Developmental Competence for Primordial Germ Cell Fate

Current Topics in Developmental Biology - Tập 117 - Trang 471-496 - 2016
Ufuk Günesdogan1,2, M. Azim Surani1,2
1Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, United Kingdom
2Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom

Tài liệu tham khảo

Adachi, 2013, Context-dependent wiring of Sox2 regulatory networks for self-renewal of embryonic and trophoblast stem cells, Molecular Cell, 52, 380, 10.1016/j.molcel.2013.09.002 Ancelin, 2006, Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells, Nature Cell Biology, 8, 623, 10.1038/ncb1413 Aramaki, 2013, A mesodermal factor, T, specifies mouse germ cell fate by directly activating germline determinants, Developmental Cell, 27, 516, 10.1016/j.devcel.2013.11.001 Arnold, 2009, Making a commitment: Cell lineage allocation and axis patterning in the early mouse embryo, Nature Reviews. Molecular Cell Biology, 10, 91, 10.1038/nrm2618 Auman, 2002, Transcription factor AP-2gamma is essential in the extra-embryonic lineages for early postimplantation development, Development, 129, 2733, 10.1242/dev.129.11.2733 Ben-Haim, 2006, The nodal precursor acting via activin receptors induces mesoderm by maintaining a source of its convertases and BMP4, Developmental Cell, 11, 313, 10.1016/j.devcel.2006.07.005 Bikoff, 2009, An expanding job description for Blimp-1/PRDM1, Current Opinion in Genetics & Development, 19, 379, 10.1016/j.gde.2009.05.005 Boroviak, 2014, The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification, Nature Cell Biology, 16, 516, 10.1038/ncb2965 Brennan, 2001, Nodal signalling in the epiblast patterns the early mouse embryo, Nature, 411, 965, 10.1038/35082103 Brons, 2007, Derivation of pluripotent epiblast stem cells from mammalian embryos, Nature, 448, 191, 10.1038/nature05950 Buecker, 2014, Reorganization of enhancer patterns in transition from naive to primed pluripotency, Cell Stem Cell, 14, 838, 10.1016/j.stem.2014.04.003 Burton, 2013, Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo, Cell Reports, 5, 687, 10.1016/j.celrep.2013.09.044 Calo, 2013, Modification of enhancer chromatin: What, how, and why?, Molecular Cell, 49, 825, 10.1016/j.molcel.2013.01.038 Campolo, 2013, Essential role of Sox2 for the establishment and maintenance of the germ cell line, Stem Cells, 31, 1408, 10.1002/stem.1392 Chan, 2013, A PRC2-dependent repressive role of PRDM14 in human embryonic stem cells and induced pluripotent stem cell reprogramming, Stem Cells, 31, 682, 10.1002/stem.1307 Ciruna, 1997, Chimeric analysis of fibroblast growth factor receptor-1 (Fgfr1) function: A role for FGFR1 in morphogenetic movement through the primitive streak, Development, 124, 2829, 10.1242/dev.124.14.2829 Conlon, 1994, A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse, Development, 120, 1919, 10.1242/dev.120.7.1919 Creyghton, 2010, Histone H3K27ac separates active from poised enhancers and predicts developmental state, Proceedings of the National Academy of Sciences of the United States of America, 107, 21931, 10.1073/pnas.1016071107 de Mochel, 2015, BMP signaling regulates both cell proliferation and ICM lineage commitment in preimplantation-stage mouse embryos, Developmental Biology, 397, 45, 10.1016/j.ydbio.2014.10.001 Dunn, 2004, Combinatorial activities of Smad2 and Smad3 regulate mesoderm formation and patterning in the mouse embryo, Development, 131, 1717, 10.1242/dev.01072 Durcova-Hills, 2001, Pluripotential stem cells derived from migrating primordial germ cells, Differentiation, 68, 220, 10.1046/j.1432-0436.2001.680409.x Durcova-Hills, 2008, Reprogramming primordial germ cells into pluripotent stem cells, PLoS One, 3, e3531, 10.1371/journal.pone.0003531 Evans, 1981, Establishment in culture of pluripotential cells from mouse embryos, Nature, 292, 154, 10.1038/292154a0 Factor, 2014, Epigenomic comparison reveals activation of “seed” enhancers during transition from naive to primed pluripotency, Stem Cell, 14, 854 Gafni, 2013, Derivation of novel human ground state naive pluripotent stem cells, Nature, 504, 282, 10.1038/nature12745 Gao, 2008, Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development, Genes & Development, 22, 3435, 10.1101/gad.1752608 Ghavi-Helm, 2014, Enhancer loops appear stable during development