Effectiveness of cryotherapy treatment for cervical intraepithelial neoplasia

International Journal of Gynecology & Obstetrics - Tập 101 - Trang 172-177 - 2008
Silvana Luciani1, Miguel Gonzales2, Sergio Munoz3, Jose Jeronimo4, Sylvia Robles5
1Unit of Non-Communicable Diseases, Pan American Health Organization, Washington, DC, USA
2Health Surveillance and Disease Management, Pan American Health Organization - Representation in Peru, Lima, Peru
3Clinical Epidemiology Research and Training Center, University of La Frontera, Temuco, Chile
4Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
5Human Development Network, World Bank, Washington DC, USA

Tóm tắt

AbstractObjectiveTo assess the effectiveness of cryotherapy treatment delivered by general practitioners in primary care settings, as part of a screen‐and‐treat approach for cervical cancer prevention.MethodWomen aged between 25 and 49 years residing in San Martin, Peru, who were positive on visual inspection screening were treated, if eligible, with cryotherapy following biopsy. At 12 months post cryotherapy treatment the participants were evaluated for treatment effectiveness and examined by visual inspection and Papanicolaou test and, if positive, referred to a gynecologist for colposcopy and biopsy.ResultsCryotherapy treatment was performed for 1398 women; of these, 531 (38%) had a histology result of cervical intraepithelial neoplasia (CIN). Cryotherapy effectively cured CIN in 418 (88%) women, including 49 (70%) women with a baseline diagnosis of CIN 3.ConclusionCryotherapy is an effective treatment for cervical precancerous lesions; it can easily be administered by general practitioners in primary care settings following visual inspection screening.

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International Journal of Gynecology & Obstetrics

Tập 101

172-177

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