DOI disrupts prepulse inhibition of startle in rats via 5-HT2A receptors in the ventral pallidum

Appel, 1990, Autoradiographic characterization of (±)-1-(2,5-dimethoxy-4-[125I]iodophenyl)-2-aminopropane ([125I]DOI) binding to 5-HT2 and 5-HT1c receptors in rat brain, J. Pharmacol. Exp. Ther., 255, 843

Braff, 1992, Gating and habituation of the startle reflex in schizophrenic patients, Arch. Gen. Psychiatry, 49, 206, 10.1001/archpsyc.1992.01820030038005

Cools, 1980, Role of neostriatal dopaminergic activity in sequencing and selecting behavioral strategies: facilitation of processes involved in selecting the best strategy in a stressful situation, Behav. Brain Res., 1, 361, 10.1016/0166-4328(80)90035-2

Ebert, 1991, The mesencephalic locomotor region is activated during the auditory startle response of the unrestrained rat, Brain Res., 565, 209, 10.1016/0006-8993(91)91651-G

Geyer, M.A. and Markou, A., Animal models of psychiatric disorders, in: F.E. Bloom, D.J. Kupfer (Eds.), Psychopharmacology: the Fourth Generation of Progress, Raven Press, New York, NY, 1995, pp. 787–798.

Graham, 1975, The more or less startling effects of weak prestimuli, Psychophysiology, 12, 238, 10.1111/j.1469-8986.1975.tb01284.x

Groenewegen, 1993, Organization of the output of the ventral striatopallidal system in the rat: ventral pallidal efferents, Neuroscience, 57, 113, 10.1016/0306-4522(93)90115-V

Haber, 1985, Efferent connections of the ventral pallidum: evidence of a dual striatopallidofugal pathway, J. Comp. Neurol., 235, 322, 10.1002/cne.902350304

Insel, 1992, Toward a neuroanatomy of obsessive-compulsive disorder, Arch. Gen. Psychiatry, 49, 739, 10.1001/archpsyc.1992.01820090067011

Joyce, 1993, Serotonin uptake sites and serotonin receptors are altered in the limbic system of schizophrenics, Neuropsychopharmacology, 8, 315, 10.1038/npp.1993.32

Kehne, 1996, Preclinical characterization of the potential of the putative atypical antipsychotic MDL 100,907 as a potent 5-HT2A antagonist with a favorable CNS safety profile, J. Pharmacol. Exp. Ther., 277, 968

Koch, 1993, Cholinergic neurons in the pedunculopontine tegmental nucleus are involved in the mediation of prepulse inhibition of the acoustic startle response in the rat, Exp. Brain Res., 97, 71, 10.1007/BF00228818

Kodsi, 1994, Quinolinic acid lesions of the ventral striatum reduce sensorimotor gating of acoustic startle in rats, Brain Res., 643, 59, 10.1016/0006-8993(94)90008-6

Leitner, 1981, Midbrain reticular formation involved in the inhibition of acoustic startle, Physiol. Behav., 26, 259, 10.1016/0031-9384(81)90021-4

Lingenhohl, 1994, Giant neurons in the rat reticular formation: a sensorimotor interface in the elementary acoustic startle circuit?, J. Neurosci., 14, 1176, 10.1523/JNEUROSCI.14-03-01176.1994

Mansbach, 1989, Prepulse inhibition of the acoustic startle response is disrupted by N-ethyl-3,4-methylenedioxyamphetamine (MDEA) in the rat, Eur. J. Pharmacol., 167, 49, 10.1016/0014-2999(89)90746-2

Martinez, 1997, Characterization of the disruptions of prepulse inhibition and habituation of startle induced by α-ethyltryptamine, Neuropsychopharmacology, 16, 246, 10.1016/S0893-133X(96)00240-0

Meltzer, 1991, The mechanism of action of novel antipsychotic drugs, Schizophr. Bull., 17, 263, 10.1093/schbul/17.2.263

Mink, 1993, Basal ganglia intrinsic circuits and their role in behavior, Curr. Opin. Neurobiol., 3, 950, 10.1016/0959-4388(93)90167-W

Morilak, 1993, Immunocytochemical localization and description of neurons expressing serotonin2 receptors in the rat brain, Neuroscience, 54, 701, 10.1016/0306-4522(93)90241-7

Morilak, 1994, Neurons expressing 5-HT2 receptors in the rat brain: neurochemical identification of cell types by immunocytochemistry, Neuropsychopharmacology, 11, 157, 10.1038/sj.npp.1380102

Nauta, 1978, Efferent connections and nigral afferents of the nucleus accumbens septi in the rat, Neuroscience, 3, 385, 10.1016/0306-4522(78)90041-6

Nozulak, J., Kalkman, H., Floersheim, P., Hoyer, D. and Buerki, H.R., SDZ SER 082, a centrally acting and selective 5-HT2C antagonist, Soc. Neurosci. Abstr., 126.11 (1993).