and are associated with paused polymerase, Nature, 512, 96, 10.1038/nature13417 Grabole, 2013, Prdm14 promotes germline fate and naive pluripotency by repressing FGF signalling and DNA methylation, EMBO Reports, 14, 629, 10.1038/embor.2013.67 Graham, 2014, BMP signalling regulates the pre-implantation development of extra-embryonic cell lineages in the mouse embryo, Nature Communications, 5, 5667, 10.1038/ncomms6667 Günesdogan, 2010, A genetic system to assess in vivo the functions of histones and histone modifications in higher eukaryotes, EMBO Reports, 11, 772, 10.1038/embor.2010.124 Gyory, 2004, PRDI-BF1 recruits the histone H3 methyltransferase G9a in transcriptional silencing, Nature Immunology, 5, 299, 10.1038/ni1046 Hackett, 2013, Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine, Science, 339, 448, 10.1126/science.1229277 Hackett, 2013, DNA methylation dynamics during the mammalian life cycle, Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences, 368, 10.1098/rstb.2011.0328 Hajkova, 2008, Chromatin dynamics during epigenetic reprogramming in the mouse germ line, Nature, 452, 877, 10.1038/nature06714 Han, 2010, Epiblast stem cell subpopulations represent mouse embryosof distinct pregastrulation stages, Cell, 143, 617, 10.1016/j.cell.2010.10.015 Hayashi, 2012, Offspring from oocytes derived from in vitro primordial germ cell-like cells in mice, Science, 338, 971, 10.1126/science.1226889 Hayashi, 2011, Reconstitution of the mouse germ cell specification pathway in culture by pluripotent stem cells, Cell, 146, 519, 10.1016/j.cell.2011.06.052 Hayashi, 2009, Self-renewing epiblast stem cells exhibit continual delineation of germ cells with epigenetic reprogramming in vitro, Development, 136, 3549, 10.1242/dev.037747 Heintzman, 2007, Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome, Nature Genetics, 39, 311, 10.1038/ng1966 Hilton, 2015, Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers, Nature Biotechnology, 33, 510, 10.1038/nbt.3199 Holmqvist, 2014, Genomic occupancy of the transcriptional co-activators p300 and CBP, Transcription, 4, 18, 10.4161/trns.22601 Irie, 2015, SOX17 is a critical specifier of human primordial germ cell fate, Cell, 160, 253, 10.1016/j.cell.2014.12.013 Johansson, 1995, Evidence for involvement of activin A and bone morphogenetic protein 4 in mammalian mesoderm and hematopoietic development, Molecular and Cellular Biology, 15, 141, 10.1128/MCB.15.1.141 Kearns, 2015, Functional annotation of native enhancers with a Cas9-histone demethylase fusion, Nature Methods, 12, 401, 10.1038/nmeth.3325 Keller, 1991, Identification and characterization of a novel repressor of beta-interferon gene expression, Genes & Development, 5, 868, 10.1101/gad.5.5.868 Kelly, 2004, The Wnt co-receptors Lrp5 and Lrp6 are essential for gastrulation in mice, Development, 131, 2803, 10.1242/dev.01137 Kojima, 2014, The transcriptional and functional properties of mouse epiblast stem cells resemble the anterior primitive streak, Cell Stem Cell, 14, 107, 10.1016/j.stem.2013.09.014 Kuckenberg, 2012, The role of transcription factor Tcfap2c/TFAP2C in trophectoderm development, Reproductive BioMedicine Online, 25, 12, 10.1016/j.rbmo.2012.02.015 Kunath, 2005, Imprinted X-inactivation in extra-embryonic endoderm cell lines from mouse blastocysts, Development, 132, 1649, 10.1242/dev.01715 Kurimoto, 2015, Quantitative dynamics of chromatin remodeling during germ cell specification from mouse embryonic stem cells, Cell Stem Cell, 16, 517, 10.1016/j.stem.2015.03.002 Kurimoto, 2008, Complex genome-wide transcription dynamics orchestrated by Blimp1 for the specification of the germ cell lineage in mice, Genes & Development, 22, 1617, 10.1101/gad.1649908 Lara-Astiaso, 2014, Chromatin state dynamics during blood formation, Science, 345, 943, 10.1126/science.1256271 Lawson, 1999, Bmp4 is required for the generation of primordial germ cells in the mouse embryo, Genes & Development, 13, 424, 10.1101/gad.13.4.424 Lee, 2011, Graded nodal/activin signaling titrates conversion of quantitative phospho-Smad2 levels into qualitative embryonic stem cell fate decisions, PLoS Genetics, 7, e1002130, 10.1371/journal.pgen.1002130 Leitch, 2010, Embryonic germ cells from mice and rats exhibit properties consistent with a generic pluripotent