Mở Rộng Quy Mô: Nhiều Vai Trò Của Hormone Tập Trung Melanin (MCH) Trong Việc Điều Hòa Cân Bằng Năng Lượng Và Các Chức Năng Sinh Học Khác

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Della-Zuana, 2002, Acute and chronic administration of melanin-concentrating hormone enhances food intake and body weight in Wistar and Sprague-Dawley rats., Int J Obes Relat Metab Disord, 26, 1289, 10.1038/sj.ijo.0802079

Gomori, 2003, Chronic intracerebroventricular infusion of MCH causes obesity in mice, Melanin-concentrating hormone. Am J Physiol Endocrinol Metab, 284, E583, 10.1152/ajpendo.00350.2002

Bjursell, 2006, Melanin-concentrating hormone receptor 1 deficiency increases insulin sensitivity in obese leptin-deficient mice without affecting body weight., Diabetes, 55, 725, 10.2337/diabetes.55.03.06.db05-1302

Kinoshita, 2001, Transgenic medaka overexpressing a melanin-concentrating hormone exhibit lightened body color but no remarkable abnormality., Mar Biotechnol (NY), 3, 536, 10.1007/s10126-001-0061-Y

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Maekawa, 2004, Leptin resistance and enhancement of feeding facilitation by melanin-concentrating hormone in mice lacking bombesin receptor subtype-3., Diabetes, 53, 570, 10.2337/diabetes.53.3.570

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Sergeyev, 2000, Effect of 2-mercaptoacetate and 2-deoxy-D-glucose administration on the expression of NPY, AGRP, POMC, MCH and hypocretin/orexin in the rat hypothalamus., Neuroreport, 11, 117, 10.1097/00001756-200001170-00023

Hintermann, 1999, Synthesis and characterization of new radioligands for the mammalian melanin-concentrating hormone (MCH) receptor., J Recept Signal Transduct Res, 19, 411, 10.3109/10799899909036661

Kokkotou, 2000, Characterization of [Phe(13), Tyr(19)]-MCH analog binding activity to the MCH receptor., Neuropeptides, 34, 240, 10.1054/npep.2000.0821

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Saito, 2005, Arginine residue 155 in the second intracellular loop plays a critical role in rat melanin-concentrating hormone receptor 1 activation., Endocrinology, 146, 3452, 10.1210/en.2005-0115

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Hervieu, 2000, The distribution of the mRNA and protein products of the melanin-concentrating hormone (MCH) receptor gene, slc-1, in the central nervous system of the rat., Eur J Neurosci, 12, 1194, 10.1046/j.1460-9568.2000.00008.x

Saito, 2000, Melanin-concentrating hormone receptor: an orphan receptor fits the key., Trends Endocrinol Metab, 11, 299, 10.1016/S1043-2760(00)00290-3

Bradley, 2000, Melanin-concentrating hormone regulates leptin synthesis and secretion in rat adipocytes., Diabetes, 49, 1073, 10.2337/diabetes.49.7.1073

An, 2001, Identification and characterization of a melanin-concentrating hormone receptor., Proc Natl Acad Sci USA, 98, 7576, 10.1073/pnas.131200698

Hill, 2001, Molecular cloning and functional characterization of MCH2, a novel human MCH receptor., J Biol Chem, 276, 20125, 10.1074/jbc.M102068200

Mori, 2001, Cloning of a novel G protein-coupled receptor, SLT, a subtype of the melanin-concentrating hormone receptor., Biochem Biophys Res Commun, 283, 1013, 10.1006/bbrc.2001.4893

Rodriguez, 2001, Cloning and molecular characterization of the novel human melanin-concentrating hormone receptor MCH2., Mol Pharmacol, 60, 632

Sailer, 2001, Identification and characterization of a second melanin-concentrating hormone receptor, MCH-2R., Proc Natl Acad Sci USA, 98, 7564, 10.1073/pnas.121170598

Wang, 2001, Identification and pharmacological characterization of a novel human melanin-concentrating hormone receptor, mch-r2., J Biol Chem, 276, 34664, 10.1074/jbc.M102601200

Schlumberger, 2002, Expression of receptors for melanin-concentrating hormone (MCH) in different tissues and cell lines., J Recept Signal Transduct Res, 22, 509, 10.1081/RRS-120014618

Fried, 2002, Cloning and characterization of rhesus monkey MCH-R1 and MCH-R2., Peptides, 23, 1401, 10.1016/S0196-9781(02)00077-3

Tan, 2002, Melanin-concentrating hormone receptor subtypes 1 and 2: species-specific gene expression., Genomics, 79, 785, 10.1006/geno.2002.6771

Wermter, 2005, Mutation analysis of the MCHR1 gene in human obesity., Eur J Endocrinol, 152, 851, 10.1530/eje.1.01917

