Electrical properties of isolated demyelinated rat nerve fibres

Wiley - Tập 113 Số 2 - Trang 161-166 - 1981
Tom Brismar1
1Department of Clinical Neurophysiology. Karolinska sjukhuset, S-10401 Stockholm, Sweden

Tóm tắt

Isolated large rat nerve fibres with diphtheria toxin induced paranodal demyelination were investigated. These fibres had increased membrane time constant of the demyelinated nodal segment, related to a large increase in capacitance (5 to 50 times). The resting conductance was less increased (2 to 3 times), meaning that the internodal axolemma has considerably higher resting resistance than the nodal membrane. A large variation in action potential amplitude was found which was unrelated to the size of the nodal widening and the passive electrical properties.

Từ khóa


Tài liệu tham khảo

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Wiley

Tập 113 Số 2

161-166

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