Fibrinogen αC‐regions are not directly involved in fibrin polymerization as evidenced by a “Double‐Detroit” recombinant fibrinogen mutant and knobs‐mimic peptides

Journal of Thrombosis and Haemostasis - Tập 18 - Trang 802-814 - 2020
Cédric Duval1, Aldo Profumo2, Anna Aprile2, Annalisa Salis3, Enrico Millo3, Gianluca Damonte3, Julia S. Gauer1, Robert A.S. Ariëns1, Mattia Rocco2
1Leeds Thrombosis Collective, Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK
2Biopolimeri e Proteomica, IRCCS Ospedale Policlinico San Martino, Genova, Italy
3Department of Experimental Medicine, Center of Excellence for Biomedical Research (CEBR), University of Genova, Genova, Italy

Tài liệu tham khảo

Koster, 1994, Factor VII and fibrinogen levels as risk factors for venous thrombosis. A case‐control study of plasma levels and DNA polymorphisms–the Leiden Thrombophilia Study (LETS), Thromb Haemost, 71, 719, 10.1055/s-0038-1642511 Kamphuisen, 1999, Increased levels of factor VIII and fibrinogen in patients with venous thrombosis are not caused by acute phase reactions, Thromb Haemost, 81, 680, 10.1055/s-0037-1614553 Green, 2010, Longitudinal assessment of fibrinogen in relation to subclinical cardiovascular disease: the CARDIA study, J Thromb Haemost, 8, 489, 10.1111/j.1538-7836.2009.03727.x Sabeti, 2005, Prognostic impact of fibrinogen in carotid atherosclerosis: nonspecific indicator of inflammation or independent predictor of disease progression?, Stroke, 36, 1400, 10.1161/01.STR.0000169931.96670.fc Staton, 2003, The role of fibrinogen and related fragments in tumour angiogenesis and metastasis, Expert Opin Biol Ther, 3, 1105, 10.1517/14712598.3.7.1105 Takeda, 1966, Studies of the metabolism and distribution of fibrinogen in healthy men with autologous 125I‐labeled fibrinogen, J Clin Invest, 45, 103, 10.1172/JCI105314 Doolittle, 1984, Fibrinogen and fibrin, Annu Rev Biochem, 53, 195, 10.1146/annurev.bi.53.070184.001211 Blomback, 1976, Disulfide bridges in NH2‐terminal part of human fibrinogen, Thromb Res, 8, 639, 10.1016/0049-3848(76)90245-0 Spraggon, 1997, Crystal structures of fragment D from human fibrinogen and its crosslinked counterpart from fibrin, Nature, 389, 455, 10.1038/38947 Kollman, 2009, Crystal structure of human fibrinogen, Biochemistry, 48, 3877, 10.1021/bi802205g Veklich, 1993, Carboxyl‐terminal portions of the α chains of fibrinogen and fibrin. Localization by electron microscopy and the effects of isolated αC fragments on polymerization, J Biol Chem, 268, 13577, 10.1016/S0021-9258(19)38688-0 Burton, 2006, Identification of an ordered compact structure within the recombinant bovine fibrinogen αC‐domain fragment by NMR, Biochemistry, 45, 2257, 10.1021/bi052380c Burton, 2007, NMR solution structure, stability, and interaction of the recombinant bovine fibrinogen αC‐domain fragment, Biochemistry, 46, 8550, 10.1021/bi700606v Tsurupa, 2009, Structure, stability, and interaction of the fibrin(ogen) αC‐domains, Biochemistry, 48, 12191, 10.1021/bi901640e Pechik, 2006, Structural basis for sequential cleavage of fibrinopeptides upon fibrin assembly, Biochemistry, 45, 3588, 10.1021/bi0525369 Mullin, 2000, Recombinant fibrinogen studies reveal that thrombin specificity dictates order of fibrinopeptide release, J Biol Chem, 275, 25239, 10.1074/jbc.M004142200 Blomback, 1996, Fibrinogen and fibrin–proteins with complex roles in hemostasis and thrombosis, Thromb Res, 83, 1, 10.1016/0049-3848(96)00111-9 Litvinov, 2005, Polymerization of fibrin: specificity, strength, and stability of knob‐hole interactions studied at the single‐molecule level, Blood, 106, 2944, 10.1182/blood-2005-05-2039 Chernysh, 2011, Visualization and identification of the structures formed during early stages of fibrin polymerization, Blood, 117, 4609, 10.1182/blood-2010-07-297671 Erickson, 1983, Electron microscopy of fibrinogen, its plasmic fragments and small polymers, Ann N Y Acad Sci, 408, 146, 10.1111/j.1749-6632.1983.tb23242.x Everse, 1998, Crystal structure of fragment double‐D from human fibrin with two different bound ligands, Biochemistry, 37, 8637, 10.1021/bi9804129 Weisel, 1986, Fibrin assembly. Lateral aggregation and the role of the two pairs of fibrinopeptides, Biophys J, 50, 1079, 10.1016/S0006-3495(86)83552-4 Weisel, 1993, The sequence of cleavage of fibrinopeptides from fibrinogen is important for protofibril formation and enhancement of lateral aggregation in fibrin clots, J Mol Biol, 232, 285, 10.1006/jmbi.1993.1382 Hogan, 2001, The formation of β fibrin requires a functional a site, Ann N Y Acad Sci, 936, 219, 10.1111/j.1749-6632.2001.tb03509.x Gorkun, 1994, Role of the αC domains of fibrin in clot formation, Biochemistry, 33, 6986, 10.1021/bi00188a031 Zhmurov, 2018, Atomic structural models of fibrin oligomers, Structure, 26, 857, 10.1016/j.str.2018.04.005 