Effect of repeated administration of TRK-820, a κ-opioid receptor agonist, on tolerance to its antinociceptive and sedative actions

Badillo-Martinez, 1984, Monosodium glutamate and analgesia induced by morphine, test-specific effects, Neuropharmacology, 23, 1141, 10.1016/0028-3908(84)90231-4 Bhargava, 1994, Diversity of agents that modify opioid tolerance, physical dependence, abstinence syndrome, and self-administrative behavior, Pharmacol. Rev., 46, 293 Bhargava, 1997, Effect of chronic administration of morphine, U-50,488H and [d-Pen2,d-Pen5]enkephalin on the concentration of cGMP in brain regions and spinal cord of the mouse, Peptides, 18, 1629, 10.1016/S0196-9781(97)00233-7 Bhargava, 1989, Effect of morphine in rats treated chronically with U-50,488H, a κ opioid receptor agonist, Eur. J. Pharmacol., 162, 257, 10.1016/0014-2999(89)90288-4 Bhargava, 1994, Effect of dizocilpine (MK-801) on analgesia and tolerance induced by U-50,488H, a κ-opioid receptor agonist, in the mouse, Brain Res., 649, 111, 10.1016/0006-8993(94)91053-7 Bhargava, 1989, Effect of chronic administration of U-50,488H, on tolerance to its pharmacological actions and multiple opioid receptors in rat brain regions and spinal cord, J. Pharmacol. Exp. Ther., 251, 21 Bradford, 1976, A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding, Anal. Biochem., 72, 248, 10.1016/0003-2697(76)90527-3 Costello, 1988, A novel series of potent and selective agonists at the opioid κ-receptor, Eur. J. Pharmacol., 151, 475, 10.1016/0014-2999(88)90546-8 Cowan, 1990, Effect of nor-binaltorphimine on the behavior of mice and rats receiving multiple injections of U-50,488, Prog. Clin. Biol. Res., 328, 303 Di Chiara, 1988, Opposite effects of μ and κ opiate agonists on dopamine release in the nucleus accumbens and in the dorsal caudate of freely moving rats, J. Pharmacol. Exp. Ther., 244, 1067 Endoh, 1999, Potent antinociceptive effects of TRK-820, a novel κ-opioid receptor agonist, Life Sci., 65, 1685, 10.1016/S0024-3205(99)00417-8 Endoh, 2000, Characterization of the antinociceptive effects of TRK-820 in the rat, Eur. J. Pharmacol., 387, 133, 10.1016/S0014-2999(99)00815-8 Endoh, 2001, TRK-820, a selective κ-opioid agonist, produces potent antinociception in cynomolgus monkeys, Jpn. J. Pharmacol., 85, 282, 10.1254/jjp.85.282 Feng, 1994, Enhancement of the rate of GTP hydrolysis in rat brain by repeated κ-opioid treatment, Brain Res., 667, 133, 10.1016/0006-8993(94)91724-8 Fernandes, 1977, The development of tolerance to morphine in the rat, Psychopharmacology (Berl.), 54, 197, 10.1007/BF00426780 Finney, 1964 Fujibayashi, 1994, Pharmacological properties of R-84760, a novel κ-opioid receptor agonist, Eur. J. Pharmacol., 261, 133, 10.1016/0014-2999(94)90311-5 He, 2002, Regulation of opioid receptor trafficking and morphine tolerance by receptor oligomerization, Cell, 108, 271, 10.1016/S0092-8674(02)00613-X Ho, 1989, Serotonergic involvement in the antinociceptive action of and the development of tolerance to the kappa-opioid receptor agonist, U-50,488H, J. Pharmacol. Exp. Ther., 250, 508 Jiang, 1995, Preventing morphine antinociceptive tolerance by irreversible mu opioid antagonists before the onset of their antagonism, J. Pharmacol. Exp. Ther., 273, 680 Kest, 2001, Morphine tolerance after chronic intracerebroventricular injection in male and female mice, Brain Res., 892, 208, 10.1016/S0006-8993(00)03301-1 Kest, 2000, A comparison of morphine analgesic tolerance in male and female mice, Brain Res., 879, 17, 10.1016/S0006-8993(00)02685-8 Kunihara, 1989, Analgesic activity of spiradoline mesylate (U-62,066E), a κ opioid agonist in mice, Life Sci., 45, 1191, 10.1016/0024-3205(89)90508-0 Li, 1999, U50,488H-induced internalization of the human κ opioid receptor involves a beta-arrestin- and dynamin-dependent