Động lực học số lượng tiểu cầu sớm có giá trị tiên đoán trong hội chứng loạn sản tủy ít nguy cơ

Blood Advances - Tập 2 - Trang 2079-2089 - 2018
Raphael Itzykson1, Simon Crouch2, Erica Travaglino3, Alex Smith2, Argiris Symeonidis4, Eva Hellström-Lindberg5, Guillermo Sanz6,7, Jaroslav Čermák8, Reinhard Stauder9, Chiara Elena3, Ulrich Germing10, Moshe Mittelman11, Saskia Langemeijer12, Krzysztof Mądry13, Aurelia Tatic14, Mette Skov Holm15, Antonio Medina Almeida16, Aleksandar Savic17, Njetočka Gredelj Šimec18, Elisa Luño19
1Département d'Hématologie, Hôpital Saint-Louis, Assistance Publique des Hôpitaux de Paris and Université Paris Diderot, Paris, France;
2Epidemiology and Cancer Statistics Group, Department of Health Sciences, University of York, York, United Kingdom
3Department of Hematology Oncology, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy
4Division Hematology, Department of Internal Medicine, University of Patras Medical School, Patras, Greece
5Division Hematology, Department of Medicine, Karolinska Institute, Stockholm, Sweden;
6Department of Hematology, Hospital Universitario y Politécnico La Fe, Valencia, Spain
7Centro de Investigación Biomédica en Red Cáncer, Instituto Carlos III, Madrid, Spain;
8Department of Clinical Hematology, Institute of Hematology and Blood Transfusion, Praha, Czech Republic;
9Department of Internal Medicine V (Haematology and Oncology), Innsbruck Medical University, Innsbruck, Austria;
10Department of Haematology, Oncology and Clinical Immunology, Universitätsklinik Düsseldorf, Düsseldorf, Germany
11Department of Medicine A, Tel Aviv Sourasky (Ichilov) Medical Center, Sackler Medical Faculty, Tel Aviv University, Tel Aviv, Israel;
12Department of Hematology, Radboud university medical center, Nijmegen, the Netherlands
13Department of Haematology, Oncology and Internal Medicine, Warsaw Medical University, Warsaw, Poland
14Center of Hematology and Bone Marrow Transplantation, Fundeni Clinical Institute, Bucharest, Romania
15Department of Haematology, Aarhus University Hospital, Aarhus, Denmark;
16Department of Hematology, Hospital da Luz, Lisbon, Portugal
17Clinic of Hematology–Clinical Center of Vojvodina, Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia;
18Division of Hematology, Department of Internal Medicine, Merkur University Hospital, Zagreb, Croatia;
19Servicio d'Hematología. Hospital Universitario Central de Asturias, Oviedo, Spain;

Tóm tắt

Các điểm chính Sự giảm số lượng tiểu cầu >25% so với mức cơ sở sau 6 tháng từ chẩn đoán dự đoán kết quả kém hơn trong hội chứng loạn sản tủy ít nguy cơ. Sự giảm tiểu cầu kết hợp với RBC-TD sau 6 tháng cung cấp một bộ phân loại chi phí thấp và đã được xác thực về kết quả trong hội chứng loạn sản tủy ít nguy cơ.

Từ khóa


Tài liệu tham khảo

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