Enzymatic Inhibitors from Natural Sources: A Huge Collection of New Potential Drugs

Nguyen, P.H., Tuan, H.N., Hoang, D.T., Vu, Q.T., Pham, M.Q., Tran, M.H., and To, D.C. (2019). Glucose Uptake Stimulatory and PTP1B Inhibitory Activities of Pimarane Diterpenes from Orthosiphon stamineus Benth. Biomolecules, 9.

Alqahtani, A.S., Hidayathulla, S., Rehman, M.T., ElGamal, A.A., Al-Massarani, S., Razmovski-Naumovski, V., Alqahtani, M.S., El Dib, R.A., and AlAjmi, M.F. (2019). Alpha-Amylase and Alpha-Glucosidase Enzyme Inhibition and Antioxidant Potential of 3-Oxolupenal and Katononic Acid Isolated from Nuxia oppositifolia. Biomolecules, 10.

Ur Rehman, N., Halim, S.A., Al-Azri, M., Khan, M., Khan, A., Rafiq, K., Al-Rawahi, A., Csuk, R., and Al-Harrasi, A. (2020). Triterpenic Acids as Non-Competitive α-Glucosidase Inhibitors from Boswellia elongata with Structure-Activity Relationship: In Vitro and In Silico Studies. Biomolecules, 10.

Dudoit, A., Benbouguerra, N., Richard, T., Hornedo-Ortega, R., Valls-Fonayet, J., Coussot, G., and Saucier, C. (2020). α-Glucosidase Inhibitory Activity of Tannat Grape Phenolic Extracts in Relation to Their Ripening Stages. Biomolecules, 10.

Kalhotra, P., Chittepu, V.C.S.R., Osorio-Revilla, G., and Gallardo-Velazquez, T. (2020). Phytochemicals in Garlic Extract Inhibit Therapeutic Enzyme DPP-4 and Induce Skeletal Muscle Cell Proliferation: A Possible Mechanism of Action to Benefit the Treatment of Diabetes Mellitus. Biomolecules, 10.

Balestri, F., Poli, G., Pineschi, C., Moschini, R., Cappiello, M., Mura, U., Tuccinardi, T., and Del Corso, A. (2020). Aldose Reductase Differential Inhibitors in Green Tea. Biomolecules, 10.

Sadeer, N.B., Sinan, K.I., Cziáky, Z., Jekő, J., Zengin, G., Jeewon, R., Abdallah, H.H., Rengasamy, K.R.R., and Mahomoodally, M.F. (2020). Assessment of the Pharmacological Properties and Phytochemical Profile of Bruguiera gymnorhiza (L.) Lam Using in Vitro Studies, in Silico Docking, and Multivariate Analysis. Biomolecules, 10.

Badeggi, U.M., Ismail, E., Adeloye, A.O., Botha, S., Badmus, J.A., Marnewick, J.L., Cupido, C.N., and Hussein, A.A. (2020). Green Synthesis of Gold Nanoparticles Capped with Procyanidins from Leucosidea sericea as Potential Antidiabetic and Antioxidant Agents. Biomolecules, 10.

Marin, V., Iturra, A., Opazo, A., Schmidt, B., Heydenreich, M., Ortiz, L., Jiménez, V.A., and Paz, C. (2020). Oxidation of Isodrimeninol with PCC Yields Drimane Derivatives with Activity against Candida Yeast by Inhibition of Lanosterol 14-Alpha Demethylase. Biomolecules, 10.

Coy-Barrera, E. (2020). Discrimination of Naturally-Occurring 2-Arylbenzofurans as Cyclooxygenase-2 Inhibitors: Insights into the Binding Mode and Enzymatic Inhibitory Activity. Biomolecules, 10.

Ly, T.D., Kleine, A., Fischer, B., Schmidt, V., Hendig, D., Kuhn, J., Knabbe, C., and Faust, I. (2020). Identification of Putative Non-Substrate-Based XT-I Inhibitors by Natural Product Library Screening. Biomolecules, 10.

Zazeri, G., Povinelli, A.P.R., de Freitas Lima, M., and Cornélio, M.L. (2020). The Cytokine IL-1β and Piperine Complex Surveyed by Experimental and Computational Molecular Biophysics. Biomolecules, 10.

Shahin-Kaleybar, B., Niazi, A., Afsharifar, A., Nematzadeh, G., Yousefi, R., Retzl, B., Hellinger, R., Muratspahić, E., and Gruber, C.W. (2020). Isolation of Cysteine-Rich Peptides from Citrullus colocynthis. Biomolecules, 10.

Chen, X., Chen, D., Huang, L., Chen, X., Zhou, M., Xi, X., Ma, C., Chen, T., and Wang, L. (2020). Identification and Target-Modification of SL-BBI: A Novel Bowman-Birk Type Trypsin Inhibitor from Sylvirana latouchii. Biomolecules, 10.

Baier, A., and Szyszka, R. (2020). Compounds from Natural Sources as Protein Kinase Inhibitors. Biomolecules, 10.

Tisi, R., Gaponenko, V., Vanoni, M., and Sacco, E. (2020). Natural Products Attenuating Biosynthesis, Processing, and Activity of Ras Oncoproteins: State of the Art and Future Perspectives. Biomolecules, 10.