FUS stimulates microRNA biogenesis by facilitating co-transcriptional Drosha recruitment

Aman, 1996, Expression patterns of the human sarcoma-associated genes FUS and EWS and the genomic structure of FUS, Genomics, 37, 1, 10.1006/geno.1996.0513

Ballarino, 2009, Coupled RNA processing and transcription of intergenic primary microRNAs, Mol Cell Biol, 29, 5632, 10.1128/MCB.00664-09

Belly, 2005, Delocalization of the multifunctional RNA splicing factor TLS/FUS in hippocampal neurones: exclusion from the nucleus and accumulation in dendritic granules and spine heads, Neurosci Lett, 379, 152, 10.1016/j.neulet.2004.12.071

Belzil, 2009, Mutations in FUS cause FALS and SALS in French and French Canadian populations, Neurology, 73, 1176, 10.1212/WNL.0b013e3181bbfeef

Chakrabarti, 2002, Quantitative assessment of gene targeting in vitro and in vivo by the pancreatic transcription factor, Pdx1. Importance of chromatin structure in directing promoter binding, J Biol Chem, 277, 13286, 10.1074/jbc.M111857200

Chiò, 2009, Two Italian kindreds with familial amyotrophic lateral sclerosis due to FUS mutation, Neurobiol Aging, 30, 1272, 10.1016/j.neurobiolaging.2009.05.001

Denti, 2004, A new vector, based on the PolIII promoter of siRNAs in mammalian cells, Mol Ther, 10, 191, 10.1016/j.ymthe.2004.04.008

Denti, 2006, Chimeric adeno-associated virus/antisense U1 small nuclear RNA effectively rescues dystrophin synthesis and muscle function by local treatment of mdx mice, Hum Gene Ther, 17, 565, 10.1089/hum.2006.17.565

Dormann, 2010, ALS-associated fused in sarcoma (FUS) mutations disrupt Transortin-mediated nuclear import, EMBO J, 29, 2841, 10.1038/emboj.2010.143

Dye, 1999, Terminal exon definition occurs cotranscriptionally and promotes termination of RNA polymerase II, Mol Cell, 3, 371, 10.1016/S1097-2765(00)80464-5

Edbauer, 2010, Regulation of synaptic structure and function by FMRP-associated microRNAs miR-125b and miR-132, Neuron, 65, 373, 10.1016/j.neuron.2010.01.005

Figueroa, 2003, Role of HuR in skeletal myogenesis through coordinate regulation of muscle differentiation genes, Mol Cell Biol, 23, 4991, 10.1128/MCB.23.14.4991-5004.2003

Gregory, 2004, The microprocessor complex mediates the genesis of microRNAs, Nature, 432, 235, 10.1038/nature03120

Han, 2012, Cell-free formation of RNA granules: bound RNAs identify features and components of cellular assemblies, Cell, 149, 768, 10.1016/j.cell.2012.04.016

Hoell, 2011, RNA targets of wild-type and mutant FET family proteins, Nat Struct Mol Biol, 18, 1428, 10.1038/nsmb.2163

Iko, 2004, Domain architectures and characterization of an RNA-binding protein, TLS, J Biol Chem, 279, 44834, 10.1074/jbc.M408552200

Ito, 2011, Nuclear transport impairment of amyotrophic lateral sclerosis-linked mutations in FUS/TLS, Ann Neurol, 69, 152, 10.1002/ana.22246

Kwiatkowski, 2009, Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis, Science, 323, 1205, 10.1126/science.1166066

Lagier-Tourenne, 2009, Rethinking ALS: the FUS about TDP-43, Cell, 136, 1001, 10.1016/j.cell.2009.03.006

Lagier-Tourenne, 2010, TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration, Hum Mol Genet, 19, R46, 10.1093/hmg/ddq137

Laneve, 2007, The interplay between microRNAs and the neurotrophin receptor tropomyosin-related kinase C controls proliferation of human neuroblastoma cells, Proc Natl Acad Sci USA, 104, 7957, 10.1073/pnas.0700071104

Laneve, 2010, A minicircuitry involving REST and CREB controls miR-9-2 expression during human neuronal differentiation, Nucleic Acids Res, 38, 6895, 10.1093/nar/gkq604

Law, 2006, TLS, EWS and TAF15: a model for transcriptional integration of gene expression, Brief Funct Genomic Proteomic, 5, 8, 10.1093/bfgp/ell015

Michlewski, 2008, Posttranscriptional regulation of miRNAs harboring conserved terminal loops, Mol Cell, 32, 383, 10.1016/j.molcel.2008.10.013

Michlewski, 2010, Stimulation of pri-miR-18a processing by hnRNP A1, Adv Exp Med Biol, 700, 28, 10.1007/978-1-4419-7823-3_3

Morlando, 2004, Coupling between snoRNP assembly and 3' processing controls box C/D snoRNA biosynthesis in yeast, EMBO J, 23, 2392, 10.1038/sj.emboj.7600254

Morlando, 2008, Primary microRNA transcripts are processed co-transcriptionally, Nat Struct Mol Biol, 15, 902, 10.1038/nsmb.1475

Packer, 2008, The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington's disease, J Neurosci, 28, 14341, 10.1523/JNEUROSCI.2390-08.2008

Pathania, 2012, miR-132 enhances dendritic morphogenesis, spine density, synaptic integration, and survival of newborn olfactory bulb neurons, PLoS ONE, 7, e38174, 10.1371/journal.pone.0038174

Polymenidou, 2012, Misregulated RNA processing in amyotrophic lateral sclerosis, Brain Res, 1462, 3, 10.1016/j.brainres.2012.02.059

Riggi, 2007, Sarcomas: genetics, signalling, and cellular origins, J Pathol, 213, 4, 10.1002/path.2209

Song, 2012, Promoter-associated noncoding RNA from the CCND1 promoter, Methods Mol Biol, 809, 609, 10.1007/978-1-61779-376-9_39

Tan, 2009, The TET family of proteins: functions and roles in disease, J Mol Cell Biol, 1, 82, 10.1093/jmcb/mjp025

Tan, 2012, TLS/FUS (translocated in liposarcoma/fused in sarcoma) regulates target gene transcription via single-stranded DNA response elements, Proc Natl Acad Sci USA, 109, 6030, 10.1073/pnas.1203028109

Vance, 2009, Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6, Science, 323, 1208, 10.1126/science.1165942

Wang, 2008, Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription, Nature, 454, 126, 10.1038/nature06992

Yang, 2010, Fused in sarcoma/translocated in liposarcoma: a multifunctional DNA/RNA binding protein, Int J Biochem Cell Biol, 42, 1408, 10.1016/j.biocel.2010.06.003

Yamamoto, 2011, The elimination of accumulated and aggregated proteins: a role for aggrephagy in neurodegeneration, Neurobiol Dis, 43, 17, 10.1016/j.nbd.2010.08.015

Zinszner, 1997, TLS (FUS) binds RNA in vivo and engages in nucleo-cytoplasmic shuttling, J Cell Sci, 110, 1741, 10.1242/jcs.110.15.1741