Fatty acid modifies Ca 2+ -dependent potassium channel activity in smooth muscle cells from the human aorta
Tóm tắt
By using the patch–clamp technique the effect of 2-decenoic acid (DA) on Ca
2+
-activated potassium (K
+
) channels in the membrane of smooth muscle cells from the human aorta was studied. In the presence of 0.5 μM Ca
2+
and 2 mM Mg
2+
on the cytoplasmic side of the membrane, a more than tenfold elevation in the probability of the channels being open (
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Tài liệu tham khảo
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