Diagnostics of autoimmune encephalitis associated with antibodies against neuronal surface antigens

Neurological Sciences - Tập 38 - Trang 225-229 - 2017
Luigi Zuliani1, Marco Zoccarato2, Matteo Gastaldi3, Raffaele Iorio4, Amelia Evoli4, Tiziana Biagioli5, Silvia Casagrande5, Elena Bazzigaluppi6, Raffaella Fazio6, Claudia Giannotta7, Eduardo Nobile-Orazio7, Francesca Andreetta8, Ornella Simoncini8, Gianna Costa9, Sara Mariotto10, Sergio Ferrari10, Elisabetta Galloni11, Michela Marcon11, Diego Franciotta12, Bruno Giometto2
1Ospedale Ca’ Foncello AULSS2 Marca Trevigiana, Treviso, Italy
2Ospedale S. Antonio AULSS Euganea, Padua, Italy
3C. Mondino National Neurological Institute, University of Pavia, Pavia, Italy
4Policlinico A. Gemelli, Università Cattolica del Sacro Cuore, Rome, Italy
5AOU Careggi, Florence, Italy
6Ospedale San Raffaele, Milan, Italy
7Humanitas Clinical Institute, Milan University, Milan, Italy
8C. Besta Neurological Institute, Milan, Italy
9Ospedale R. Binaghi, Cagliari, Italy
10Department of Neuroscience, Biomedicine and Movement, University of Verona, Verona, Italy
11Ospedale S. Bortolo, Vicenza, Italy
12C. Mondino National Neurological Institute, Pavia, Italy

Tóm tắt

This document presents the guidelines for testing antibodies against neuronal surface antigens that have been developed following a consensus process built on questionnaire-based surveys, internet contacts, and discussions at workshops of the sponsoring Italian Association of Neuroimmunology (AINI) congresses. Essential clinical information on autoimmune encephalitis associated with antibodies against neuronal surface antigens, indications and limits of testing for such antibodies, instructions for result interpretation, and an agreed laboratory protocol (Appendix A) are reported for the communicative community of neurologists and clinical pathologists.

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