DnaSP, DNA polymorphism analyses by the coalescent and other methods

Bioinformatics - Tập 19 Số 18 - Trang 2496-2497 - 2003
Pascale Roux1, Juan Carlos Sánchez-DelBarrio, Xavier Messeguer, R. Rozas
1Departament de Genètica, Facultat de Biologia, Universitat de Barcelona, Diagonal 645, 08071 Barcelona, Spain. [email protected]

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Abstract Summary: DnaSP is a software package for the analysis of DNA polymorphism data. Present version introduces several new modules and features which, among other options allow: (1) handling big data sets (∼5 Mb per sequence); (2) conducting a large number of coalescent-based tests by Monte Carlo computer simulations; (3) extensive analyses of the genetic differentiation and gene flow among populations; (4) analysing the evolutionary pattern of preferred and unpreferred codons; (5) generating graphical outputs for an easy visualization of results. Availability: The software package, including complete documentation and examples, is freely available to academic users from: http://www.ub.es/dnasp

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