Epigenetic Modifications to H3K9 in Renal Tubulointerstitial Cells after Unilateral Ureteric Obstruction and TGF-β1 Stimulation

Tim D. Hewitson1,2, Stephen G. Holt1,2, Sven‐Jean Tan2, Belinda Wigg2, Chrishan S. Samuel3, Edward R. Smith1,2
1Department of Medicine, The Royal Melbourne Hospital, The University of Melbourne, Melbourne, VIC, Australia
2Department of Nephrology, The Royal Melbourne Hospital, Melbourne, VIC, Australia
3Cardiovascular Disease Program, Biomedicine Discovery Institute and Department of Pharmacology, Monash University, Melbourne, VIC, Australia

Tóm tắt

Từ khóa


Tài liệu tham khảo

Allis, 2016, The molecular hallmarks of epigenetic control., Nat. Rev. Genet., 17, 487, 10.1038/nrg.2016.59

Andrulis, 1998, Perinuclear localization of chromatin facilitates transcriptional silencing., Nature, 394, 592, 10.1038/29100

Bannister, 2001, Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain., Nature, 410, 120, 10.1038/35065138

Barski, 2007, High-resolution profiling of histone methylations in the human genome., Cell, 129, 823, 10.1016/j.cell.2007.05.009

Bechtel, 2010, Methylation determines fibroblast activation and fibrogenesis in the kidney., Nat. Med., 16, 544, 10.1038/nm.2135

Border, 1990, Transforming growth factor-beta 1 induces extracellular matrix formation in glomerulonephritis., Cell Differ. Dev., 32, 425, 10.1016/0922-3371(90)90059-6

Chevalier, 1996, Growth factors and apoptosis in neonatal ureteral obstruction., J. Am. Soc. Nephrol., 7, 1098, 10.1681/ASN.V781098

Chevalier, 2009, Ureteral obstruction as a model of renal interstitial fibrosis and obstructive nephropathy., Kidney Int., 75, 1145, 10.1038/ki.2009.86

Cho, 2012, Epigenetic regulation of myofibroblast differentiation and extracellular matrix production in nasal polyp-derived fibroblasts., Clin. Exp. Allergy, 42, 872, 10.1111/j.1365-2222.2011.03931.x

Darby, 1990, Alpha-smooth muscle actin is transiently expressed by myofibroblasts during experimental wound healing., Lab. Invest., 63, 21

Doi, 2011, Klotho inhibits transforming growth factor-beta1 (TGF-beta1) signaling and suppresses renal fibrosis and cancer metastasis in mice., J. Biol. Chem., 286, 8655, 10.1074/jbc.M110.174037

Drygin, 2010, The RNA polymerase I transcription machinery: an emerging target for the treatment of cancer., Ann. Rev. Pharmacol. Toxicol., 50, 131, 10.1146/annurev.pharmtox.010909.105844

Franke, 1979, Widespread occurrence of intermediate-sized filaments of the vimentin-type in cultured cells from diverse vertebrates., Exp. Cell Res., 123, 25, 10.1016/0014-4827(79)90418-X

Ghamari, 2013, In vivo live imaging of RNA polymerase II transcription factories in primary cells., Genes Dev., 27, 767, 10.1101/gad.216200.113

Gomez, 2016, MicroRNAs as novel therapeutic targets to treat kidney injury and fibrosis., Am. J. Physiol. Renal Physiol., 310, F931, 10.1152/ajprenal.00523.2015

Greer, 2012, Histone methylation: a dynamic mark in health, disease and inheritance., Nat. Rev. Genet., 13, 343, 10.1038/nrg3173

Grimwood, 2009, Propagation and culture of renal fibroblasts., Methods Mol. Biol., 466, 25, 10.1007/978-1-59745-352-3_3

Guo, 2009, Abrogation of TGF-beta1-induced fibroblast-myofibroblast differentiation by histone deacetylase inhibition., Am. J. Physiol. Lung Physiol., 297, L864, 10.1152/ajplung.00128.2009

Hewitson, 2009, Renal tubulointerstitial fibrosis: common but never simple., Am. J. Physiol. Renal Physiol., 296, F1239, 10.1152/ajprenal.90521.2008

