Tuyến Lympho T Người Đặc Hiệu Virus Epstein-Barr Biểu Hiện Các Thụ Thể Tế Bào T Chimeric Chống U: Tiềm Năng Cải Thiện Điều Trị Miễn Dịch

Eshhar, 1993, Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma or zeta subunits of the immunoglobulin and T-cell receptors., Proc Natl Acad Sci U S A., 90, 720, 10.1073/pnas.90.2.720 Stancovski, 1993, Targeting of T lymphocytes to Neu/HER2-expressing cells using chimeric single chain Fv receptors., J Immunol., 151, 6577, 10.4049/jimmunol.151.11.6577 Altenschmidt, 1997, Adoptive transfer of in vitro-targeted, activated T lymphocytes results in total tumor regression., J Immunol., 159, 5509, 10.4049/jimmunol.159.11.5509 Hwu, 1995, In vivo antitumor activity of T cells redirected with chimeric antibody/T-cell receptor genes., Cancer Res., 55, 3369 McGuinness, 1999, Anti-tumor activity of human T cells expressing the CC49-zeta chimeric immune receptor [see comments]., Hum Gene Ther., 10, 165, 10.1089/10430349950018968 Mitsuyasu, 2000, Prolonged survival and tissue trafficking following adoptive transfer of CD4zeta gene-modified autologous CD4(+) and CD8(+) T cells in human immunodeficiency virus-infected subjects., Blood., 96, 785, 10.1182/blood.V96.3.785 Walker, 2000, Long-term in vivo survival of receptor-modified syngeneic T cells in patients with human immunodeficiency virus infection., Blood., 96, 467 Brocker, 1995, Signals through T cell receptor-zeta chain alone are insufficient to prime resting T lymphocytes., J Exp Med., 181, 1653, 10.1084/jem.181.5.1653 Brocker, 2000, Chimeric Fv-zeta or Fv-epsilon receptors are not sufficient to induce activation or cytokine production in peripheral T cells., Blood., 96, 1999, 10.1182/blood.V96.5.1999 Krause, 1998, Antigen-dependent CD28 signaling selectively enhances survival and proliferation in genetically modified activated human primary T lymphocytes., J Exp Med., 188, 619, 10.1084/jem.188.4.619 Khanna, 2000, Role of cytotoxic T lymphocytes in Epstein-Barr virus-associated diseases [in process citation]., Annu Rev Microbiol., 54, 19, 10.1146/annurev.micro.54.1.19 Heslop, 1996, Long-term restoration of immunity against Epstein-Barr virus infection by adoptive transfer of gene-modified virus-specific T lymphocytes., Nat Med., 2, 551, 10.1038/nm0596-551 Rooney, 1995, Use of gene-modified virus-specific T lymphocytes to control Epstein-Barr-virus-related lymphoproliferation., Lancet., 345, 9, 10.1016/S0140-6736(95)91150-2 Rooney, 1998, Infusion of cytotoxic T cells for the prevention and treatment of Epstein-Barr virus-induced lymphoma in allogeneic transplant recipients., Blood., 92, 1549, 10.1182/blood.V92.5.1549 Roskrow, 1998, Epstein-Barr virus (EBV)-specific cytotoxic T lymphocytes for the treatment of patients with EBV-positive relapsed Hodgkin's disease., Blood., 91, 2925, 10.1182/blood.V91.8.2925.2925_2925_2934 Kinsella, 1996, Episomal vectors rapidly and stably produce high-titer recombinant retrovirus., Hum Gene Ther., 7, 1405, 10.1089/hum.1996.7.12-1405 Mujoo, 1989, Functional properties and effect on growth suppression of human neuroblastoma tumors by isotype switch variants of monoclonal antiganglioside GD2 antibody 14.18., Cancer Res., 49, 2857 Sen, 1997, Preclinical evaluation in nonhuman primates of murine monoclonal anti-idiotype antibody that mimics the disialoganglioside GD2., Clin Cancer Res., 3, 1969 Smith, 1985, Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface., Science., 228, 1315, 10.1126/science.4001944 Weissman, 