Femtosecond (FS) laser vision correction procedure for moderate to high myopia: a prospective study of ReLEx® flex and comparison with a retrospective study of FS‐laser in situ keratomileusis

Acta Ophthalmologica - Tập 91 Số 4 - Trang 355-362 - 2013
Anders Højslet Vestergaard1,2, Anders Ivarsen1, S. Asp1, Jesper Hjortdal1
1Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark
2Department of Ophthalmology, Odense University Hospital, Odense, Denmark

Tóm tắt

Abstract.Purpose:  To present our initial clinical experience with ReLEx® flex (ReLEx) for moderate to high myopia. We compare efficacy, safety and corneal higher‐order aberrations after ReLEx with femtosecond laser in situ keratomileusis (FS‐LASIK).Methods:  Prospective study of ReLEx compared with a retrospective study of FS‐LASIK. ReLEx is a new keratorefractive procedure, where a stromal lenticule is cut by a femtosecond laser and manually extracted. Forty patients were treated with ReLEx on both eyes. A comparable group of 41 FS‐LASIK patients were retrospectively identified. Visual acuity, spherical equivalent (SE) and corneal tomography were measured before and 3 months after surgery.Results:  Preoperative SE averaged −7.50 ± 1.16 D (ReLEx) and −7.32 ± 1.09 D (FS‐LASIK). For all eyes, mean corrected distance visual acuity remained unchanged in both groups. For eyes with emmetropia as target refraction, 41% of ReLEx and 61% of FS‐LASIK eyes had an uncorrected distance visual acuity of logMAR ≤ 0.10 at day 1 after surgery, increasing to, respectively, 88% and 69% at 3 months. Mean SE was −0.06 ± 0.35 D 3 months after ReLEx and −0.53 ± 0.60 D after FS‐LASIK. The proportion of eyes within ±1.00 D after 3 months was 100% (ReLEx) and 85% (FS‐LASIK). For a 6.0‐mm pupil, corneal spherical aberrations increased significantly less in ReLEx than FS‐LASIK eyes.Conclusions:  ReLEx is an all‐in‐one femtosecond laser refractive procedure, and in this study, results were comparable to FS‐LASIK. Refractive predictability and corneal aberrations at 3 months seemed better than or equal to FS‐LASIK, whereas visual recovery after ReLEx was slower.

Từ khóa


Tài liệu tham khảo

10.1016/j.jcrs.2009.02.013

10.1007/s00347-010-2222-8

10.3928/1081597X-20090401-01

10.1007/s00417-009-1293-1

10.1097/ICO.0b013e31815a50bf

10.1001/archopht.126.11.1484

10.1159/000323814

Hjortdal JO, 2002, Prospective randomized study of corneal aberrations 1 year after radial keratotomy or photorefractive keratectomy, J Refract Surg, 18, 23, 10.3928/1081-597X-20020101-03

10.3928/1081-597X-19970701-16

10.1111/j.1755-3768.2008.01270.x

10.1097/00003226-200105000-00011

Medeiros FW, 2007, Wavefront analysis comparison of LASIK outcomes with the femtosecond laser and mechanical microkeratomes, J Refract Surg, 23, 880, 10.3928/1081-597X-20071101-03

10.1016/j.jcrs.2008.03.022

10.1016/j.jcrs.2008.05.033

10.1136/bjo.2009.174284

10.1016/j.jcrs.2010.07.033

10.1097/ICU.0b013e3281bd88a0

10.3928/1081-597X-20020901-30

10.1016/j.jcrs.2004.10.037