Evaluation of a novel real-time PCR assay for the detection, identification and quantification of Plasmodium species causing malaria in humans
Tóm tắt
The entry of PCR-based techniques into malaria diagnostics has improved the sensitivity and specificity of the detection of
The samples used in this study comprised reference samples, patient samples, and synthetic controls. The following analytical performance characteristics of the MC004 assay were determined: analytical specificity, limit of detection, the ability to detect mixed infections, and the potential to determine the level of parasitaemia of
No false positive or false negative results were observed. The limit of detection of
Based upon the analytical performance characteristics that were determined, the MC004 assay showed performance suitable for use in clinical settings, as well as epidemiological studies.
Từ khóa
Tài liệu tham khảo
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