Laudano, 1978, Synthetic peptide derivatives that bind to fibrinogen and prevent the polymerization of fibrin monomers, Proc Natl Acad Sci USA, 75, 3085, 10.1073/pnas.75.7.3085 Yang, 2000, A model of fibrin formation based on crystal structures of fibrinogen and fibrin fragments complexed with synthetic peptides, Proc Natl Acad Sci USA, 97, 14156, 10.1073/pnas.97.26.14156 Hanss, 2001, A database for human fibrinogen variants, Ann N Y Acad Sci, 936, 89, 10.1111/j.1749-6632.2001.tb03495.x Blomback, 1968, Fibrinogen Detroit ‐ a molecular defect in the N‐terminal disulphide knot of human fibrinogen?, Nature, 218, 134, 10.1038/218134a0 Kudryk, 1976, Fibrinogen Detroit ‐ an abnormal fibrinogen with non‐functional NH2‐terminal polymerization domain, Thromb Res, 9, 25, 10.1016/0049-3848(76)90146-8 Nieuwenhuizen, 1981, Anticoagulant and calcium‐binding properties of high molecular weight derivatives of human fibrinogen, produced by plasmin (fragments X), Biochim Biophys Acta, 668, 81, 10.1016/0005-2795(81)90151-3 Duval, 2014, Roles of fibrin α‐ and γ‐chain specific cross‐linking by FXIIIa in fibrin structure and function, Thromb Haemost, 111, 842, 10.1160/TH13-10-0855 Mihalyi, 1968, Physicochemical studies of bovine fibrinogen. IV. Ultraviolet absorption and its relation to the structure of the molecule, Biochemistry, 7, 208, 10.1021/bi00841a026 Cardinali, 2010, Hydrodynamic and mass spectrometry analysis of nearly‐intact human fibrinogen, chicken fibrinogen, and of a substantially monodisperse human fibrinogen fragment X, Arch Biochem Biophys, 493, 157, 10.1016/j.abb.2009.10.008 Koppert, 1985, A monoclonal antibody, specific for human fibrinogen, fibrinopeptide A‐containing fragments and not reacting with free fibrinopeptide A, Blood, 66, 503, 10.1182/blood.V66.3.503.503 Van Ruijven‐Vermeer, 1978, Purification of rat fibrinogen and its constituent chains, Biochem J, 169, 653, 10.1042/bj1690653 Holm, 1985, Purification and characterization of 3 fibrinogens with different molecular weights obtained from normal human plasma, Thromb Res, 37, 165, 10.1016/0049-3848(85)90043-X Hurlet‐Jensen, 1983, The release of Bβ 1–42 from fibrinogen and fibrin by plasmin, Thromb Res, 29, 609, 10.1016/0049-3848(83)90215-3 Gorkun, 1997, The conversion of fibrinogen to fibrin: recombinant fibrinogen typifies plasma fibrinogen, Blood, 89, 4407, 10.1182/blood.V89.12.4407 Galanakis, 2015, Non‐enzymatic fibrinogen self‐assembly unveiled, J Thromb Haemost, 13, 581‐ Huang, 2013, The isolation of fibrinogen monomer dramatically influences fibrin polymerization, Thromb Res, 131, e258, 10.1016/j.thromres.2013.02.003 Raynal, 2013, Hydrodynamic characterization of recombinant human fibrinogen species, Thromb Res, 132, E48, 10.1016/j.thromres.2013.04.005 Bernocco, 2000, Polymerization of rod‐like macromolecular monomers studied by stopped‐flow, multiangle light scattering: set‐up, data processing, and application to fibrin formation, Biophys J, 79, 561, 10.1016/S0006-3495(00)76317-X Rocco, 2014, A comprehensive mechanism of fibrin network formation involving early branching and delayed single‐ to double‐strand transition from coupled time‐resolved X‐ray/light‐scattering detection, J Am Chem Soc, 136, 5376, 10.1021/ja5002955 Henschen, 1985, Genetically abnormal human fibrinogens ‐ a summary of 32 structurally elucidated variants, 107, 10.1016/B978-0-08-033215-4.50028-5 Hessel, 1986, Fibrinogen Aarhus–a new case of dysfibrinogenemia, Thromb Res, 42, 21, 10.1016/0049-3848(86)90193-3 Gron, 1988, Immunovisualization of fibrinogen Aα‐chain heterogeneity in normal plasma and plasma from patients with DIC or on streptokinase therapy, Thromb Res, 52, 413, 10.1016/0049-3848(88)90025-4 Weisel, 2001, The structure and function of the αC domains of fibrinogen, Ann N Y Acad Sci, 936, 312, 10.1111/j.1749-6632.2001.tb03517.x Weisel, 2005, Fibrinogen and fibrin, Adv Protein Chem, 70, 247, 10.1016/S0065-3233(05)70008-5 Litvinov, 2007, Direct evidence for specific interactions of the fibrinogen αC‐domains with the central E region and with each other, Biochemistry, 46, 9133, 10.1021/bi700944j Protopopova, 2015, Visualization of fibrinogen αC regions and their arrangement during fibrin network formation by high‐resolution AFM, J Thromb Haemost, 13, 570, 10.1111/jth.12785 Protopopova, 2017, Morphometric characterization of fibrinogen's αC regions and their role in fibrin self‐assembly and molecular organization, Nanoscale, 9, 13707, 10.1039/C7NR04413E Pederson, 2019, Oxidation‐induced destabilization of the fibrinogen αC‐domain dimer investigated by molecular dynamics simulations, Proteins, 87, 826, 10.1002/prot.25746 Cardinali, 2006, Identification of a new truncated form and deamidation products of fibrinopeptide B released by thrombin from human fibrinogen, Thromb Haemost, 96, 302, 10.1160/TH06-03-0138