Epidemiology of vertebral osteomyelitis (VO) in France: analysis of hospital-discharge data 2002–2003

Epidemiology and Infection - Tập 136 Số 5 - Trang 653-660 - 2008
L Guillon Grammatico1, S. Baron1, Emmanuel Rüsch1,2, Benoît Lepage3, Nathalie Surer4, J C Desenclos5, Jean Marc Besnier6,2
1CHRU de Tours, Service d'Information Médicale et Economie de la Santé, Tours, France
2Université François RabelaisTours, France
3CHU de Poitiers, Service d'Information Médicale, Poitiers, France
4CHU de Nantes, Service d'Information Médicale et Economie de la Santé, Nantes, France
5Institut National de Veille Sanitaire, Paris, France
6CHRU de Tours, Service de Médecine Interne et Maladies Infectieuses, Tours, France

Tóm tắt

SUMMARY

Vertebral osteomyelitis (VO) is a rare event. To estimate the incidence of VO in France for 2002–2003, national hospital-discharge data were used. Hospital stays were categorized as definite, probable or possible VO. Unique patient identification numbers allowed the investigators to link patients with multiple hospital stays and to analyse data for individual patients. A sample of medical records was reviewed to assess the specificity of the VO case definition. In 2002–2003, 1977 and 2036 hospital stays corresponding to 1422 and 1425 patients (median age 59 years, male:female ratio 1·5) were classified as definite (64%), probable (24%) and possible (12%) VO. The overall incidence of VO was 2·4/100 000. Incidence increased with age: 0·3/100 000 (<20 years), 3·5/100 000 (50–70 years) and 6·5/100 000 (>70 years). The main infectious agents reported wereStaphylococcusspp. (38%) andMycobacterium tuberculosis(31%). The most frequent comorbidities were septicaemia (27%) and endocarditis (9%). Three percent of patients died. A review of 90 medical records confirmed the diagnosis of VO in 94% of cases. Using a hospital database and a specific case definition, nationwide surveillance of VO is possible.

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Epidemiology and Infection

Tập 136 Số 5

653-660

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