1988, Molecular cloning and chromosomal localization of the human T-cell receptor zeta chain: distinction from the molecular CD3 complex., Proc Natl Acad Sci U S A., 85, 9709, 10.1073/pnas.85.24.9709 Riviere, 1995, Effects of retroviral vector design on expression of human adenosine deaminase in murine bone marrow transplant recipients engrafted with genetically modified cells., Proc Natl Acad Sci U S A., 92, 6733, 10.1073/pnas.92.15.6733 Schulz, 1984, Detection of ganglioside GD2 in tumor tissues and sera of neuroblastoma patients., Cancer Res., 44, 5914 Gottschalk, 2001, An Epstein-Barr virus deletion mutant associated with fatal lymphoproliferative disease unresponsive to therapy with virus-specific CTLs., Blood., 97, 835, 10.1182/blood.V97.4.835 Walter, 1995, Reconstitution of cellular immunity against cytomegalovirus in recipients of allogeneic bone marrow by transfer of T-cell clones from the donor., N Engl J Med., 333, 1038, 10.1056/NEJM199510193331603 Roberts, 1994, Targeting of human immunodeficiency virus-infected cells by CD8+ T lymphocytes armed with universal T-cell receptors., Blood., 84, 2878, 10.1182/blood.V84.9.2878.2878 Yang, 1997, Lysis of HIV-1-infected cells and inhibition of viral replication by universal receptor T cells., Proc Natl Acad Sci U S A., 94, 11478, 10.1073/pnas.94.21.11478 Brodie, 1999, In vivo migration and function of transferred HIV-1-specific cytotoxic T cells., Nat Med., 5, 34, 10.1038/4716 Cardin, 1996, Progressive loss of CD8+ T cell-mediated control of a gamma-herpesvirus in the absence of CD4+ T cells., J Exp Med., 184, 863, 10.1084/jem.184.3.863 Matloubian, 1994, CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection., J Virol., 68, 8056, 10.1128/JVI.68.12.8056-8063.1994 Evavold, 1991, Separation of IL-4 production from Th cell proliferation by an altered T cell receptor ligand., Science., 252, 1308, 10.1126/science.1833816 Hemmer, 1997, Human T-cell response to myelin basic protein peptide (83-99): extensive heterogeneity in antigen recognition, function, and phenotype., Neurology., 49, 1116, 10.1212/WNL.49.4.1116 Wandinger, 2000, Association between clinical disease activity and Epstein-Barr virus reactivation in MS., Neurology., 55, 178, 10.1212/WNL.55.2.178 Sarid, 2001, Epstein-Barr virus specific salivary antibodies as related to stress caused by examinations., J Med Virol., 64, 149, 10.1002/jmv.1030 Glaser, 1999, The differential impact of training stress and final examination stress on herpesvirus latency at the United States Military Academy at West Point., Brain Behav Immun., 13, 240, 10.1006/brbi.1999.0566 Nash, 1996, FK506 in combination with methotrexate for the prevention of graft-versus-host disease after marrow transplantation from matched unrelated donors., Blood., 88, 3634, 10.1182/blood.V88.9.3634.bloodjournal8893634 Gustafsson, 2000, Epstein-Barr virus (EBV) load in bone marrow transplant recipients at risk to develop posttransplant lymphoproliferative disease: prophylactic infusion of EBV-specific cytotoxic T cells., Blood., 95, 807, 10.1182/blood.V95.3.807.003k24_807_814 Barker, 1991, Effect of a chimeric anti-ganglioside GD2 antibody on cell-mediated lysis of human neuroblastoma cells., Cancer Res., 51, 144 Frost, 1997, A phase I/IB trial of murine monoclonal anti-GD2 antibody 14.G2a plus interleukin-2 in children with refractory neuroblastoma: a report of the Children's Cancer Group., Cancer., 80, 317, 10.1002/(SICI)1097-0142(19970715)80:2<317::AID-CNCR21>3.0.CO;2-W