Nội dung được dịch bởi AI, chỉ mang tính chất tham khảo
Các phương pháp cấp nước khác nhau để phòng ngừa bệnh thận do thuốc cản quang ở bệnh nhân can thiệp động mạch vành qua da theo kế hoạch: một nghiên cứu hồi cứu
Tóm tắt
Cấp nước hiện đang là biện pháp chính để ngăn ngừa bệnh thận do thuốc cản quang (CIN). Mục tiêu của chúng tôi là so sánh hiệu quả phòng ngừa của việc cấp nước trước và sau thủ thuật đối với CIN ở những bệnh nhân mắc bệnh tim mạch vành đang tiến hành can thiệp động mạch vành qua da (PCI) theo kế hoạch. Một nghiên cứu hồi cứu đã bao gồm 198 trường hợp cấp nước sau thủ thuật và 396 trường hợp cấp nước trước thủ thuật bằng cách sử dụng khớp tỷ lệ xu hướng. Tỷ lệ CIN 48 giờ sau PCI và các biến cố bất lợi trong vòng 30 ngày sau khi tiếp xúc với thuốc cản quang đã được so sánh giữa hai nhóm. Phân tích hồi quy logistic đã được sử dụng để phân tích các yếu tố nguy cơ của CIN. Tỷ lệ CIN trong nhóm cấp nước sau thủ thuật là 3,54%, trong khi tỷ lệ ở nhóm cấp nước trước thủ thuật là 4,8%. Không có sự khác biệt đáng kể giữa hai nhóm (p = 0,478). Phân tích hồi quy logistic đa biến cho thấy tiểu đường, mức BNP cơ bản và mức cystatin C, cũng như liều lượng thuốc cản quang là các yếu tố nguy cơ độc lập đối với CIN. Không có sự khác biệt đáng kể về tỷ lệ các biến cố bất lợi lớn giữa hai nhóm (3,03% so với 2,02%, p = 0,830). Cấp nước sau thủ thuật có hiệu quả tương đương so với cấp nước trước phẫu thuật trong việc phòng ngừa CIN ở bệnh nhân bệnh tim mạch vành đang tiến hành PCI theo kế hoạch.
Từ khóa
#cấp nước #bệnh thận do thuốc cản quang #can thiệp động mạch vành qua da #bệnh tim mạch vành #nghiên cứu hồi cứuTài liệu tham khảo
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