Exercise in the Metabolic Syndrome

Oxidative Medicine and Cellular Longevity - Tập 2012 - Trang 1-13 - 2012
Saeid Golbidi1, Azam Mesdaghinia2, Ismail Laher1
1Department of Anesthesiology, Pharmacology and Therapeutics, Faculty of Medicine, The University of British Columbia, Vancouver, BC, Canada V6T 1Z3
2Physiology Research Center, Kashan University of Medical Sciences and Health Services, Kashan 87155/111, Iran

Tóm tắt

The metabolic syndrome is a clustering of obesity, diabetes, hyperlipidemia, and hypertension that is occurring in increasing frequency across the global population. Although there is some controversy about its diagnostic criteria, oxidative stress, which is defined as imbalance between the production and inactivation of reactive oxygen species, has a major pathophysiological role in all the components of this disease. Oxidative stress and consequent inflammation induce insulin resistance, which likely links the various components of this disease. We briefly review the role of oxidative stress as a major component of the metabolic syndrome and then discuss the impact of exercise on these pathophysiological pathways. Included in this paper is the effect of exercise in reducing fat-induced inflammation, blood pressure, and improving muscular metabolism.

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Oxidative Medicine and Cellular Longevity

Tập 2012

1-13

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