Hewitson, 2016, Estrogens do not protect, but androgens exacerbate, collagen accumulation in the female mouse kidney after ureteric obstruction., Life Sci., 158, 130, 10.1016/j.lfs.2016.06.022

Hewitson, 2010, Antifibrotic properties of relaxin: in vivo mechanism of action in experimental renal tubulointerstitial fibrosis., Endocrinology, 151, 4938, 10.1210/en.2010-0286

Irifuku, 2016, Inhibition of H3K9 histone methyltransferase G9a attenuates renal fibrosis and retains klotho expression., Kidney Int., 89, 147, 10.1038/ki.2015.291

Koch, 2007, The landscape of histone modifications across 1% of the human genome in five human cell lines., Genome Res., 17, 691, 10.1101/gr.5704207

Loghman-Adham, 2003, Immortalized epithelial cells from human autosomal dominant polycystic kidney cysts., Am. J. Physiol. Renal Physiol., 285, F397, 10.1152/ajprenal.00310.2002

Mann, 2010, MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis., Gastroenterology, 138, e1, 10.1053/j.gastro.2009.10.002

Marumo, 2010, Histone deacetylase modulates the proinflammatory and -fibrotic changes in tubulointerstitial injury., Am. J. Physiol. Renal Physiol., 298, F133, 10.1152/ajprenal.00400.2009

McClelland, 2015, miR-21 promotes renal fibrosis in diabetic nephropathy by targeting PTEN and SMAD7., Clin. Sci., 129, 1237, 10.1042/cs20150427

Meng, 2016, TGF-beta: the master regulator of fibrosis., Nat. Rev. Nephrol., 12, 325, 10.1038/nrneph.2016.48

Obier, 2010, Chromatin flow cytometry identifies changes in epigenetic cell states., Cells Tissues Organs, 191, 167, 10.1159/000240247

Perugorria, 2012, Histone methyltransferase ASH1 orchestrates fibrogenic gene transcription during myofibroblast transdifferentiation., Hepatology, 56, 1129, 10.1002/hep.25754

Reddy, 2011, Epigenetics in diabetic kidney disease., J. Am. Soc. Nephrol., 22, 2182, 10.1681/ASN.2011060629

Reddy, 2015, Recent developments in epigenetics of acute and chronic kidney diseases., Kidney Int., 88, 250, 10.1038/ki.2015.148

Sasaki, 2016, Inhibition of SET domain-containing lysine methyltransferase 7/9 ameliorates renal fibrosis., J. Am. Soc. Nephrol., 27, 203, 10.1681/asn.2014090850

Schindelin, 2012, Fiji: an open-source platform for biological-image analysis., Nat. Methods, 9, 676, 10.1038/nmeth.2019

Smith, 2017, FGF23 is synthesised locally by renal tubules and activates injury-primed fibroblasts., Sci. Rep., 10.1038/s41598-017-02709-w

Sun, 2010, Epigenetic histone methylation modulates fibrotic gene expression., J. Am. Soc. Nephrol., 21, 2069, 10.1681/ASN.2010060633

Taverna, 2007, How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers., Nat. Struct. Mol. Biol., 14, 1025, 10.1038/nsmb1338

Towbin, 2013, Mechanisms of heterochromatin subnuclear localization., Trends Biochem. Sci., 38, 356, 10.1016/j.tibs.2013.04.004

Wing, 2013, Epigenetics of progression of chronic kidney disease: fact or fantasy?, Semin. Nephrol., 33, 363, 10.1016/j.semnephrol.2013.05.008

Yu, 2015, Analysis of histone modifications at human ribosomal DNA in liver cancer cell., Sci. Rep., 5, 10.1038/srep18100

Yuan, 2013, Involvement of p300/CBP and epigenetic histone acetylation in TGF-beta1-mediated gene transcription in mesangial cells., Am. J. Physiol. Renal Physiol., 304, F601, 10.1152/ajprenal.00523.2012

Zhou, 2010, TGFbeta mediated transition of corneal fibroblasts from a proinflammatory state to a profibrotic state through modulation of histone acetylation., J. Cell. Physiol., 224, 135, 10.1002/jcp.22110