Determination of Trace Sulfonamides in Environmental Water and Milk Through Capillary Electrochromatography Using PEG-MoS2 as Stationary Phase

In this work, a composite of polyethylene glycol (PEG) modified MoS2 (PEG-MoS2) was synthesized and used as the stationary phase of open-tubular capillary column via a chemical bonding strategy. The PEG-MoS2 exhibited a sphere-like architecture through characterization of scanning electronic microscopy. p-phenylenediboronic acid was introduced as a linker to combine the PEG-MoS2 with capillary column. A capillary electrochromatographic method was established for the determination of nine sulfonamides by using PEG-MoS2-coated capillary column. The intra-day, inter-day, and column-to-column relative standard deviations (RSDs) of migration time and peak area were in the range of 0.80–4.38% and 1.61–9.22%, respectively. The limits of detection were in the range of 20.4–64.8 ng/mL. The recoveries in environmental water and milk were from 83.26 to 116.29% and 80.86 to 118.22%. This work is the first report that PEG-MoS2 material is utilized as stationary phase for capillary electrochromatography.