Direct inhibition by cannabinoids of human 5‐HT3A receptors: probable involvement of an allosteric modulatory site
Tóm tắt
Từ khóa
Tài liệu tham khảo
BARANN M., 2001, Inhibition by cannabinoid1 receptor agonists of currents through human 5‐HT3A receptors, Soc. Neurosci., 27, 2126
COSTALL B., 1997, Handbook of Experimental Pharmacology, 409
FAN P., 1995, Cannabinoid agonists inhibit the activation of 5‐HT3 receptors in rat nodose ganglion neurones, J. Neurophysiol., 73, 907, 10.1152/jn.1995.73.2.907
FELDER C.C., 1998, LY320135, a novel cannabinoid CB1 receptor antagonist, unmasks coupling of the CB1 receptor to stimulation of cAMP accumulation, J. Pharmacol. Exp. Ther., 284, 291
GODLEWSKI G., 2002, Inhibitory effects of cannabinoid receptor agonists on the 5‐HT3 receptor‐mediated Bezold‐Jarisch Reflex in rats and human 5‐HT3A receptors in HEK 293 cells, Naunyn Schmiedeberg's Arch. Pharmacol., 365, R28
MIYAKE A., 1995, Molecular cloning of human 5‐hydroxytryptamine3 receptor: heterogeneity in distribution and function among species, Mol. Pharmacol., 48, 407
TAO Q., 1998, Mutation of a highly conserved aspartate residue in the second transmembrane domain of the cannabinoid receptors, CB1 and CB2, disrupts G‐protein coupling, J. Pharmacol. Exp. Ther., 285, 651
THOMAS B.F., 1990, Characterization of the lipophilicity of natural and synthetic analogs of delta‐9‐tetrahydrocannabinol and its relationship to pharmacological potency, J. Pharmacol. Exp. Ther., 255, 624