ground state, Development, 137, 2279, 10.1242/dev.050427 Leitch, 2014, On the fate of primordial germ cells injected into early mouse embryos, Developmental Biology, 385, 155, 10.1016/j.ydbio.2013.11.014 Li, 2009, Foxa1 and Foxa2 regulate bile duct development in mice, The Journal of Clinical Investigation, 119, 1537, 10.1172/JCI38201 Liu, 1999, Requirement for Wnt3 in vertebrate axis formation, Nature Genetics, 22, 361, 10.1038/11932 Ma, 2011, Sequence-specific regulator Prdm14 safeguards mouse ESCs from entering extraembryonic endoderm fates, Nature Publishing Group, 18, 120 Magnúsdóttir, 2013, A tripartite transcription factor network regulates primordial germ cell specification in mice, Nature Cell Biology, 15, 905, 10.1038/ncb2798 Martin, 1981, Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells, Proceedings of the National Academy of Sciences of the United States of America, 78, 7634, 10.1073/pnas.78.12.7634 Matsui, 1992, Derivation of pluripotential embryonic stem cells from murine primordial germ cells in culture, Cell, 70, 841, 10.1016/0092-8674(92)90317-6 Mendenhall, 2013, Locus-specific editing of histone modifications at endogenous enhancers, Nature Biotechnology, 31, 1133, 10.1038/nbt.2701 Mishina, 1995, Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis, Genes & Development, 9, 3027, 10.1101/gad.9.24.3027 Mould, 2012, Blimp1/Prdm1 governs terminal differentiation of endovascular trophoblast giant cells and defines multipotent progenitors in the developing placenta, Genes & Development, 26, 2063, 10.1101/gad.199828.112 Mullen, 2011, Master transcription factors determine cell-type-specific responses to TGF-b signaling, Cell, 147, 565, 10.1016/j.cell.2011.08.050 Nagamatsu, 2015, Integrative analysis of the acquisition of pluripotency in PGCs reveals the mutually exclusive roles of Blimp-1 and AKT signaling, Stem Cell Reports, 5, 111, 10.1016/j.stemcr.2015.05.007 Nakaki, 2013, Induction of mouse germ-cell fate by transcription factors in vitro, Nature, 501, 222, 10.1038/nature12417 Nakaki, 2014, PRDM14: A unique regulator for pluripotency and epigenetic reprogramming, Trends in Biochemical Sciences, 39, 289, 10.1016/j.tibs.2014.04.003 Ohinata, 2009, A signaling principle for the specification of the germ cell lineage in mice, Cell, 137, 571, 10.1016/j.cell.2009.03.014 Ohinata, 2005, Blimp1 is a critical determinant of the germ cell lineage in mice, Nature, 436, 207, 10.1038/nature03813 Okashita, 2013, PRDM14 promotes active DNA demethylation through the Ten-eleven translocation (TET)-mediated base excision repair pathway in embryonic stem cells, Development, 141, 269, 10.1242/dev.099622 Papp, 2013, Epigenetics of reprogramming to induced pluripotency, Cell, 152, 1324, 10.1016/j.cell.2013.02.043 Payer, 2013, Tsix RNA and the germline factor, PRDM14, link X reactivation and stem cell reprogramming, Molecular Cell, 52, 805, 10.1016/j.molcel.2013.10.023 Pirouz, 2013, A critical function of Mad2l2 in primordial germ cell development of mice, PLoS Genetics, 9, e1003712, 10.1371/journal.pgen.1003712 Pouponnot, 1998, Physical and functional interaction of SMADs and p300/CBP, The Journal of Biological Chemistry, 273, 22865, 10.1074/jbc.273.36.22865 Powell, 2013, Prdm1a directly activates foxd3 and tfap2a during zebrafish neural crest specification, Development, 140, 3445, 10.1242/dev.096164 Resnick, 1992, Long-term proliferation of mouse primordial germ cells in culture, Nature, 359, 550, 10.1038/359550a0 Sasaki, 2015, Robust in vitro induction of human germ cell fate from pluripotent stem cells, Cell Stem Cell, 17, 178, 10.1016/j.stem.2015.06.014 Schemmer, 2013, Transcription factor TFAP2C regulates major programs required for murine fetal germ cell maintenance and haploinsufficiency predisposes to teratomas in male mice, PLoS One, 8, e71113, 10.1371/journal.pone.0071113 Schoenfelder, 2015, The pluripotent regulatory circuitry connecting promoters to their long-range interacting elements, Genome Research, 25, 582, 10.1101/gr.185272.114 Schoenfelder, 2015, Polycomb repressive complex PRC1 spatially constrains the mouse embryonic stem cell genome, Nature Genetics, 47, 1179, 10.1038/ng.3393 Seki, 2007, Cellular dynamics associated with the genome-wide epigenetic reprogramming in migrating primordial germ cells in