Evaluation of testicular degeneration induced by low‐frequency electromagnetic fields

Journal of Applied Toxicology - Tập 32 Số 3 - Trang 210-218 - 2012
Bruno Mendes Tenório1, George Chaves Jimenez1, Rosana Nogueira de Morais2, Christina Alves Peixoto3, Romildo de Albuquerque Nogueira1, Valdemiro Amaro da Silva1,4
1Department of Animal Morphology and Physiology, Federal Rural University of Pernambuco, Recife, Pernambuco, Brazil
2Department of Physiology, Federal University of Paraná, Curitiba, Paraná, Brazil
3Northeast Strategic Technologies Center (INT-CETENE), Recife, Pernambuco, Brazil
4V. A. Silva Junior, Department of Animal Morphology and Physiology, Federal Rural University of Pernambuco, Recife, Pernambuco, Brazil.

Tóm tắt

ABSTRACTThe population exposure to electromagnetic fields (EMF) has been growing in recent decades. The generation, distribution and use of electric energy can generate low‐frequency electromagnetic fields. The present study investigates the effects of EMF (60 Hz and 1 mT) on spermatogenesis of rats during different periods of maturation. Wistar rats were exposed to EMF from day 13 of gestation to postnatal day 21 or 90 in three daily applications of 30 min. Plasma testosterone concentration was not changed by EMF exposure; however, histopathological and histomorphometrical analyses of the testes showed testicular degeneration in a subset of animals exposed to EMF. The magnitude of the degenerative process varied between those individuals affected, indicating different individual sensitivity to EMF. The main alterations observed through transmission electron microscopy were highly electron‐dense mitochondria with loss of their organization and cristae. Exposure to 60 Hz and 1 mT EMF can disturb spermatogenesis and may produce subfertility or infertility. Copyright © 2011 John Wiley & Sons, Ltd.

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Journal of Applied Toxicology

Tập 32 Số 3

210-218

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