Masaki Ohwa1, Ernest L. Eliel1
1Department of Chemistry, University of North Carolina
Tóm tắt
Abstract
(+)- and (−)-Frontalin have been obtained from a chiral 1,3-oxathiane precursor in a short (3-step) synthesis in moderate (70%) enantiomeric excess (e.e.). A longer (6-step) modification gives the two enantiomers in 96% e.e. Overall yields range from 28 to 43%.
