologies et des modes d’intervention en santé; 2006.
Kingma EM, Rosmalen JG. The power of longitudinal population-based studies for investigating the etiology of chronic widespread pain. Pain. 2012;153(12):2305–6.
Sessle BJ. The pain crisis: what it is and what can be done. Pain Res Treat. 2012;703947:1–6.
Arnold LM, Clauw DJ, McCarberg BH, FibroCollaborative. Improving the recognition and diagnosis of fibromyalgia. Mayo Clin Proc. 2011;86(5):457–64.