Hawes, 2004, Identification and characterization of single-nucleotide polymorphisms in MCH-R1 and MCH-R2., Obes Res, 12, 1327, 10.1038/oby.2004.167

Gibson, 2004, Melanin-concentrating hormone receptor mutations and human obesity: functional analysis., Obes Res, 12, 743, 10.1038/oby.2004.89

Handlon, 2006, Melanin-concentrating hormone-1 receptor antagonists for the treatment of obesity., J Med Chem, 49, 4017, 10.1021/jm058239j

Palani, 2005, Biaryl ureas as potent and orally efficacious melanin concentrating hormone receptor 1 antagonists for the treatment of obesity., J Med Chem, 48, 4746, 10.1021/jm0503852

Borowsky, 2002, Antidepressant, anxiolytic and anorectic effects of a melanin-concentrating hormone-1 receptor antagonist., Nat Med [Erratum (2002) 8:1039], 8, 825

Chaki, 2005, Anxiolytic- and antidepressant-like profile of ATC0065 and ATC0175: nonpeptidic and orally active melanin-concentrating hormone receptor 1 antagonists., J Pharmacol Exp Ther, 313, 831, 10.1124/jpet.104.081711

Mashiko, 2005, Antiobesity effect of a melanin-concentrating hormone 1 receptor antagonist in diet-induced obese mice., Endocrinology, 146, 3080, 10.1210/en.2004-1150

Pol, 2004, Physiological properties of hypothalamic MCH neurons identified with selective expression of reporter gene after recombinant virus infection., Neuron, 42, 635, 10.1016/S0896-6273(04)00251-X

Eggermann, 2003, The wake-promoting hypocretin-orexin neurons are in an intrinsic state of membrane depolarization., J Neurosci, 23, 1557, 10.1523/JNEUROSCI.23-05-01557.2003

Bayer, 2005, Opposite effects of noradrenaline and acetylcholine upon hypocretin/orexin versus melanin concentrating hormone neurons in rat hypothalamic slices., Neuroscience, 130, 807, 10.1016/j.neuroscience.2004.10.032

Burdakov, 2005, Physiological changes in glucose differentially modulate the excitability of hypothalamic melanin-concentrating hormone and orexin neurons in situ., J Neurosci, 25, 2429, 10.1523/JNEUROSCI.4925-04.2005

Gao, 2002, Melanin-concentrating hormone depresses L-, N-, and P/Q-type voltage-dependent calcium channels in rat lateral hypothalamic neurons., J Physiol, 542, 273, 10.1113/jphysiol.2002.019372

Gao, 2001, Melanin concentrating hormone depresses synaptic activity of glutamate and GABA neurons from rat lateral hypothalamus., J Physiol, 533, 237, 10.1111/j.1469-7793.2001.0237b.x

Davidowa, 2002, Hypothalamic ventromedial and arcuate neurons of normal and postnatally overnourished rats differ in their responses to melanin-concentrating hormone., Regul Pept, 108, 103, 10.1016/S0167-0115(02)00153-2

Davidowa, 2003, Altered responses to orexigenic (AGRP, MCH) and anorexigenic (α-MSH, CART) neuropeptides of paraventricular hypothalamic neurons in early postnatally overfed rats., Eur J Neurosci, 18, 613, 10.1046/j.1460-9568.2003.02789.x

Varas, 2002, Melanin concentrating hormone increase hippocampal synaptic transmission in the rat., Peptides, 23, 151, 10.1016/S0196-9781(01)00591-5

Korotkova, 2003, Excitation of ventral tegmental area dopaminergic and nondopaminergic neurons by orexins/hypocretins., J Neurosci, 23, 7, 10.1523/JNEUROSCI.23-01-00007.2003

Gonzalez, 1997, Stimulatory effect of melanin-concentrating hormone on luteinising hormone release., Neuroendocrinology, 66, 254, 10.1159/000127246

Williamson-Hughes, 2005, Melanin concentrating hormone (MCH): a novel neural pathway for regulation of GnRH neurons., Brain Res, 1041, 117, 10.1016/j.brainres.2004.11.066

Murray, 2000, The effect of leptin on luteinizing hormone release is exerted in the zona incerta and mediated by melanin-concentrating hormone., J Neuroendocrinol, 12, 1133, 10.1046/j.1365-2826.2000.00577.x

Chiocchio, 2001, Melanin-concentrating hormone stimulates the release of luteinizing hormone-releasing hormone and gonadotropins in the female rat acting at both median eminence and pituitary levels., Biol Reprod, 64, 1466, 10.1095/biolreprod64.5.1466

