Distinct functions of Trio GEF domains in axon outgrowth of cerebellar granule neurons

Journal of Genetics and Genomics - Tập 46 - Trang 87-96 - 2019
Tao Tao1, Jie Sun1, Yajing Peng1, Pei Wang1, Xin Chen1, Wei Zhao1, Yeqiong Li1, Lisha Wei1, Wei Wang1, Yanyan Zheng1, Ye Wang1, Xuena Zhang1, Min-Sheng Zhu1
1Model Animal Research Center, State Key Laboratory of Pharmaceutical Biotechnology, Department of Neurology of the Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, Nanjing University, Nanjing, 210061, China

Tài liệu tham khảo

Ahmed, 2011, Draxin inhibits axonal outgrowth through the netrin receptor DCC, J. Neurosci., 31, 14018, 10.1523/JNEUROSCI.0943-11.2011

Ba, 2013, Rho GTPase signaling at the synapse: implications for intellectual disability, Exp. Cell Res., 319, 2368, 10.1016/j.yexcr.2013.05.033

Ba, 2016, TRIO loss of function is associated with mild intellectual disability and affects dendritic branching and synapse function, Hum. Mol. Genet., 25, 892, 10.1093/hmg/ddv618

Bateman, 2001, The Trio family of guanine-nucleotide-exchange factors: regulators of axon guidance, J. Cell Sci., 114, 1973, 10.1242/jcs.114.11.1973

Blangy, 2000, TrioGEF1 controls Rac- and Cdc42-dependent cell structures through the direct activation of rhoG, J. Cell Sci., 113, 729, 10.1242/jcs.113.4.729

Bradke, 1999, The role of local actin instability in axon formation, Science, 283, 1931, 10.1126/science.283.5409.1931

Briancon-Marjollet, 2008, Trio mediates netrin-1-induced Rac1 activation in axon outgrowth and guidance, Mol. Cell Biol., 28, 2314, 10.1128/MCB.00998-07

Chelly, 2006, Genetics and pathophysiology of mental retardation, Eur. J. Hum. Genet., 14, 701, 10.1038/sj.ejhg.5201595

Chen, 2007, Rac1 controls the formation of midline commissures and the competency of tangential migration in ventral telencephalic neurons, J. Neurosci., 27, 3884, 10.1523/JNEUROSCI.3509-06.2007

Chrostek, 2006, Rac1 is crucial for hair follicle integrity but is not essential for maintenance of the epidermis, Mol. Cell Biol., 26, 6957, 10.1128/MCB.00075-06

Danielian, 1998, Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase, Curr. Biol., 8, 1323, 10.1016/S0960-9822(07)00562-3

Debant, 1996, The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains, Proc. Natl. Acad. Sci. U. S. A., 93, 5466, 10.1073/pnas.93.11.5466

Demarco, 2012, The Rac GTP exchange factor TIAM-1 acts with CDC-42 and the guidance receptor UNC-40/DCC in neuronal protrusion and axon guidance, PLoS Genet., 8, e1002665, 10.1371/journal.pgen.1002665

Garvalov, 2007, Cdc42 regulates cofilin during the establishment of neuronal polarity, J. Neurosci., 27, 13117, 10.1523/JNEUROSCI.3322-07.2007

Govek, 2005, The role of the Rho GTPases in neuronal development, Genes Dev., 19, 1, 10.1101/gad.1256405

Graus-Porta, 2001, Beta1-class integrins regulate the development of laminae and folia in the cerebral and cerebellar cortex, Neuron, 31, 367, 10.1016/S0896-6273(01)00374-9

Gu, 2003, Hematopoietic cell regulation by Rac1 and Rac2 guanosine triphosphatases, Science, 302, 445, 10.1126/science.1088485

Hall, 1998, Rho GTPases and the actin cytoskeleton, Science, 279, 509, 10.1126/science.279.5350.509