Padich, 1996, 5-HT modulation of auditory and visual sensorimotor gating., Psychopharmacology, 124, 107, 10.1007/BF02245610

Paxinos, G. and Watson, C., The Rat Brain in Stereotaxic Coordinates, 2nd edn., Academic Press, San Diego, CA, 1986.

Penney, 1983, Speculations on the functional anatomy of basal ganglia disorders, Annu. Rev. Neurosci., 6, 73, 10.1146/annurev.ne.06.030183.000445

Rigdon, 1992, 5-Hydroxytryptamine-1a receptor agonists block prepulse inhibition of acoustic startle reflex, J. Pharmacol. Exp. Ther., 263, 486

Robbins, 1982, Functional studies of central catecholamines, Int. Rev. Neurobiol., 23, 303, 10.1016/S0074-7742(08)60628-5

Sipes, 1994, Multiple serotonin receptor subtypes modulate prepulse inhibition of the startle response in rats, Neuropharmacology, 33, 441, 10.1016/0028-3908(94)90074-4

Sipes, 1995, 8-OH-DPAT disruption of prepulse inhibition in the rat: localization of site of action with WAY 100,135, Psychopharmacology, 117, 41, 10.1007/BF02245096

Sipes, 1995, DOI disruption of prepulse inhibition in the rat is mediated by 5-HT2A and not by 5-HT2C receptors, Behav. Pharmacol., 6, 839, 10.1097/00008877-199512000-00010

Sorensen, 1993, Characterization of the 5-HT2 receptor antagonist MDL 100907 as a putative atypical antipsychotic: behavioral, electrophysiological and neurochemical studies, J. Pharmacol. Exp. Ther., 266, 684

Swerdlow, 1993, A preliminary assessment of sensorimotor gating in patients with obsessive compulsive disorder, Biol. Psychiatry, 33, 298, 10.1016/0006-3223(93)90300-3

Swerdlow, N.R., Braff, D.L., Caine, S.B., Geyer M.A., Limbic cortico-striato-pallido-pontine substrates of sensorimotor gating in animal models and psychiatric disorders, in: P.W. Kalivas, C.D. Barnes (Eds.), Limbic Motor Circuits and Neuropsychiatry, CRC Press, Boca Raton, FL, 1993, pp. 311–328.

Swerdlow, 1990, GABAergic projection from nucleus accumbens to ventral pallidum mediates dopamine-induced sensorimotor gating deficits of acoustic startle in rats, Brain Res., 532, 146, 10.1016/0006-8993(90)91754-5

Swerdlow, 1986, Central dopamine hyperactivity in rats mimics abnormal acoustic startle response in schizophrenics, Biol. Psychiatry, 21, 23, 10.1016/0006-3223(86)90005-3

Swerdlow, 1993, Prepulse inhibition of acoustic startle in rats after lesions of the pedunculopontine tegmental nucleus, Behav. Neurosci., 107, 104, 10.1037/0735-7044.107.1.104

Swerdlow, 1995, Impaired prepulse inhibition of acoustic startle and tactile startle response in patients with Huntington's disease, J. Neurol. Neurosurg. Psychiatry, 58, 192, 10.1136/jnnp.58.2.192

Winslow, 1990, Neurobiology of obsessive compulsive disorder: a possible role for serotonin, J. Clin. Psychiatry, 51, 27

Wu, 1989, Lateral geniculate spikes, muscle atonia and startle response elicited by auditory stimuli as a function of stimulus parameters and arousal state, Brain Res., 499, 7, 10.1016/0006-8993(89)91130-X

Wu, 1988, Anatomical distribution and response patterns of reticular neurons active in relation to acoustic startle, Brain Res., 457, 399, 10.1016/0006-8993(88)90716-0