Estrogen induced downregulation of gene expression and cell biological processes critical for genital tubercle formation via DNA methylation

Springer Science and Business Media LLC - Tập 6 - Trang 1-2 - 2013
Jia-Xin Jiang1,2, Karen J Aitken2, Tyler P Kirwan2, Sevan Hopyan1,3, Darius J Bägli1,4,2
1Department of Physiology, University of Toronto, Toronto, Canada
2Research Institute, Department of Developmental &, Stem Cell Biology Hospital for Sick Children, Toronto, Canada
3Division of Orthopaedics, Department of Surgery, Hospital for Sick Children, Toronto, Canada
4Department of Urology, Hospital for Sick Children, Toronto, Canada

Tài liệu tham khảo

Kalfa N, Paris F, Soyer-Gobillard MO, Daures JP, Sultan C: Prevalence of hypospadias in grandsons of women exposed to diethylstilbestrol during pregnancy: a multigenerational national cohort study. Fertil Steril. 2011, 95 (8): 2574-2577. 10.1016/j.fertnstert.2011.02.047. Bromer JG, Wu J, Zhou Y, Taylor HS: Hypermethylation of homeobox A10 by in utero diethylstilbestrol exposure: an epigenetic mechanism for altered developmental programming. Endocrinology. 2009, 150 (7): 3376-3382. 10.1210/en.2009-0071.
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