Exercise prevents hyperhomocysteinemia in a dietary folate-restricted mouse model

Nutrition Research - Tập 33 - Trang 487-493 - 2013
Joshua C. Neuman1,2, Kelsey A. Albright1, Kevin L. Schalinske1,2
1Department of Food Science and Human Nutrition, Iowa State University, Ames, Iowa, 50011
2Interdepartmental Graduate Program in Nutritional Sciences, Iowa State University, Ames, Iowa 50011

Tài liệu tham khảo

Blount, 1997, Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage, Proc Natl Acad Sci USA, 94, 3290, 10.1073/pnas.94.7.3290 McCaddon, 1998, Total serum homocysteine in senile dementia of Alzheimer type, Int J Geriatr Psychiatry, 13, 235, 10.1002/(SICI)1099-1166(199804)13:4<235::AID-GPS761>3.0.CO;2-8 Seller, 1984, Periconceptional vitamin supplementation and the prevention of neural tube defects in south-east England and Northern Ireland, J Med Genet, 21, 325, 10.1136/jmg.21.5.325 Wald, 2002, Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis, BMJ, 325, 1202, 10.1136/bmj.325.7374.1202 Clarke, 1991, Hyperhomocysteinemia: an independent risk factor for vascular disease, N Engl J Med, 324, 1149, 10.1056/NEJM199104253241701 Williams, 2007, New insights into the regulation of methyl group and homocysteine metabolism, J Nutr, 137, 311, 10.1093/jn/137.2.311 Bailey, 2000, Training in hypoxia: modulation of metabolic and cardiovascular risk factors in men, Med Sci Sports Exerc, 32, 1058, 10.1097/00005768-200006000-00004 De Cree, 1999, Influence of exercise and menstrual cycle phase on plasma homocyst(e)ine levels in young women—a prospective study, Scand J Med Sci Sports, 9, 272, 10.1111/j.1600-0838.1999.tb00245.x de Jong, 2001, Nutrient-dense foods and exercise in frail elderly: effects on B vitamins, homocysteine, methylmalonic acid, and neuropsychological functioning, Am J Clin Nutr, 73, 338, 10.1093/ajcn/73.2.338 Duncan, 2004, Effects of exercise on emerging and traditional cardiovascular risk factors, Prev Med, 39, 894, 10.1016/j.ypmed.2004.03.012 Gaume, 2005, Physical training decreases total plasma homocysteine and cysteine in middle-aged subjects, Ann Nutr Metab, 49, 125, 10.1159/000085536 Herrmann, 2003, Homocysteine increases during endurance exercise, Clin Chem Lab Med, 41, 1518, 10.1515/CCLM.2003.233 Konig, 2003, Influence of training volume and acute physical exercise on the homocysteine levels in endurance-trained men: interactions with plasma folate and vitamin B12, Ann Nutr Metab, 47, 114, 10.1159/000070032 Randeva, 2002, Exercise decreases plasma total homocysteine in overweight young women with polycystic ovary syndrome, J Clin Endocrinol Metab, 87, 4496, 10.1210/jc.2001-012056 Wright, 1998, Effect of acute exercise on plasma homocysteine, J Sports Med Phys Fitness, 38, 262 Husemoen, 2004, Effect of lifestyle factors on plasma total homocysteine concentrations in relation to MTHFR(C677T) genotype. Inter99 (7), Eur J Clin Nutr, 58, 1142, 10.1038/sj.ejcn.1601942 Joubert, 2006, Exercise, nutrition, and homocysteine, Int J Sport Nutr Exerc Metab, 16, 341, 10.1123/ijsnem.16.4.341 Ahlborg, 1974, Substrate turnover during prolonged exercise in man. Splanchnic and leg metabolism of glucose, free fatty acids, and amino acids, J Clin Invest, 53, 1080, 10.1172/JCI107645 Blomstrand, 2001, BCAA intake affects protein metabolism in muscle after but not during exercise in humans, Am J Physiol Endocrinol Metab, 281, E365, 10.1152/ajpendo.2001.281.2.E365 Dohm, 1981, Influence of exercise on free amino acid concentrations in rat tissues, J Appl Physiol, 50, 41, 10.1152/jappl.1981.50.1.41 Mourtzakis, 2006, Carbohydrate metabolism during prolonged exercise and recovery: interactions between pyruvate dehydrogenase, fatty acids, and amino acids, J Appl Physiol, 100, 1822, 10.1152/japplphysiol.00571.2005 Woolf, 2006, B-vitamins and exercise: does exercise alter requirements?, Int J Sport Nutr Exerc Metab, 16, 453, 10.1123/ijsnem.16.5.453 Nieman, 2006, Folate status modulates the induction of hepatic glycine N-methyltransferase and homocysteine metabolism in diabetic rats, Am J Physiol Endocrinol Metab, 291, E1235, 10.1152/ajpendo.00237.2006 Nieman, 2004, Modulation of methyl group metabolism by streptozotocin-induced diabetes and all-trans-retinoic acid, J Biol Chem, 279, 45708, 10.1074/jbc.M408664200 Rowling, 2003, Retinoic acid and glucocorticoid treatment induce hepatic glycine N-methyltransferase and lower plasma homocysteine concentrations in rats and rat hepatoma cells, J Nutr, 133, 3392, 10.1093/jn/133.11.3392 