Discovery and Evaluation of Entry Inhibitors for SARS-CoV-2 and Its Emerging Variants

Journal of Virology - Tập 95 Số 24 - 2021
Arpan Acharya1, Siddappa N. Byrareddy1, Michellie Thurman1, Elizabeth Klug1, Jay Trivedi1, Kalicharan Sharma2, Christian L. Lorson3,4, Kamal Singh3,4,5
1Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, Nebraska, USA
2Delhi Pharmaceutical Sciences and Research University, New Delhi, India
3Bond Life Sciences Center, University of Missouri, Columbia, Missouri, USA
4Department of Veterinary Pathobiology, University of Missouri, Columbia, Missouri, USA
5Division of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institute, Stockholm, Sweden

Tóm tắt

The ongoing coronavirus infectious disease 2019 (COVID-19) pandemic is caused by a novel coronavirus named Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). More than 207 million people have been infected globally, and 4.3 million have died due to this viral outbreak.

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