DARPins: An Efficient Targeting Domain for Lentiviral Vectors

Cockrell, 2007, Gene delivery by lentivirus vectors, Mol Biotechnol, 36, 184, 10.1007/s12033-007-0010-8

Naldini, 2009, Medicine. A comeback for gene therapy, Science, 326, 805, 10.1126/science.1181937

Frecha, 2008, Strategies for targeting lentiviral vectors, Curr Gene Ther, 8, 449, 10.2174/156652308786848003

Buchholz, 2009, Lentiviral vectors with measles virus glycoproteins - dream team for gene transfer?, Trends Biotechnol, 27, 259, 10.1016/j.tibtech.2009.02.002

Morizono, 2005, Lentiviral vector retargeting to P-glycoprotein on metastatic melanoma through intravenous injection, Nat Med, 11, 346, 10.1038/nm1192

Morizono, 2009, A versatile targeting system with lentiviral vectors bearing the biotin-adaptor peptide, J Gene Med, 11, 655, 10.1002/jgm.1345

Morizono, 2009, Redirecting lentiviral vectors by insertion of integrin-tageting peptides into envelope proteins, J Gene Med, 11, 549, 10.1002/jgm.1339

Yanagi, 2006, Measles virus: cellular receptors, tropism and pathogenesis, J Gen Virol, 87, 2767, 10.1099/vir.0.82221-0

Funke, 2008, Targeted cell entry of lentiviral vectors, Mol Ther, 16, 1427, 10.1038/mt.2008.128

Anliker, 2010, Specific gene transfer to neurons, endothelial cells and hematopoetic progenitors with lentiviral vectors, Nat Methods, 7, 929, 10.1038/nmeth.1514

Sedgwick, 1999, The ankyrin repeat: a diversity of interactions on a common structural framework, Trends Biochem Sci, 24, 311, 10.1016/S0968-0004(99)01426-7

Kohl, 2003, Designed to be stable: crystal structure of a consensus ankyrin repeat protein, Proc Natl Acad Sci USA, 100, 1700, 10.1073/pnas.0337680100

Binz, 2004, High-affinity binders selected from designed ankyrin repeat protein libraries, Nat Biotechnol, 22, 575, 10.1038/nbt962

Yarden, 2001, Biology of HER2 and its importance in breast cancer, Oncology, 61, 1, 10.1159/000055396

Zahnd, 2007, A designed ankyrin repeat protein evolved to picomolar affinity to Her2, J Mol Biol, 369, 1015, 10.1016/j.jmb.2007.03.028

Steiner, 2008, Efficient selection of DARPins with sub nanomolar affinities using SRP phage display, J Mol Biol, 382, 1211, 10.1016/j.jmb.2008.07.085

Ramm, 1999, Removal of the conserved disulfide bridges from the scFv fragment of an antibody: effects on folding kinetics and aggregation, J Mol Biol, 290, 535, 10.1006/jmbi.1999.2854

Engelstädter, 2000, Targeting human T cells by retroviral vectors displaying antibody domains selected from a phage display library, Hum Gene Ther, 11, 293, 10.1089/10430340050016030

Dreier, 2010, Her2-specific multivalent adapters confer designed tropism to adenovirus for gene targeting, J Mol Biol

Bucheit, 2003, An oncolytic measles virus engineered to enter cells through the CD20 antigen, Mol Ther, 7, 62, 10.1016/S1525-0016(02)00033-3

Jäger, 2001, The scFv fragment of the antibody hu4D5-8: evidence for early premature domain interaction in refolding, J Mol Biol, 305, 1111, 10.1006/jmbi.2000.4342

Overbaugh, 2001, Receptors and entry cofactors for retroviruses include single and multiple transmembrane-spanning proteins as well as newly described glycophosphatidylinositol-anchored and secreted proteins, Microbiol Mol Biol Rev, 65, 371, 10.1128/MMBR.65.3.371-389.2001

Buchholz, 1996, Cell entry by measles virus: long hybrid receptors uncouple binding from membrane fusion, J Virol, 70, 3716, 10.1128/JVI.70.6.3716-3723.1996

Moasser, 2007, The oncogene HER2: its signaling and transforming functions and its role in human cancer pathogenesis, Oncogene, 26, 6469, 10.1038/sj.onc.1210477

Baselga, 2009, Novel anticancer targets: revisiting ERBB2 and discovering ERBB3, Nat Rev Cancer, 9, 463, 10.1038/nrc2656

Hasegawa, 2007, Affinity thresholds for membrane fusion triggering by viral glycoproteins, J Virol, 81, 13149, 10.1128/JVI.01415-07

Zhang, 2011, Targeting trastuzumab-resistant breast cancer cells with a lentivirus engineered to bind antibodies that recognize HER-2, Breast Cancer Res Treat, 125, 89, 10.1007/s10549-010-0828-9

Stumpp, 2007, DARPins: a true alternative to antibodies, Curr Opin Drug Discov Devel, 10, 153

Zufferey, 1997, Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo, Nat Biotechnol, 15, 871, 10.1038/nbt0997-871

Demaison, 2002, High-level transduction and gene expression in hematopoietic repopulating cells using a human immunodeficiency [correction of imunodeficiency] virus type 1-based lentiviral vector containing an internal spleen focus forming virus promoter, Hum Gene Ther, 13, 803, 10.1089/10430340252898984

Moll, 2002, Importance of the cytoplasmic tails of the measles virus glycoproteins for fusogenic activity and the generation of recombinant measles viruses, J Virol, 76, 7174, 10.1128/JVI.76.14.7174-7186.2002