Williams, 2008, Type 1 diabetes leads to tissue-specific DNA hypomethylation in male rats, J Nutr, 138, 2064, 10.3945/jn.108.094144 Bailey, 1999, Polymorphisms of methylenetetrahydrofolate reductase and other enzymes: metabolic significance, risks and impact on folate requirement, J Nutr, 129, 919, 10.1093/jn/129.5.919 Rowling, 2002, Hepatic glycine N-methyltransferase is up-regulated by excess dietary methionine in rats, J Nutr, 132, 2545, 10.1093/jn/132.9.2545 Ubbink, 1991, Rapid high-performance liquid chromatographic assay for total homocysteine levels in human serum, J Chromatogr, 565, 441, 10.1016/0378-4347(91)80407-4 Williams, 2012, Tissue-specific alterations of methyl group metabolism with DNA hypermethylation in the Zucker (type 2) diabetic fatty rat, Diabetes Metab Res Rev, 28, 123, 10.1002/dmrr.1281 Garrow, 1996, Purification, kinetic properties, and cDNA cloning of mammalian betaine-homocysteine methyltransferase, J Biol Chem, 271, 22831, 10.1074/jbc.271.37.22831 Keating, 1985, Demonstration of methionine synthetase in intestinal mucosal cells of the rat, Clin Sci (Lond), 69, 287, 10.1042/cs0690287 Snedecor, 1980 Mora, 2007, Physical activity and reduced risk of cardiovascular events: potential mediating mechanisms, Circulation, 116, 2110, 10.1161/CIRCULATIONAHA.107.729939 Ueland, 2000, The controversy over homocysteine and cardiovascular risk, Am J Clin Nutr, 72, 324, 10.1093/ajcn/72.2.324 Dayal, 2001, Endothelial dysfunction and elevation of S-adenosylhomocysteine in cystathionine beta-synthase-deficient mice, Circ Res, 88, 1203, 10.1161/hh1101.092180 Wilson, 2003, Effect of mechanical ventilation on carotid artery thrombosis induced by photochemical injury in mice, J Thromb Haemost, 1, 2669, 10.1111/j.1538-7836.2003.00482.x Bonaa, 2006, Homocysteine lowering and cardiovascular events after acute myocardial infarction, N Engl J Med, 354, 1578, 10.1056/NEJMoa055227 den Heijer, 2007, Homocysteine lowering by B vitamins and the secondary prevention of deep vein thrombosis and pulmonary embolism: a randomized, placebo-controlled, double-blind trial, Blood, 109, 139, 10.1182/blood-2006-04-014654 Jamison, 2007, Effect of homocysteine lowering on mortality and vascular disease in advanced chronic kidney disease and end-stage renal disease: a randomized controlled trial, JAMA, 298, 1163, 10.1001/jama.298.10.1163 Lonn, 2006, Homocysteine lowering with folic acid and B vitamins in vascular disease, N Engl J Med, 354, 1567, 10.1056/NEJMoa060900 McCully, 2007, Homocysteine, vitamins, and vascular disease prevention, Am J Clin Nutr, 86, 1563S, 10.1093/ajcn/86.5.1563S McNulty, 2008, Homocysteine, B-vitamins and CVD, Proc Nutr Soc, 67, 232, 10.1017/S0029665108007076 Rodionov, 2008, The homocysteine paradox, Arterioscler Thromb Vasc Biol, 28, 1031, 10.1161/ATVBAHA.108.164830 Ohuchi, 2009, High casein diet decreases plasma homocysteine concentration in rats, J Nutr Sci Vitaminol (Tokyo), 55, 22, 10.3177/jnsv.55.22 Allen, 1993, Serum betaine, N,N-dimethylglycine and N-methylglycine levels in patients with cobalamin and folate deficiency and related inborn errors of metabolism, Metabolism, 42, 1448, 10.1016/0026-0495(93)90198-W Delgado-Reyes, 2001, Immunohistochemical detection of betaine-homocysteine S-methyltransferase in human, pig, and rat liver and kidney, Arch Biochem Biophys, 393, 184, 10.1006/abbi.2001.2474 Garibotto, 2009, The kidney is the major site of S-adenosylhomocysteine disposal in humans, Kidney Int, 76, 293, 10.1038/ki.2009.117 Jacobs, 1998, Effects of streptozotocin-induced diabetes and of insulin treatment on homocysteine metabolism in the rat, Diabetes, 47, 1967, 10.2337/diabetes.47.12.1967 Jacobs, 2001, Hyperglucagonemia in rats results in decreased plasma homocysteine and increased flux through the transsulfuration pathway in liver, J Biol Chem, 276, 43740, 10.1074/jbc.M107553200 Ratnam, 2002, Hormonal regulation of cystathionine β-synthase expression in liver, J Biol Chem, 277, 42912, 10.1074/jbc.M206588200 Ratnam, 2006, Effects of diabetes and insulin on betaine-homocysteine S-methyltransferase expression in rat liver, Am J Physiol Endocrinol Metab, 290, E933, 10.1152/ajpendo.00498.2005 Stipanuk, 2004, Sulfur amino acid metabolism: pathways for production and removal of homocysteine and cysteine, Annu Rev Nutr, 24, 539, 10.1146/annurev.nutr.24.012003.132418 Gaume, 2005, Effect of a swim training on homocysteine and cysteine levels in rats, Amino Acids, 28, 337, 10.1007/s00726-004-0147-8