mice, Development, 134, 2627, 10.1242/dev.005611 Shovlin, 2008, Heterogeneity in imprinted methylation patterns of pluripotent embryonic germ cells derived from pre-migratory mouse germ cells, Developmental Biology, 313, 674, 10.1016/j.ydbio.2007.11.007 Spitz, 2012, Transcription factors: From enhancer binding to developmental control, Nature Reviews. Genetics, 13, 613, 10.1038/nrg3207 Stevens, 1967, Origin of testicular teratomas from primordial germ cells in mice, Journal of the National Cancer Institute, 38, 549 Su, 2009, Involvement of histone demethylase LSD1 in Blimp-1-mediated gene repression during plasma cell differentiation, Molecular and Cellular Biology, 29, 1421, 10.1128/MCB.01158-08 Sugawa, 2015, Human primordial germ cell commitment in vitro associates with a unique PRDM14 expression profile, The EMBO Journal, 34, 1009, 10.15252/embj.201488049 Sugimoto, 2015, A simple and robust method for establishing homogeneous mouse epiblast stem cell lines by wnt inhibition, Stem Cell Reports, 4, 744, 10.1016/j.stemcr.2015.02.014 Sumi, 2013, Epiblast ground state is controlled by canonical Wnt/β-catenin signaling in the postimplantation mouse embryo and epiblast stem cells, PLoS One, 8, e63378, 10.1371/journal.pone.0063378 Tada, 1998, Epigenotype switching of imprintable loci in embryonic germ cells, Development Genes and Evolution, 207, 551, 10.1007/s004270050146 Tam, 1996, The allocation of epiblast cells to ectodermal and germ-line lineages is influenced by the position of the cells in the gastrulating mouse embryo, Developmental Biology, 178, 124, 10.1006/dbio.1996.0203 Tanaka, 1998, Promotion of trophoblast stem cell proliferation by FGF4, Science, 282, 2072, 10.1126/science.282.5396.2072 Tesar, 2007, New cell lines from mouse epiblast share defining features with human embryonic stem cells, Nature, 448, 196, 10.1038/nature05972 Tsakiridis, 2014, Distinct Wnt-driven primitive streak-like populations reflect in vivo lineage precursors, Development, 141, 1209, 10.1242/dev.101014 Vincent, 2005, The zinc finger transcriptional repressor Blimp1/Prdm1 is dispensable for early axis formation but is required for specification of primordial germ cells in the mouse, Development, 132, 1315, 10.1242/dev.01711 Visel, 2009, ChIP-seq accurately predicts tissue-specific activity of enhancers, Nature, 457, 854, 10.1038/nature07730 Wan, 2005, Compensatory roles of Foxa1 and Foxa2 during lung morphogenesis, The Journal of Biological Chemistry, 280, 13809, 10.1074/jbc.M414122200 Wang, 2015, Epigenetic priming of enhancers predicts developmental competence of hESC-derived endodermal lineage intermediates, Cell Stem Cell, 16, 386, 10.1016/j.stem.2015.02.013 Wang, 2012, Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors, Genome Research, 22, 1798, 10.1101/gr.139105.112 Weber, 2010, Critical function of AP-2 gamma/TCFAP2C in mouse embryonic germ cell maintenance, Biology of Reproduction, 82, 214, 10.1095/biolreprod.109.078717 Werling, 2002, Transcription factor gene AP-2 gamma essential for early murine development, Molecular and Cellular Biology, 22, 3149, 10.1128/MCB.22.9.3149-3156.2002 Winnier, 1995, Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse, Genes & Development, 9, 2105, 10.1101/gad.9.17.2105 Yamaguchi, 1994, fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation, Genes & Development, 8, 3032, 10.1101/gad.8.24.3032 Yamaji, 2008, Critical function of Prdm14 for the establishment of the germ cell lineage in mice, Nature Genetics, 40, 1016, 10.1038/ng.186 Yamaji, 2013, PRDM14 ensures naive pluripotency through dual regulation of signaling and epigenetic pathways in mouse embryonic stem cells, Cell Stem Cell, 12, 368, 10.1016/j.stem.2012.12.012 Yang, 2014, Otx2 and Oct4 drive early enhancer activation during embryonic stem cell transition from naive pluripotency, Cell Reports, 7, 1968, 10.1016/j.celrep.2014.05.037 Ying, 2008, The ground state of embryonic stem cell self-renewal, Nature, 453, 519, 10.1038/nature06968 Yu, 2000, Transcriptional repression by blimp-1 (PRDI-BF1) involves recruitment of histone deacetylase, Molecular and Cellular Biology, 20, 2592, 10.1128/MCB.20.7.2592-2603.2000 Zaret, 2011, Pioneer transcription factors: Establishing competence for gene expression, Genes & Development, 25, 2227, 10.1101/gad.176826.111