Datamonkey 2010: a suite of phylogenetic analysis tools for evolutionary biology

Bioinformatics - Tập 26 Số 19 - Trang 2455-2457 - 2010
Wayne Delport1, Art F. Y. Poon1, Simon D. W. Frost1, Sergei L. Kosakovsky Pond1
11 Department of Pathology, Antiviral Research Center, University of California, San Diego, CA, USA, 2British Columbia Centre for Excellence in HIV/AIDS, Vancouver, British Columbia, Canada, 3Department of Veterinary Medicine, University of Cambridge, Cambridge, UK and 4Department of Medicine, Antiviral Research Center, University of California, San Diego, CA, USA

Tóm tắt

Abstract Summary: Datamonkey is a popular web-based suite of phylogenetic analysis tools for use in evolutionary biology. Since the original release in 2005, we have expanded the analysis options to include recently developed algorithmic methods for recombination detection, evolutionary fingerprinting of genes, codon model selection, co-evolution between sites, identification of sites, which rapidly escape host-immune pressure and HIV-1 subtype assignment. The traditional selection tools have also been augmented to include recent developments in the field. Here, we summarize the analyses options currently available on Datamonkey, and provide guidelines for their use in evolutionary biology. Availability and documentation:  http://www.datamonkey.org Contact:  [email protected]

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