Effects of Chlorhexidine and Fluoride on Irradiated Enamel and Dentin

SAGE Publications - Tập 90 Số 5 - Trang 659-664 - 2011
Carlos José Soares1, N.A. Neiva1, Priscilla Barbosa Ferreira Soares1, Paula Dechichi2, Veridiana Resende Novais1, Lucas Zago Naves3, Marcelo Rocha Marques4
1Biomechanics Group, School of Dentistry, Federal University of Uberlândia, Dept. of Operative Dentistry and Dental Materials, Av. Pará 1720, Bloco 2B, Sala 2B-24, Campus Umuarama, Uberlândia, MG 38400-902, Brazil
2Histology Department, Federal University of Uberlândia
3Department of Restorative Dentistry, Dental Materials Division, Piracicaba Dental School, University of Campinas, Piracicaba, SP, Brazil
4Department of Morphology, Division of Histology, Piracicaba Dental School, University of Campinas, Piracicaba, SP, Brazil

Tóm tắt

The effectiveness of mouthwash protocols in preventing gamma irradiation therapy damage to the ultimate tensile strength (UTS) of enamel and dentin is unknown. It was hypothesized that the use of chlorhexidine and fluoride mouthwash would maintain the UTS of dental structures. One hundred and twenty teeth were divided into 2 groups: irradiated (subjected to 60 Gy of gamma irradiation in daily increments of 2 Gy) and non-irradiated. They were then subdivided into 2 mouthwash protocols used 3 times per day: 0.12% chlorhexidine, 0.05% sodium fluoride, and control group (n = 10). The specimens were evaluated by microtensile testing. The results of the Tukey test ( p < 0.05) indicated that the gamma irradiation therapy significantly reduced the UTS of the enamel, crown, and root dentin. Macromolecular alterations were suggested by optical retardation data in dentin. Structural alterations, in both substrates, were detected by scanning electron microscopy analysis. Mouthwash with 0.12% chlorhexidine partially prevented the damage to the mechanical properties of the irradiated crown dentin, whereas the 0.05% sodium-fluoride-irradiated enamel showed UTS similar to that of non-irradiated enamel.

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SAGE Publications

Tập 90 Số 5

659-664

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