Sự gia tăng của Prevotella copri trong ruột tương quan với sự nhạy cảm cao hơn đối với bệnh viêm khớp
Tóm tắt
Viêm khớp dạng thấp (RA) là một bệnh tự miễn hệ thống phổ biến, do sự kết hợp của các yếu tố di truyền và môi trường gây ra. Các mô hình động vật gợi ý rằng vi khuẩn ruột có vai trò trong việc hỗ trợ phản ứng miễn dịch hệ thống cần thiết cho sự viêm khớp. Trong nghiên cứu này, chúng tôi thực hiện giải trình tự 16S trên 114 mẫu phân từ bệnh nhân viêm khớp dạng thấp và các đối chứng, và giải trình tự shotgun trên một tập hợp con gồm 44 mẫu như vậy. Chúng tôi xác định sự hiện diện của
Từ khóa
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