Ex-vivo absorption study of lysine R-lipoate salt, a new pharmaceutical form of R-ALA

Balamurugan, 2005, Biotin uptake by human proximal tubular epithelial cells: cellular and molecular aspects, Am. J. Physiol. Ren. Physiol., 288, F823, 10.1152/ajprenal.00375.2004

Bareket, 2013, Riluzole increases the rate of glucose transport in L6 myotubes and NSC-34 motor neuron-like cells via AMPK pathway activation, Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 14, 434, 10.3109/21678421.2013.808226

Bramanti, 2010, α-Lipoic acid modulates GFAP, vimentin, nestin, cyclin D1 and MAP-kinase expression in astroglial cell cultures, Neurochem. Res., 35, 2070, 10.1007/s11064-010-0256-6

Breithaupt-Grogler, 1999, Dose-proportionality of oral thioctic acid–coincidence of assessments via pooled plasma and individual data, Eur. J. Pharm. Sci., 8, 57, 10.1016/S0928-0987(98)00061-X

Brookes, 1983, Proof that the absolute configuration of natural α-lipoic from S-malic acid, J. Chem. Soc. Chem. Commun., 19, 1051, 10.1039/C39830001051

Costa, 2013, Neovascularization in diabetes and its complications. Unraveling the angiogenic paradox, Life Sci., 92, 1037, 10.1016/j.lfs.2013.04.001

Derosa, 2016, Clinical trial about a food supplement containing α-lipoic acid on oxidative stress markers in type 2 diabetic patients, Int. J. Mol. Sci., 17, 2, 10.3390/ijms17111802

Frölich, 2004, (r)-, but not (s)-alpha lipoic acid stimulates deficient brain pyruvate dehydrogenase complex in vascular dementia, but not in Alzheimer dementia, J. Neural Transm., 111, 295, 10.1007/s00702-003-0043-5

Gębka, 2014, Effect of the administration of alpha-lipoic acid on contrast sensitivity in patients with type 1 and type 2 diabetes, Mediat. Inflamm., 1, 10.1155/2014/131538

Gumus, 2010, The role of oxidative stress and effect of alpha-lipoic acid in reexpansion pulmonary edema – an experimental study, Arch. Med. Sci., 6, 848, 10.5114/aoms.2010.19290

Gurunath, 2014, Enhanced solubility and intestinal absorption of candesartan cilexetil solid dispersions using everted rat intestinal sacs, Saudi Pharm J., 22, 246, 10.1016/j.jsps.2013.03.006

Hu, 2017, Alpha-lipoic acid suppresses P2X receptor activities and visceral hypersensitivity to colorectal distention in diabetic rats, Sci. Rep., 7, 3928, 10.1038/s41598-017-04283-7

Hwang, 2016, Inhibitory effects of α-lipoic acid on oxidative stress-induced adipogenesis in orbital fibroblasts from patients with graves ophthalmopathy, Medicine, 95, 10.1097/MD.0000000000002497

Jeong, 2016, Effect of alpha-lipoic acid on radiation-induced small intestine injury in mice, Oncotarget, 7, 15105, 10.18632/oncotarget.7874

Lassoued, 2011, Comparative study of two in vitro methods for assessing drug absorption: Sartorius SM 16750 apparatus versus everted gut sac, J. Pharm. Pharmaceut. Sci., 14, 117, 10.18433/J3GC7R

Li, 2015, Effect of lipoic acid combined with paclitaxel on breast cancer cells, Genet. Mol. Res., 22, 17934, 10.4238/2015.December.22.18

Li, 2016, α-Lipoic acid exerts neuroprotective effects on neuronal cells by upregulating the expression of PCNA via the P53 pathway in neurodegenerative conditions, Mol. Med. Rep., 14, 4360, 10.3892/mmr.2016.5754

Lii, 2010, Sulforaphane and alpha-lipoic acid upregulate the expression of the pi class of glutathione S-transferase through c-jun and Nrf2 activation, J. Nutr., 140, 885, 10.3945/jn.110.121418

Moon, 2016, Chemopreventive effects of alpha lipoic acid on obesity-related cancers, Ann. Nutr. Metab., 68, 137, 10.1159/000443994

Morikawa, 2001, Do mammalian cells synthesize lipoic acid? Identification of a mouse cDNA encoding a lipoic acid synthase located in mitochondria, FEBS Lett., 498, 16, 10.1016/S0014-5793(01)02469-3

Park, 2014, The stimulatory effect of essential fatty acids on glucose uptake involves both Akt and AMPK activation in C2C12 skeletal muscle cells, Korean J Physiol Pharmacol., 18, 255, 10.4196/kjpp.2014.18.3.255

Prasad, 1998, Cloning and functional expression of a cDNA encoding a mammalian sodium-dependent vitamin transporter mediating the uptake of pantothenate, biotin, and lipoate, J. Biol. Chem., 273, 7501, 10.1074/jbc.273.13.7501

Reed, 1998, From lipoic acid to multi-enzyme complexes, Protein Sci., 7, 220, 10.1002/pro.5560070125

Salinthone, 2010, Lipoic acid attenuates inflammation via cAMP and protein kinase a signaling, PLoS One, 5, 10.1371/journal.pone.0013058

Shay, 2008, Is alpha-lipoic acid a scavenger of reactive oxygen species in vivo? Evidence for its initiation of stress signaling pathways that promote endogenous antioxidant capacity, IUBMB Life, 60, 362, 10.1002/iub.40

Snell, 1937, Growth factors for bacteria. VI: fraction- ation and properties of an accessory factor for lactic acid bacteria, Biochem. J., 31, 1789, 10.1042/bj0311789

Suh, 2004, (R)-alpha-lipoic acid reverses the age-related loss in GSH redox status in post-mitotic tissues: evidence for increased cysteine requirement for GSH synthesis, Arch. Biochem. Biophys., 423, 126, 10.1016/j.abb.2003.12.020

Takaishi, 2007, Transepithelial transport of alpha-lipoic acid across human intestinal Caco-2 cell monolayers, J. Agric. Food Chem., 55, 5253, 10.1021/jf063624i

Thiebaut, 1987, Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues, Proc. Natl. Acad. Sci., 84, 7735, 10.1073/pnas.84.21.7735

Uchida, 2015, Enantioselective pharmacokinetics of α-lipoic acid in rats, Int. J. Mol. Sci., 16, 22781, 10.3390/ijms160922781

Wada, 1997, Why do mitochondria synthesize fatty acids? Evidence for involvement in lipoic acid production, Proc. Proc. Natl. Acad. Sci. USA, 94, 1591, 10.1073/pnas.94.4.1591

Weischer, 2001

Zehnpfennig, 2015, Interaction of α-lipoic acid with the human Na+/multivitamin transporter (hSMVT), J. Biol. Chem., 290, 16372, 10.1074/jbc.M114.622555

Zhao, 2017, Neurochemical effects of the R form of α-lipoic acid and its neuroprotective mechanism in cellular models of Parkinson's disease, Int. J. Biochem. Cell Biol., 87, 86, 10.1016/j.biocel.2017.04.002