Differentially expressed transcripts in adipose tissue between Korean native pig and Yorkshire breeds

Animal Genetics - Tập 40 Số 1 - Trang 115-118 - 2009
Jin-Kyoo Moon1, K.‐S. Kim2, J.‐J. Kim3, Byung Hyune Choi4, B.‐W. Cho5, Tae Hun Kim4, Cheuk Kwong Lee1
1Division of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, South Korea
2Department of Animal Science, Chungbuk National University, Cheongju, South Korea
3School of Biotechnology, Yeungnam University, Gyeongsan, South Korea
4Animal Genomics and Bioinformatics Division, National Institute of Animal Science, Suwon, South Korea
5Department of Animal Science, Busan National University, Miryang, South Korea

Tóm tắt

SummaryWe measured and compared the transcripts of adipose tissue from Korean native pig (KNP) and Yorkshire (YS) breeds to investigate breed‐specific transcription changes. We employed both the Affymetrix porcine genome array and quantitative reverse transcription‐polymerase chain reaction (qRT‐PCR). We found eight genes showing significant changes between the two breeds. Based on a literature review, these genes were indicative of differences in extracellular structure density and differences in the potential to metabolize xenobiotic chemicals and lipids. The differentially expressed genes indicated that KNP has a lower extracellular structure density and a lower potential to metabolize xenobiotic chemicals than YS.

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Tài liệu tham khảo

10.1016/j.cellsig.2005.08.009

10.1093/toxsci/55.2.284

10.1016/j.febslet.2006.06.058

10.1042/BJ20021698

Jeon J.T., 2003, A large‐insert porcine library with sevenfold genome coverage: a tool for positional cloning of candidate genes for major quantitative traits, Molecules and Cells, 16, 113, 10.1016/S1016-8478(23)13774-5

10.1266/ggs.77.361

10.1111/j.1439-0388.2005.00518.x

10.2527/2005.83102255x

10.1093/nar/gki064

10.1074/jbc.M609692200

10.1111/j.1365-2052.2004.01140.x

10.1016/S0168-9525(02)02665-3

10.1016/j.abb.2004.02.036

10.1074/jbc.M206363200

10.1194/jlr.M400362-JLR200

10.1111/j.1365-2052.2006.01460.x

10.1186/1471-2164-7-328

10.7150/ijbs.3.132

10.1093/jn/136.2.337

10.1016/j.ygeno.2005.08.001

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Thông tin xuất bản

Animal Genetics

Tập 40 Số 1

115-118

Thông tin tác giả