Effects of intravoxel incoherent motions (IVIM) in steady‐state free precession (SSFP) imaging: application to molecular diffusion imaging

Magnetic Resonance in Medicine - Tập 10 Số 3 - Trang 324-337 - 1989
Denis Le Bihan1, Robert Turner2, James R. MacFall3
1Diagnostic Radiology Department, The Warren Grant Magnuson Clinical Center, Building 10, Room IC660,
2Bioengineering and Instrumentation Branch, National Institutes of Health, Bethesda, Maryland 20892
3General Electric Company, Medical Systems Group, P.O. Box 414, Milwaukee, Wisconsin 53201

Tóm tắt

AbstractA theoretical analysis of the effects of diffusion and perfusion in steady‐state free precession (SSFP) imaging sequences sensitized to intravoxel incoherent motions by magnetic field gradients is presented and supported by phantom studies. The capability of such sequences to image diffusion and perfusion quickly was recently demonstrated. The possible residual effects of T1 and T2 in diffusion measurements are evaluated, as are the effects of the sequence design and the acquisition parameters (repetition time, flip angle, gradient pulses). It is shown theoretically and confirmed by experiments on phantoms that diffusion coefficients can be directly measured from SSFP images when large enough diffusion gradient pulses are used. © 1989 Academic Press, Inc.

Từ khóa


Tài liệu tham khảo

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Thông tin
Thông tin xuất bản

Magnetic Resonance in Medicine

Tập 10 Số 3

324-337

Thông tin tác giả