Effectiveness of Ultrasound-Guided Radiofrequency Ablation in the Treatment of 36 Renal Cell Carcinoma Tumours Compared with Published Results of Using Computed Tomography Guidance

Canadian Association of Radiologists Journal - Tập 63 - Trang S23-S32 - 2012
Kellie Davis1, Ania Kielar2, Katayoun Jafari2
1Department of Radiology, Faculty of Medicine, University of Ottawa, Calgary, Alberta, Canada
2Department of Radiology, The Ottawa Hospital, Civic Campus, Ottawa, Ontario, Canada

Tóm tắt

This study aimed to analyse the outcomes of ultrasound (US) guided radiofrequency ablation (RFA) in patients with renal lesions and to compare our outcomes with published results of ablations carried out when using computed tomography (CT) guidance. This retrospective study evaluated RFA of 36 renal tumours in 32 patients (M = 21, F = 11). The mean patient age was 70 years (range, 39–89 years). Ablations were performed by using either multi-tined applicators or cooled and/or cluster applicators under US guidance. Applicator size varied from 2–5 cm, depending on the size of the index tumour. Conscious sedation was administered by an anesthetist. Follow-up imaging by using contrast-enhanced CT was performed 1, 3, 6, and 12 months after RFA, and yearly thereafter. The mean tumour follow-up time was 12 months (range, 1–35 months). The mean tumour size was 2.7 cm (range, 1–5 cm). Primary effectiveness was achieved in 31 cases (86.1%), with patients in 5 cases (11.1%) demonstrating residual disease. Three patients had repeated sessions, which were technically successful. The remaining 2 patients were not re-treated because of patient comorbidities. As a result, secondary effectiveness was achieved in 34 patients (94.4%). In 1 patient, a new lesion developed in the same kidney but remote from the 2 prior areas of treatment. Hydrodissection was performed in 3 patients (8.3%), manipulation or electrode repositioning in 11 patients (30.6%), and ureteric cooling in 1 patient (2.8%). Minor and major complications occurred in 3 (8.3%) and 3 (8.3%) patients, respectively. Correlation coefficients were calculated for distance from skin to tumour and risk of complication as well as compared with primary and secondary effectiveness. This study demonstrates that US-guided RFA is an effective treatment for renal lesions, with rates of effectiveness and complication rates comparable with published CT-guided RFA results.

Tài liệu tham khảo

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Canadian Association of Radiologists Journal

Tập 63

S23-S32

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