Kennedy, 2001, Melanin-concentrating hormone (MCH) suppresses thyroid stimulating hormone (TSH) release, in vivo and in vitro, via the hypothalamus and the pituitary., Endocrinology, 142, 3265, 10.1210/endo.142.7.8374

Kennedy, 2003, Effect of direct injection of melanin-concentrating hormone into the paraventricular nucleus: further evidence for a stimulatory role in the adrenal axis via SLC-1., J Neuroendocrinol, 15, 268, 10.1046/j.1365-2826.2003.00997.x

Gonzalez, 1998, Behavioral effects of neuropeptide E-I (NEI) in the female rat: interactions with α-MSH, MCH and dopamine., Peptides, 19, 1007, 10.1016/S0196-9781(98)00045-X

Sanchez, 1997, Melanin-concentrating hormone (MCH) antagonizes the effects of α-MSH and neuropeptide E-I on grooming and locomotor activities in the rat., Peptides, 18, 393, 10.1016/S0196-9781(96)00327-0

Marsh, 2002, Melanin-concentrating hormone 1 receptor-deficient mice are lean, hyperactive, and hyperphagic and have altered metabolism., Proc Natl Acad Sci USA, 99, 3240, 10.1073/pnas.052706899

Chen, 2002, Targeted disruption of the melanin-concentrating hormone receptor-1 results in hyperphagia and resistance to diet-induced obesity., Endocrinology, 143, 2469, 10.1210/endo.143.7.8903

Zhou, 2005, Enhanced running wheel activity of both Mch1r- and Pmch-deficient mice., Regul Pept, 124, 53, 10.1016/j.regpep.2004.06.026

Kokkotou, 2005, Mice with MCH ablation resist diet-induced obesity through strain-specific mechanisms, Am J Physiol Regul Integr Comp Physiol, 289, R117, 10.1152/ajpregu.00861.2004

Georgescu, 2005, The hypothalamic neuropeptide melanin-concentrating hormone acts in the nucleus accumbens to modulate feeding behavior and forced-swim performance., J Neurosci, 25, 2933, 10.1523/JNEUROSCI.1714-04.2005

Smith, 2005, Mesolimbic dopamine super-sensitivity in melanin-concentrating hormone-1 receptor-deficient mice., J Neurosci, 25, 914, 10.1523/JNEUROSCI.4079-04.2005

Monzon, 1999, Response to novelty after i.c.v. injection of melanin-concentrating hormone (MCH) in rats., Physiol Behav, 67, 813, 10.1016/S0031-9384(99)00117-1

Kela, 2003, Behavioural analysis of melanin-concentrating hormone in rats: evidence for orexigenic and anxiolytic properties., Regul Pept, 114, 109, 10.1016/S0167-0115(03)00114-9

Roy, 2006, Genetic inactivation of melanin-concentrating hormone receptor subtype 1 (MCHR1) in mice exerts anxiolytic-like behavioral effects., Neuropsychopharmacology, 31, 112, 10.1038/sj.npp.1300805

Hervieu, 1995, Pro-melanin concentrating hormone messenger ribonucleic acid and peptides expression in peripheral tissues of the rat., Neuroendocrinology, 61, 348, 10.1159/000126857

Verlaet, 2002, Human immune cells express ppMCH mRNA and functional MCHR1 receptor., FEBS Lett, 527, 205, 10.1016/S0014-5793(02)03232-5

Hoogduijn, 2002, Melanin-concentrating hormone and its receptor are expressed and functional in human skin., Biochem Biophys Res Commun, 296, 698, 10.1016/S0006-291X(02)00932-4

Tadayyon, 2000, Expression of melanin-concentrating hormone receptors in insulin-producing cells: MCH stimulates insulin release in RINm5F and CRI-G1 cell-lines., Biochem Biophys Res Commun, 275, 709, 10.1006/bbrc.2000.3357

Colombo, 2003, Effects of ghrelin and other neuropeptides (CART, MCH, orexin A and B, and GLP-1) on the release of insulin from isolated rat islets., Pancreas, 27, 161, 10.1097/00006676-200308000-00009

Saito, 2001, Endogenous melanin-concentrating hormone receptor SLC-1 in human melanoma SK-MEL-37 cells., Biochem Biophys Res Commun, 289, 44, 10.1006/bbrc.2001.5926

Kemp, 2002, The melanin-concentrating hormone receptor 1, a novel target of autoantibody responses in vitiligo., J Clin Invest, 109, 923, 10.1172/JCI0214643

Bradley, 2002, Melanin-concentrating hormone activates signaling pathways in 3T3–L1 adipocytes, Am J Physiol Endocrinol Metab, 283, E584, 10.1152/ajpendo.00161.2002

Saito, 2004, Properties of rat melanin-concentrating hormone receptor 1 internalization., Peptides, 25, 1597, 10.1016/j.peptides.2004.03.026

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