mechanism. κ Receptor internalization is not required for mitogen-activated protein kinase activation, J. Biol. Chem., 274, 12087, 10.1074/jbc.274.17.12087 Li, 2000, Mechanisms of agonist-induced down-regulation of the human κ-opioid receptor: internalization is required for down-regulation, Mol. Pharmacol., 58, 795, 10.1124/mol.58.4.795 Li, 2003, Differential regulation of the human κ opioid receptor by agonists: etorphine and levorphanol reduced dynorphin A- and U50,488H-induced internalization and phosphorylation, J. Pharmacol. Exp. Ther., 305, 531, 10.1124/jpet.102.045559 Ling, 1989, Differential development of acute tolerance to analgesia, respiratory depression, gastrointestinal transit and hormone release in a morphine infusion model, Life Sci., 45, 1627, 10.1016/0024-3205(89)90272-5 Loh, 1990, Molecular characterization of opioid receptors, Annu. Rev. Pharmacol. Toxicol., 30, 123, 10.1146/annurev.pa.30.040190.001011 Martin, 1983, Pharmacology of opioids, Pharmacol. Rev., 35, 283 Millan, 1990, κ-Opioid receptors and analgesia, Trends Pharmacol. Sci., 11, 70, 10.1016/0165-6147(90)90321-X Misslin, 1988, Interaction of RO 15-4513 and ethanol on the behaviour of mice: antagonistic or additive effects?, Psychopharmacology (Berl.), 94, 392, 10.1007/BF00174695 Mucha, 1979, Quantitative relationships among measures of morphine tolerance and physical dependence in the rat, Pharmacol. Biochem. Behav., 10, 397, 10.1016/0091-3057(79)90204-1 Nagase, 1998, Discovery of a structurally novel opioid κ-agonist derived from 4,5-epoxymorphinan, Chem. Pharm. Bull. (Tokyo), 46, 366, 10.1248/cpb.46.366 Narita, 1994, Influence of chronic morphine treatment on protein kinase C activity: comparison with butorphanol and implication for opioid tolerance, Brain Res., 650, 175, 10.1016/0006-8993(94)90224-0 Nestler, 1993, Cellular responses to chronic treatment with drugs of abuse, Crit. Rev. Neurobiol., 7, 23 Patel, 2002, Opioid agonists differentially regulate μ-opioid receptors and trafficking proteins in vivo, Mol. Pharmacol., 62, 1464, 10.1124/mol.62.6.1464 Piercey, 1982, U-50488H, a pure kappa receptor agonist with spinal analgesic loci in the mouse, Life Sci., 31, 1197, 10.1016/0024-3205(82)90341-1 Seki, 1999, Pharmacological properties of TRK-820 on cloned μ-, δ- and κ-opioid receptors and nociceptin receptor, Eur. J. Pharmacol., 376, 159, 10.1016/S0014-2999(99)00369-6 Smart, 1996, The stimulatory effects of opioids and their possible role in the development of tolerance, Trends Pharmacol. Sci., 17, 264, 10.1016/0165-6147(96)10023-7 Stafford, 2001, μ-Opioid receptor downregulation contributes to opioid tolerance in vivo, Pharmacol. Biochem. Behav., 69, 233, 10.1016/S0091-3057(01)00525-1 Thorat, 1993, Evidence for the role of nitric oxide in κ opiate tolerance in mice, Brain Res., 621, 171, 10.1016/0006-8993(93)90316-F Togashi, 2002, Antipruritic activity of the κ-opioid receptor agonist, TRK-820, Eur. J. Pharmacol., 435, 259, 10.1016/S0014-2999(01)01588-6 Tsuji, 2000, The novel κ-opioid receptor agonist TRK-820 has no affect on the development of antinociceptive tolerance to morphine in mice, Eur. J. Pharmacol., 394, 91, 10.1016/S0014-2999(00)00139-4 Tsuji, 2001, The novel κ-opioid receptor agonist TRK-820 suppresses the rewarding and locomotor-enhancing effects of morphine in mice, Life Sci., 68, 1717, 10.1016/S0024-3205(01)00957-2 VonVoigtlander, 1983, U-50,488H: a selective and structurally novel non-mu-kappa opioid agonist, J. Pharmacol. Exp. Ther., 224, 7 Xia, 1992, Chronic morphine treatment increases the number, but decreases the affinity of [3H]-U69,593 binding sites in the rat heart, Life Sci., 50, 1143, 10.1016/0024-3205(92)90456-Y Yu, 1997, The development of morphine tolerance and dependence in rats with chronic pain, Brain Res., 756, 141, 10.1016/S0006-8993(97)00132-7