Hall, 2010, Rho and Ras GTPases in axon growth, guidance, and branching, Cold Spring Harb. Perspect. Biol., 2, a001818, 10.1101/cshperspect.a001818

Herring, 2016, Kalirin and Trio proteins serve critical roles in excitatory synaptic transmission and LTP, Proc. Natl. Acad. Sci. U. S. A., 113, 2264, 10.1073/pnas.1600179113

Islam, 2009, Draxin, a repulsive guidance protein for spinal cord and forebrain commissures, Science, 323, 388, 10.1126/science.1165187

Jaffe, 2005, Rho GTPases: biochemistry and biology, Annu. Rev. Cell Dev. Biol., 21, 247, 10.1146/annurev.cellbio.21.020604.150721

Katrancha, 2017, Neurodevelopmental disease-associated de novo mutations and rare sequence variants affect TRIO GDP/GTP exchange factor activity, Hum. Mol. Genet., 26, 4728, 10.1093/hmg/ddx355

Lagenaur, 1987, An L1-like molecule, the 8D9 antigen, is a potent substrate for neurite extension, Proc. Natl. Acad. Sci. U. S. A., 84, 7753, 10.1073/pnas.84.21.7753

Li, 2008, Netrin signal transduction and the guanine nucleotide exchange factor DOCK180 in attractive signaling, Nat. Neurosci., 11, 28, 10.1038/nn2022

Li, 2002, Rac1 and Cdc42 but not RhoA or Rho kinase activities are required for neurite outgrowth induced by the Netrin-1 receptor DCC (deleted in colorectal cancer) in N1E-115 neuroblastoma cells, J. Biol. Chem., 277, 15207, 10.1074/jbc.M109913200

Li, 2002, Regulation of Rho GTPases by crosstalk and neuronal activity in vivo, Neuron, 33, 741, 10.1016/S0896-6273(02)00621-9

Liu, 2003, A highly efficient recombineering-based method for generating conditional knockout mutations, Genome Res., 13, 476, 10.1101/gr.749203

Luo, 2000, Rho GTPases in neuronal morphogenesis, Nat. Rev. Neurosci., 1, 173, 10.1038/35044547

McPherson, 2005, Multiple novel isoforms of Trio are expressed in the developing rat brain, Gene, 347, 125, 10.1016/j.gene.2004.12.028

Peng, 2010, Trio is a key guanine nucleotide exchange factor coordinating regulation of the migration and morphogenesis of granule cells in the developing cerebellum, J. Biol. Chem., 285, 24834, 10.1074/jbc.M109.096537

Pengelly, 2016, Mutations specific to the Rac-GEF domain of TRIO cause intellectual disability and microcephaly, J. Med. Genet., 53, 735, 10.1136/jmedgenet-2016-103942

Plageman, 2011, A Trio-RhoA-Shroom3 pathway is required for apical constriction and epithelial invagination, Development, 138, 5177, 10.1242/dev.067868

Portales-Casamar, 2006, Identification of novel neuronal isoforms of the Rho-GEF Trio, Biol. Cell, 98, 183, 10.1042/BC20050009

Rossman, 2005, GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors, Nat. Rev. Mol. Cell Biol., 6, 167, 10.1038/nrm1587

Sadybekov, 2017, An autism spectrum disorder-related de novo mutation hotspot discovered in the GEF1 domain of Trio, Nat. Commun., 8, 601, 10.1038/s41467-017-00472-0

Tahirovic, 2010, Rac1 regulates neuronal polarization through the WAVE complex, J. Neurosci., 30, 6930, 10.1523/JNEUROSCI.5395-09.2010

van Bokhoven, 2011, Genetic and epigenetic networks in intellectual disabilities, Annu. Rev. Genet., 45, 81, 10.1146/annurev-genet-110410-132512

Zong, 2015, Trio gene is required for mouse learning ability, Brain Res., 1608, 82, 10.1016/j.brainres.2015.02.040