Dietary Oxalate Intake and Kidney Outcomes

Nutrients - Tập 12 Số 9 - Trang 2673
Matteo Bargagli1,2, Maria Clarissa Tio3, Sushrut S. Waikar4, Pietro Manuel Ferraro1,2
1U.O.C. Nefrologia, Dipartimento di Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Roma, Italy
2Università Cattolica del Sacro Cuore, 00168, Roma, Italy
3Division of Renal Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02101, USA
4Renal Section, Department of Medicine, Boston University School of Medicine and Boston Medical Center, Boston, MA 02101, USA

Tóm tắt

Oxalate is both a plant-derived molecule and a terminal toxic metabolite with no known physiological function in humans. It is predominantly eliminated by the kidneys through glomerular filtration and tubular secretion. Regardless of the cause, the increased load of dietary oxalate presented to the kidneys has been linked to different kidney-related conditions and injuries, including calcium oxalate nephrolithiasis, acute and chronic kidney disease. In this paper, we review the current literature on the association between dietary oxalate intake and kidney outcomes.

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Tài liệu tham khảo

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