Effects of gastrocystoplasty on serum gastrin levels and gastric acid secretion

British Journal of Surgery - Tập 70 Số 5 - Trang 275-277 - 1983
S. T. K. Lim1, Shiu‐Kum Lam1, N. W. Lee1, J Wong1, Ghim Ping Ong1
1Departments of Surgery and Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong

Tóm tắt

Abstract Hypersecretion of gastric acid and hypergastrinaemia occur when the antrum of the stomach is transposed as a diverticulum to the colon. Thus, when an antral pouch is transposed to increase bladder capacity or to replace the bladder as a gastrocystoplasty, similar pathophysiological disturbances can be anticipated. However, previous studies in our laboratories in dogs have shown that acid overproduction and stomal ulcerations do not occur. This paper reports the results of gastrocystoplasty in 13 patients followed up from 1 to 6 years. Gastric acid hypersecretion and hypergastrinaemia did not occur.

Từ khóa


Tài liệu tham khảo

Dragstedt, 1951, Experimental hyperfunction of the gastric antrum with ulcer formation, Ann. Surg., 134, 332, 10.1097/00000658-195109000-00004

Friesen, 1974, An experimental study of the antral gastrin mechanism, Surgery, 75, 517

Korman, 1972, Hypergastrinaemia due to an excluded gastric antrum: a proposed method for differentiation from the Zollinger–Ellison syndrome, Aust. NZ J. Med., 2, 266, 10.1111/j.1445-5994.1972.tb03073.x

Leong, 1972, Gastrocystoplasty in dogs, Aust. NZ J. Surg., 41, 272, 10.1111/j.1445-2197.1969.tb06307.x

Lam, 1976, Inhibition of sulpiride on the cephalic phase of gastric acid and gastrin secretion in duodenal ulcer patients, Scand. J. Gastroenterol., 11, 27, 10.1080/00365521.1976.12097069

Baron, 1973, The clinical application of gastric secretion measurements, Clin. Gastroenterol., 2, 293, 10.1016/S0300-5089(21)00031-6

Lam, 1980, Comparison of maximal acid output and gastrin response to meals in Chinese and Scottish normal and duodenal ulcer subjects, Gut, 21, 324, 10.1136/gut.21.4.324

Leong, 1978, Use of the stomach for bladder replacement and urinary diversion, Ann. R. Coll. Surg. Engl., 60, 283

Schiller, 1980, Distention-induced gastrin release. Effects of luminal acidification and intravenous atropine, Gastroenterology, 78, 912, 10.1016/0016-5085(80)90771-4

Walsh, 1980, Physiology and pathology of gastrin, Clin. Gastroenterol., 9, 567, 10.1016/S0300-5089(21)00472-7

Bedi, 1969, Effect of bilesalts on antral gastrin release, Br. J. Surg., 56, 695

Thông tin
Thông tin xuất bản

British Journal of Surgery

Tập 70 Số 5

275-277

Thông tin tác giả